Isosorbide Dinitrate

Information about Isosorbide Dinitrate

Isosorbide Dinitrate Uses

Isosorbide Dinitrate is used in the treatment of Angina (heart-related chest pain) and Heart failure.

How Isosorbide Dinitrate works

Isosorbide Dinitrate is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain).

Common side effects of Isosorbide Dinitrate

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MD (Pharmacology), MBBS
Last updated
10 Jun 2022 | 04:09 PM (UTC)

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Available Medicine for Isosorbide Dinitrate

IsordilIpca Laboratories Ltd
92 variant(s)
NonitAventure Pharma
501 variant(s)
MonotagIkon Remedies Pvt Ltd
82 variant(s)
CardicapSun Pharmaceutical Industries Ltd
60 to ₹992 variant(s)
AnzidinStadmed Pvt Ltd
5 to ₹62 variant(s)
IsocrateRoussel Laboratories Pvt Ltd
311 variant(s)
IsmotagInnovative Pharmaceuticals
82 variant(s)
SorbaDaxia Healthcare
491 variant(s)

Expert advice for Isosorbide Dinitrate

  • Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
  • Isosorbide Dinitrate may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Do not consume alcohol while taking Isosorbide Dinitrate as it may cause increased dizziness.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • You may develop tolerance to Isosorbide Dinitrate with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Isosorbide Dinitrate as it may cause low blood pressure.

Frequently asked questions for Isosorbide Dinitrate

Isosorbide Dinitrate

Q. What is Isosorbide Dinitrate and what is it used for?

Isosorbide Dinitrate belongs to a group of medicines called organic nitrates. Isosorbide Dinitrate is used to prevent and treat angina pectoris and as an adjunctive treatment in severe acute or chronic congestive cardiac failure.

Q. How does Isosorbide Dinitrate work?

Isosorbide Dinitrate works by widening the blood vessels in your heart to allow an increased amount of blood flow to areas which need it.

Q. Does Isosorbide Dinitrate lower heart rate?

No, Isosorbide Dinitrate does not lower heart rate. However, in some cases, one may experience reflex tachycardia (fast heart rate) while using nitrates such as Isosorbide Dinitrate.

Q. Does Isosorbide Dinitrate lower blood pressure?

Yes, Isosorbide Dinitrate lowers blood pressure. This medicine widens the blood vessels and decreases the resistance in them, causing a fall in blood pressure. This fall in blood pressure may in turn decrease the heartbeat which can lead to angina. This medicine should be avoided in people who already have low blood pressure. Discuss with your doctor if you have any concerns.

Q. Can I take sildenafil while taking Isosorbide Dinitrate?

No, you should not take sildenafil along with Isosorbide Dinitrate. Both these medicines lower blood pressure and belong to the same class. Taking these two medicines together may cause significant decrease in blood pressure which can cause fainting or even a heart attack. Along with this, avoid taking other medicines which belong to the same class such as vardenafil and tadalafil.


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