Tibofem Tablet

Prescription Required
Store at room temperature (10-30°C)


Tibofem Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).

Tibofem Tablet can be taken with or without food, but better to take it at a fixed time each day for better efficacy. It should be swallowed whole with water. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.

The most common side effects of this medicine are lower abdominal pain, abnormal hair growth, endometrial hyperplasia, vaginal discharge, breast tenderness, genital itching, vaginal bleeding, pelvic pain, cervical thickening,  and weight gain. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs. If you experience any such effects, consult your doctor.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

Benefits of Tibofem Tablet

In Hormone replacement therapy

Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

In Post menopausal osteoporosis

Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. Tibofem Tablet helps maintain bone density and reduces your risk of breaking a bone. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Tibofem Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tibofem

  • Breast pain
  • Vaginal bleeding
  • Weight gain
  • Abnormal hair growth
  • Breast tenderness
  • Cervical thickening
  • Endometrial hyperplasia
  • Genital itching
  • Lower abdominal pain
  • Pelvic pain
  • Vaginal discharge

How to use Tibofem Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tibofem Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Tibofem Tablet works

Tibofem Tablet is a hormonal medication. It has effects similar to estrogen, progesterone and androgen. It substitutes for the loss of estrogen production in postmenopausal women and treats menopausal symptoms such as hot flashes, night sweats and vaginal problems. It also prevents bone loss following menopause.

Safety Advice

It is unsafe to consume alcohol with Tibofem Tablet.
Tibofem Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Information regarding the use of Tibofem Tablet during breastfeeding is not available. Please consult your doctor.
Tibofem Tablet does not usually affect your ability to drive.
There is limited information available on the use of Tibofem Tablet in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Tibofem Tablet in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Tibofem Tablet
34% cheaper
Sibolone Tablet
Serum Institute Of India Ltd
33% cheaper
Maxtib Tablet
Sun Pharmaceutical Industries Ltd
30% cheaper
Livial Tablet
Organon (India) Ltd
88% costlier

Quick Tips

  • Tibofem Tablet is used as a part of hormone replacement therapy to relieve symptoms of menopause such as hot flushes, vaginal dryness, depression, and night sweats.
  • It may also be used for preventing osteoporosis in women who have attained menopause and are at high risk of fractures.
  • Take it at the same time everyday to help you remember to take it.
  • It may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
  • Stop taking Tibofem Tablet and inform your doctor immediately if you get severe headaches, stabbing pains or swelling in one leg, and pain on breathing. These could be symptoms of a blood clot in a vein.
  • Ensure that you regularly check your breasts for any changes and undergo regular breast screening and cervical smear tests while on treatment with this medicine.
  • Do not use Tibofem Tablet if you have a history of blood clots and liver disease. 

Fact Box

Chemical Class
Habit Forming
Therapeutic Class

Interaction with Drugs

Taking Tibofem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Altrom, Cenorol, Cgtrom
Brand(s): Avizole, Womgo, Wormtec
Brand(s): Fetrop, Fertitone, Pifert
Brand(s): Donogen

Patient Concerns

I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue
Dr. Megha Tuli
Obstetrics and Gynaecology
Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.
Having urine burning problem past month. with the homeop medicine 70% relief i got. now i stopped medicine to have. five year back hystectomy done overies still remain. due to computer work eyes get dried and tired. shoulders also pain. past 1.7 year back pain started. some time hot flashes also come suddenly. all blood investigation and u/s are normal. as per dr. advise take sweet less. hair fall are more. no dandruff.
Dr. Megha Tuli
Obstetrics and Gynaecology
It is normal to have hot flashes and these post menopausal symptoms after hysterectomyYou can take hormone therapy if you want however symptoms will recurrent when you stop treatment
Do you have any questions related to Tibofem Tablet ?

User Feedback


Q. Does Tibofem Tablet contain progesterone?

It is a synthetic medicine which is used to fulfill the functions of the normal sex hormones like estrogen and progesterone in the body of women. On taking Tibofem Tablet it is broken down in our body and functions like estrogen, progesterone and a part to testosterone (male sex hormone). It is prescribed to compensate for the loss of estrogen production in postmenopausal women and decrease the menopausal symptoms.

Q. Is Tibofem Tablet a combined HRT?

Yes, Tibofem Tablet is a type of medicine used in hormone replacement therapy (HRT) which is given to post-menopausal women. It is given to prevent the adverse effects on various organs and systems due to decrease in the levels of hormones like estrogen and progesterone. It shows positive effect on different tissues in the body, such as brain, vagina, and bones.

Q. Can Tibofem Tablet be taken during pregnancy?

No, Tibofem Tablet is not to be taken in pregnancy or if you are planning to get pregnant. In case you become pregnant during treatment with this medication you should contact your doctor and the medicine should be withdrawn immediately.

Q. Does Tibofem Tablet help in elevating mood?

Yes, this medicine has shown positive results when given to postmenapausal women as a substitute for the hormonal deprivation. Patients have experienced reduction in the menopausal complaints like persistent fatigue, blunted motivation, and loss of sexual desire. However, consult the doctor regarding any query for your mood problems before you start taking this medication.

Q. Can Tibofem Tablet help in osteoporosis?

Yes, Tibofem Tablet can help in osteoporosis. After menopause some women become prone to develop fragile bones called osteoporosis which can lead to an increased risk of fractures. Tibofem Tablet acts as a replacement for the female sex hormones when given in the post-menopausal phase. These hormones help in increasing bone density. Therefore, taking Tibofem Tablet can prevent bone loss and osteoporosis. Do consult your doctor before starting this medication as you might need other supplemental medications to treat osteoporosis.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Tibolone. London, UK: ADVANZ Pharma; 2016 [revised 26 Apr. 2016]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  2. Tibolone. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2009 [revised 22 Mar. 2016] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of Origin: India

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