Simponi 50mg Injection

Golimumab (50mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Simponi 50mg Injection is a medicine used in the treatment of rheumatoid arthritis. It provides relief from swelling, pain, and redness associated with the condition and improves physical function.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Mar 2026 | 11:29 AM (IST)

₹23918 MRP ₹2657810% off

Gurgaon

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General Information

Contains

Golimumab (50mg)

Marketer

Johnson & Johnson Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Simponi 50mg Injection is genrally administered by a doctor or a nurse and should not be self-administered. Get the injection regularly for as long as the doctor has prescribed to get the maximum benefit from it. Continue taking it as recommended by your doctor and complete the dose even if you feel better.

Some of the common side effects of this medicine include upper respiratory tract infection and inflammation of the throat and nasal passages (nasopharyngitis). Talk to your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking it, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also tell your doctor about all the other medicines you are taking. It is important for pregnant and breastfeeding women to ask the advice of their doctors before taking this medicine.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Simponi Injection

Treatment of Rheumatoid arthritis

Benefits of Simponi Injection

Treatment of Rheumatoid arthritis
Simponi 50mg Injection reduces pain, stiffness, and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. The medicine is given as an injection is given by a doctor or nurse and should not be self-administered.

Side effects of Simponi Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Simponi

Upper respiratory tract infection
Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Simponi Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Simponi Injection works

Simponi 50mg Injection blocks the action of certain chemical messengers that are responsible for inflammation, swelling and redness associated with certain joint diseases.

Quick tips

Always use Simponi 50mg Injection under medical supervision, preferably into the thigh or abdomen.
Consider rotating the injection site each time to prevent skin problems.
Monitor for signs of infection (fever, cough, skin redness) since this medicine weakens immune defenses. Report anything unusual to your doctor.
Avoid live vaccines during treatment as the immune suppression due to Simponi 50mg Injection can make such vaccines risky.
Inform your doctor before starting Simponi 50mg Injection if you have TB or hepatitis, or have lived in regions where such infections are common.
Do not skip doses or stop suddenly, as this may reduce effectiveness. Maintain a consistent schedule as advised by your doctor.

Safety advice

Alcohol

There is no data available. Please consult doctor before consuming the drug.

Pregnancy

CONSULT YOUR DOCTOR

Simponi 50mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Simponi 50mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Simponi 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

There is no data available. Please consult doctor before consuming the drug.

Liver

There is no data available. Please consult doctor before consuming the drug.

Interaction with drugs

Taking Simponi with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Golimumab.

Life-threatening

Tocilizumab (Injection Route)

Do not consume Tocilizumab with Golimumab.

Life-threatening

Vedolizumab (Injection Route)

Do not consume Vedolizumab with Golimumab.

Severe

Adalimumab (Injection Route)

Do not consume Adalimumab with Golimumab.

Severe

Abatacept (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment closely.

Frequently asked questions

What is Simponi 50mg Injection used for?

Simponi 50mg Injection is used to treat autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps by reducing inflammation and slowing disease progression.

Who should not take Simponi 50mg Injection?

Individuals should not use Simponi 50mg Injection if they have a serious infection like tuberculosis or sepsis, have a history of certain cancers, heart failure, or demyelinating diseases (like multiple sclerosis), or are allergic to golimumab or any of the ingredients in Simponi 50mg Injection.

Can Simponi 50mg Injection cause severe side effects?

Yes, Simponi 50mg Injection may cause serious side effects such as severe infections like tuberculosis or fungal infections, liver problems or hepatitis B reactivation, worsening heart failure, nervous system disorders, and lymphoma or skin cancer (in rare cases).

What should I tell my doctor before starting Simponi 50mg Injection?

Before starting Simponi 50mg Injection, you should inform your doctor if you have had tuberculosis or other chronic infections, have hepatitis B or liver disease, have had cancer, heart problems, or numbness/tingling, or if you plan to receive any vaccines.

What are the signs I should stop Simponi 50mg Injection and call a doctor immediately?

During Simponi 50mg Injection use, you should stop using Simponi 50mg Injection and seek emergency help if you notice high fever, persistent cough, weight loss, yellowing of skin or eyes (liver issues), shortness of breath or swelling (heart issues), vision problems, muscle weakness, confusion, swollen lymph nodes, or unexplained bleeding or bruising.

Is Simponi 50mg Injection a long-term treatment for autoimmune diseases?

Yes, Simponi 50mg Injection is often used as a long-term therapy to control chronic autoimmune inflammation. Regular monitoring and blood tests are needed to check for infections, liver function, and immune response.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Golimumab [Prescribing Information]. Horsham, PA: Janssen Biotech, Inc.; 2025. [Accessed 02 Jan. 2026]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Johnson & Johnson Ltd
Address: 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060 / LBS Marg Mulund (West), Mumbai 400080

Vendor Details

Country of origin: Switzerland

Lab tests offered by us

Why we need a prescription?

Simponi 50mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Simponi Injection

Benefits of Simponi Injection

Side effects of Simponi Injection

How to use Simponi Injection

How Simponi Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Natalizumab (Injection Route)

Tocilizumab (Injection Route)

Vedolizumab (Injection Route)

Adalimumab (Injection Route)

Abatacept (Injection Route)

Frequently asked questions

What is Simponi 50mg Injection used for?

Who should not take Simponi 50mg Injection?

Can Simponi 50mg Injection cause severe side effects?

What should I tell my doctor before starting Simponi 50mg Injection?

What are the signs I should stop Simponi 50mg Injection and call a doctor immediately?

Is Simponi 50mg Injection a long-term treatment for autoimmune diseases?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests