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Isosorbide Mononitrate



Isosorbide Mononitrate is used in the treatment of angina and heart failure.

How it works

Isosorbide mononitrate lowers the workload of the heart. As a result, the heart muscles do not need much blood and oxygen supply.

Common side effects

Headache, Dizziness, Increased heart rate, Flushing of face, Orthostatic hypotension (sudden lowering of blood pressure on standing)

Available Medicine

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    Abbott India Ltd
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Expert advice

Take isosorbide mononitrate by mouth on an empty stomach with a full glass of water. Do not take isosorbide mononitrate, If you are allergic to isosorbide mononitrate or any of the other ingredients. Check with your doctor before taking isosorbide mononitrate, if you are pregnant, planning to become pregnant, or are breast-feeding.
  • Do not drink alcohol. 
  • Do not drive or operate machinery as the drug can make you dizzy or drowzy.
Isosorbide mononitrate is not indicated for relief of acute anginal attacks The drug can  can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking isosorbide mononitrate. Ask your doctor before using any headache pain medication.

Frequently asked questions

Isosorbide Mononitrate


Is isosorbide mononitrate a beta blocker/ a blood thinner/ a calcium channel blocker/a statin /ace inhibitor/ a diuretic/ a narcotic?
No, isosorbide mononitrate is vasodilator. It is not a beta blocker, a blood thinner, a calcium channel blocker, ace inhibitor/ a diuretic or a statin. It is not a narcotic but narcotic symptoms may develop in some people


Does isosorbide mononitrate cause erectile dysfunction (ed)/ lower blood pressure/hair loss?
Isosorbide mononitrate does not cause erectile dysfunction but should not be used with the drugs such as Viagra used to treat ED. Low blood pressure is a common side effect of isosorbide mononitrate. Hair loss is not common, but may occur in some especially in older (60+) females


Can isosorbide mononitrate be crushed/ cut half/ be split?
Do not crush, split, cut half or chew the isosorbide mononitrate tablets. Its efficacy may get reduce. Always follow your doctor’s advice regarding its use

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Is isosorbide mononitrate the same as isosorbide dinitrate?
Isosorbide mononitrate is the active metabolite of isosorbide dinitrate and is primarily used in the management of chronic stable angina. It has high bioavailability and a longer half-life (4-6 hours) than isosorbide dinitrate


Can i take paracetamol with isosorbide mononitrate?
No interactions are found for paracetamol with isosorbide mononitrate, but it does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist


Can isosorbide mononitrate get you high?
No, isosorbide mononitrate does not get you high


Can isosorbide mononitrate be taken at night?
It is better to take isosorbide mononitrate in the morning during the time patients are active and leave them drug free during sleep.

Content on this page was last updated on 11 April, 2017, by Dr. Varun Gupta (MD Pharmacology)