Sulpian 100 Tablet CR

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 25 Nov 2025 | 03:05 PM (IST)

Sulpian 100 Tablet CR is a prescription medicine used in the treatment of schizophrenia, a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave.

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General Information

Contains

Amisulpride (100mg)

Marketer

Aviana Formulation Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Sulpian 100 Tablet CR may be taken with or without food, preferably before bedtime. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, vomiting, dryness in the mouth, blurred vision, insomnia, and erectile dysfunction. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain and may increase your blood sugar and cholesterol levels. However, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

Uses of Sulpian Tablet CR

Schizophrenia

Benefits of Sulpian Tablet CR

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Sulpian 100 Tablet CR helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. Take it as prescribed by the doctor and follow your doctor’s instructions carefully.

Side effects of Sulpian Tablet CR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sulpian

Nausea
Vomiting
Dryness in mouth
Constipation
Weight gain
Decreased blood pressure
Dystonia (involuntary muscle contractions)
Akathisia (inability to stay still)
Increased prolactin level in blood
Blurred vision
Insomnia (difficulty in sleeping)
Erectile dysfunction

How to use Sulpian Tablet CR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sulpian 100 Tablet CR may be taken with or without food.

How Sulpian Tablet CR works

Sulpian 100 Tablet CR is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Quick tips

Sulpian 100 Tablet CR helps treat schizophrenia.
Take it at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration as Sulpian 100 Tablet CR can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Do not consume alcohol while on treatment with this medicine as it may worsen the side effects.
It may cause increased weight, blood sugar, cholesterol, and triglycerides (fat) levels. Eat healthy and exercise regularly.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking Sulpian 100 Tablet CR without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Sulpian 100 Tablet CR

Pregnancy

CONSULT YOUR DOCTOR

Sulpian 100 Tablet CR is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Sulpian 100 Tablet CR may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Sulpian 100 Tablet CR may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Sulpian 100 Tablet CR should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Sulpian 100 Tablet CR is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Sulpian with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Amisulpride.

Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Amisulpride.

Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Amisulpride.

Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Amisulpride.

Life-threatening

Voriconazole (Oral Route)

Do not consume Voriconazole with Amisulpride.

Frequently asked questions

Does Sulpian 100 Tablet CR make you sleepy?

Yes, Sulpian 100 Tablet CR may make you sleepy, drowsy, less alert, and may even blur your vision. If you experience these symptoms you should not drive or operate heavy machinery.

When should I take Sulpian 100 Tablet CR?

The time of taking the medicine will be suggested by your doctor depending upon your dose. Doses up to 300 mg can be taken anytime of the day but preferably at the same time each day. Doses more than 300 mg can be taken half in the morning and half in the evening. You can take the medicine during or between meals.

What does Sulpian 100 Tablet CR do to the brain?

Sulpian 100 Tablet CR belongs to antipsychotic class of medicines. It acts against dopamine receptors in the brain. Dopamine is a neurotransmitter which helps in regulating mood and behavior. Schizophrenia is associated with an overactivity of dopamine in the brain, and this overactivity may cause delusions and hallucinations. Sulpian 100 Tablet CR prevents this excessive activity of dopamine in the brain which helps in treating symptoms of schizophrenia.

Does Sulpian 100 Tablet CR help with anxiety?

No, there is no data to support the use of Sulpian 100 Tablet CR in the treatment of anxiety. On the contrary, anxiety is a common side effect of Sulpian 100 Tablet CR.

Can I stop taking Sulpian 100 Tablet CR after some time?

No, you should keep taking Sulpian 100 Tablet CR as long as your doctor has advised. Do not stop the medication even if you feel better. Stopping it suddenly may worsen your condition or symptoms may come back. Talk to your doctor who will gradually reduce your dose.

Who should not take Sulpian 100 Tablet CR?

You should not take Sulpian 100 Tablet CR if you are under 15 years of age, allergic to it, have breast cancer or a tumor known as prolactinoma. Avoid taking Sulpian 100 Tablet CR if you are breastfeeding, have tumor of adrenal glands (pheochromocytoma), or if you are taking certain medicines like levodopa, medicines to treat heart rhythm disorders, etc.

Is Sulpian 100 Tablet CR addictive?

No, there is no evidence to say that Sulpian 100 Tablet CR causes addiction. Also, its use is not known to have any tendency for abuse.

What are the withdrawal symptoms of Sulpian 100 Tablet CR?

Suddenly stopping Sulpian 100 Tablet CR may cause withdrawal symptoms which include nausea, vomiting, sweating, difficulty sleeping, extreme restlessness, muscle stiffness or abnormal movements, or your original condition may come back. Therefore, it is advised to gradually reduce the dose of Sulpian 100 Tablet CR.

Fact Box

Chemical Class

Aminobenzamides

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

Stahl SM, editor. Amisulpride. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 17-22.
Amisulpride. Guildford, Surrey: Zentiva; 2002 [revised 31 Jul. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Amisulpride. South Ruislip, UK: Milpharm Limited; 2018. [Accessed 01 Feb. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amisulpride. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aviana Formulation Pvt Ltd
Address: Plot No 8, 1St Floor Parmanand Industrial Co Op Society Khatodara, Udhana, Surat, Gujarat

Vendor Details

Country of origin: India

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Why we need a prescription?

Sulpian 100 Tablet CR

Save more with additional offers

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Sulpian Tablet CR

Benefits of Sulpian Tablet CR

Side effects of Sulpian Tablet CR

How to use Sulpian Tablet CR

How Sulpian Tablet CR works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Amiodarone (Oral Route)

Aripiprazole (Oral Route)

Ondansetron (Oral Route)

Hydroxyzine (Oral Route)

Voriconazole (Oral Route)

Frequently asked questions

Does Sulpian 100 Tablet CR make you sleepy?

When should I take Sulpian 100 Tablet CR?

What does Sulpian 100 Tablet CR do to the brain?

Does Sulpian 100 Tablet CR help with anxiety?

Can I stop taking Sulpian 100 Tablet CR after some time?

Who should not take Sulpian 100 Tablet CR?

Is Sulpian 100 Tablet CR addictive?

What are the withdrawal symptoms of Sulpian 100 Tablet CR?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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