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    Isosorbide Mononitrate

    Information about Isosorbide Mononitrate

    Isosorbide mononitrate uses

    Isosorbide Mononitrate is used in the treatment of chest pain (Angina).

    How isosorbide mononitrate works

    Isosorbide mononitrate is in a group of drugs called nitrates. It reduces the workload of the heart. As a result, the heart muscle does not need as much blood and oxygen supply.

    Common side effects of isosorbide mononitrate

    Headache, Dizziness, Increased heart rate, Flushing of face, Orthostatic hypotension (sudden lowering of blood pressure on standing)

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    Expert advice for Isosorbide Mononitrate

    • Headache (‘nitrate headache’) may occur but should go away after a few days of continued treatment.
    • You may develop tolerance to Isosorbide Mononitrate with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
    • Eat healthy (low-fat, high-fibre, low-sodium diet), quit smoking, limit alcohol intake, increase your physical activity, watch your weight, and reduce stress.
    • Notify your doctor about other medicines (eg. sildenafil, tadalafil or vardenafil) that you are taking as Isosorbide Mononitrate may interact with them and cause a serious fall in blood pressure. This may lead to collapse, unconsciousness and could be fatal.

    Frequently asked questions for Isosorbide Mononitrate

    Isosorbide Mononitrate

    Q. Does Isosorbide Mononitrate cause erectile dysfunction (ed)/ lower blood pressure/hair loss?
    Isosorbide Mononitrate does not cause erectile dysfunction but should not be used with the drugs such as Viagra used to treat ED. Low blood pressure is a common side effect of Isosorbide Mononitrate. Hair loss is not common, but may occur in some especially in older (60+) females
    Q. Is isosorbide mononitrate the same as isosorbide dinitrate?
    Isosorbide mononitrate is the active metabolite of isosorbide dinitrate and is primarily used in the management of chronic stable angina. It has high bioavailability and a longer half-life (4-6 hours) than isosorbide dinitrate
    Q. Can Isosorbide Mononitrate get you high?
    No, Isosorbide Mononitrate does not get you high
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    Q. Is isosorbide mononitrate a beta blocker/ a blood thinner/ a calcium channel blocker/a statin /ace inhibitor/ a diuretic/ a narcotic?
    No, isosorbide mononitrate is vasodilator. It is not a beta blocker, a blood thinner, a calcium channel blocker, ace inhibitor/ a diuretic or a statin. It is not a narcotic but narcotic symptoms may develop in some people
    Q. Can Isosorbide Mononitrate be crushed/ cut half/ be split?
    Do not crush, split, cut half or chew the Isosorbide Mononitrate tablets. Its efficacy may get reduce. Always follow your doctor’s advice regarding its use
    Q. Can i take paracetamol with isosorbide mononitrate?
    No interactions are found for paracetamol with isosorbide mononitrate, but it does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist
    Q. Can Isosorbide Mononitrate be taken at night?
    It is better to take Isosorbide Mononitrate in the morning during the time patients are active and leave them drug free during sleep.

    Content on this page was last updated on 23 November, 2017, by Dr. Varun Gupta (MD Pharmacology)