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    Isosorbide Dinitrate

    Information about Isosorbide Dinitrate

    Isosorbide dinitrate uses

    Isosorbide Dinitrate is used in the treatment of chest pain (Angina) and heart failure.

    How isosorbide dinitrate works

    Isosorbide dinitrate is in a group of drugs called nitrates. It reduces the workload of the heart. As a result, the heart muscle does not need as much blood and oxygen supply.

    Common side effects of isosorbide dinitrate

    Headache, Flushing of face, Dizziness, Increased heart rate, Orthostatic hypotension (sudden lowering of blood pressure on standing)

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    Expert advice for Isosorbide Dinitrate

    • Headache (‘nitrate headache’) may occur but should go away after a few days of continued treatment.
    • You may develop tolerance to Isosorbide Dinitrate with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
    • Eat healthy (low-fat, high-fibre, low-sodium diet), quit smoking, limit alcohol intake, increase your physical activity, watch your weight, and reduce stress.
    • Notify your doctor about other medicines (eg. sildenafil, tadalafil or vardenafil) that you are taking as Isosorbide Dinitrate may interact with them and cause a serious fall in blood pressure. This may lead to collapse, unconsciousness and could be fatal.

    Frequently asked questions for Isosorbide Dinitrate

    Isosorbide Dinitrate

    Q. What is Isosorbide Dinitrate and what is it used for?
    Isosorbide Dinitrate is used to prevent and treat angina pectoris and as an adjunctive treatment in severe acute or chronic congestive cardiac failure.
    Q. How does Isosorbide Dinitrate work?
    Isosorbide Dinitrate belongs to a group of medicines called organic nitrates and it works by widening the blood vessels in your heart to allow an increased amount of blood flow to areas which need it.
    Q. Does Isosorbide Dinitrate lower heart rate?
    No, Isosorbide Dinitrate is not known to lower heart rate.

    Content on this page was last updated on 23 November, 2017, by Dr. Varun Gupta (MD Pharmacology)