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Serestin Injection

Haloperidol (5mg/ml)
Genuine
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Serestin Injection is used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It may also be used to treat Tourette syndrome (chronic multiple motor and vocal problems and involuntary responses) in adults and children.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
₹6.3 MRP ₹6.87% off 
 
 
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General Information

The content is shown in English
Serestin Injection image
Serestin Injection image
Serestin Injection image

Product introduction

Serestin Injection can also be used for treating psychosis, mania, severe behavior problems in adults and children. It is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Serestin Injection

Benefits of Serestin Injection

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings, and behavior become abnormal. Serestin Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the maximum benefits.

Side effects of Serestin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Serestin
  • Abnormality of voluntary movements
  • Constipation
  • Dryness in mouth
  • Increased prolactin level in blood
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Weight gain

How to use Serestin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Serestin Injection works

Serestin Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

  • Serestin Injection helps treat schizophrenia.
  • It is less likely to cause weight gain as compared to other similar medicines.
  • Use caution while driving or doing anything that requires concentration as Serestin Injection may cause dizziness and sleepiness.
  • Avoid drinking alcohol while taking this medicine as it can cause increased dizziness.
  • Inform your doctor if you experience any abnormal movements or have difficulty controlling movements.
  • It may affect how your body regulates your temperature. Avoid getting dehydrated and drink plenty of fluids.
  • Your doctor may check your heart function and level of electrolytes such as sodium and magnesium before you start treatment with this medicine and regularly thereafter.
  • Do not stop taking Serestin Injection without talking  to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Serestin Injection may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Serestin Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Serestin Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
If Serestin Injection is used, monitor the baby for excessive sleepiness.
Driving

Driving

UNSAFE
Serestin Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Serestin Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
However, patients with severe kidney disease may need to be started at a lower dose as it may cause excessive sleepiness in these patients.
Liver

Liver

CAUTION
Serestin Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Serestin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Amiodarone (Oral Route)

Do not consume Amiodarone with Haloperidol.
Life-threatening

Aripiprazole (Oral Route)

Do not consume Aripiprazole with Haloperidol.
Life-threatening

Clozapine (Oral Route)

Do not consume Clozapine with Haloperidol. If concurrent use is essential, watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite or nausea and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Haloperidol.
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Haloperidol.

Fact Box

Chemical Class

Alkyl- phenylketones

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

  1. Stahl SM, editor. Haloperidol. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 291-96.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 646-48.
  3. Haloperidol. Titusville, NJ: Janssen Pharmaceuticals; 2005 [revised Jan. 2016]. [Accessed 25 Mar. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004;80(5):4-6. [Accessed 20 Mar. 2019] (online) Available from:
  5. Haloperidol [EMC SmPC]. London, UK: ADVANZ Pharma; 1989 [revised 1 Sep. 2017]. [Accessed 25 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biogen Serums Pvt Ltd
Address: R6 Sector, A 104, Life Republic Marunji, Hinjewadi - 411057

Vendor Details

Country of origin: India
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