Simenda 12.5mg Injection

Levosimendan (12.5mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Simenda 12.5mg Injection is a medicine used for the treatment of heart failure. It increases the pumping activity of the heart and relaxes the blood vessels, which further improves the blood circulation throughout the body.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 08 May 2026 | 05:15 PM (IST)

₹526 MRP ₹584.3410% off

Gurgaon

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General Information

Contains

Levosimendan (12.5mg)

Marketer

Lupin Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Simenda 12.5mg Injection is administered under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide the dose and duration of the medicine for you. The doctor will closely monitor your blood pressure, heart rate, and ECG until you become stable. You can also improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress.

The most common side effects of this medicine include hypotension (low blood pressure), increased heart rate, nausea, constipation, and headache. This medicine may be used with caution for some people. Thus, you must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of Simenda Injection

Heart Failure

Benefits of Simenda Injection

Heart Failure
Simenda 12.5mg Injection is used in heart failure to help improve the heart's ability to pump blood more effectively. It can reduce symptoms like shortness of breath, fatigue, and fluid buildup by supporting heart function during periods of acute worsening. This may help patients feel more stable and improve overall circulation, especially during hospitalization or critical care.

Side effects of Simenda Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Simenda

Headache
Increased heart rate
Nausea
Constipation
Hypotension (low blood pressure)

How to use Simenda Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Simenda Injection works

Simenda 12.5mg Injection makes the heart pump blood with more strength and force, which increases the blood circulation throughout the body.

Quick tips

Simenda 12.5mg Injection is given as a drip into a vein (intravenous infusion) under the supervision of a doctor.
It makes you feel dizzy or lightheaded. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
You will be constantly monitored for changes in ECG, blood pressure and heart rate for at least 3 days after the treatment or until you become stable.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Simenda 12.5mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Simenda 12.5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Simenda 12.5mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

NOT RELEVANT

Not relevant, as Simenda 12.5mg Injection is intended for use in hospitalized patients.

Kidney

CAUTION

Simenda 12.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Simenda 12.5mg Injection is not recommended in patients with severe kidney disease.

Liver

UNSAFE

Simenda 12.5mg Injection is unsafe to use in patients with liver disease and should be avoided.
No dose adjustment is recommended in patients with mild to moderate liver disease.

Interaction with drugs

Taking Simenda with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Mild