Samexa 25mg Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 05 Jan 2026 | 05:03 PM (IST)

Samexa 25mg Tablet is an aromatase inhibitor. It is used in the treatment of breast cancer in women who have gone through menopause. It works by adjusting the level of estrogen and helps in slowing down the growth of cancer cells.

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₹562 MRP ₹653.5914% off

Samexa 25mg Tablet is currently sold out

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Aromasin 25mg Tablet

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Samexa 25mg Tablet

strip of 10 tablets

₹562

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Same composition

Aromasin 25mg Tablet

strip of 15 tablets

Exemestane (25mg)

by Pfizer Ltd

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₹4625

₹308.33 per tablet

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General Information

Contains

Exemestane (25mg)

Marketer

Samarth Life Sciences Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Samexa 25mg Tablet is also used in combination with medication in early cancer to prevent the risk of coming back. It should be taken with food, but take it at the same time every day to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you.

The most common side effects of the medicine include insomnia (difficulty sleeping), headache, nausea, increased appetite, and joint pain If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you are not gone through menopause and still having menstrual periods, or you have a problem with the liver or kidney. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density.

Uses of Samexa Tablet

Breast cancer

Benefits of Samexa Tablet

Breast cancer
Breast cancer is a disease where cells in the breast grow uncontrollably, often influenced by hormones like estrogen. Samexa 25mg Tablet is used in hormone receptor-positive breast cancer, particularly in postmenopausal women. It lowers estrogen levels in the body, and it helps slow or stop the growth of hormone-sensitive tumors. This improves treatment outcomes, reduces the chance of recurrence, and supports long-term disease control.

Side effects of Samexa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samexa

Headache
Dizziness
Rash
Nausea
Increased sweating
Fracture
Vomiting
Weakness
Abdominal pain
Osteoporosis
Diarrhea
Peripheral edema
Insomnia (difficulty in sleeping)
Decreased white blood cell count (lymphocytes)
Low blood platelets
Decreased appetite
Depression
Carpal tunnel syndrome
Paresthesia (tingling or pricking sensation)
Hot flushes
Constipation
Urticaria
Hair loss
Itching
Increased appetite

How to use Samexa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Samexa 25mg Tablet should be taken with or after food.

How Samexa Tablet works

Samexa 25mg Tablet is an aromatase inhibitor. It works by lowering the amount of estrogen (a natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

All substitutes for Samexa 25mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Samexa 25mg Tablet is used for the treatment of hormone dependent breast cancer in postmenopausal women.
Take it at the same time everyday, preferably after food.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements, if needed.
Do not take Samexa 25mg Tablet if you are pregnant or breastfeeding.
Samexa 25mg Tablet is used for the treatment of hormone dependent breast cancer in postmenopausal women.
Take it at the same time everyday, preferably after food.
It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Your doctor may regularly check your Vitamin D level and bone mineral density and suggest supplements, if needed.
Do not take Samexa 25mg Tablet if you are pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Samexa 25mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Samexa 25mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Samexa 25mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Samexa 25mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

UNSAFE

Samexa 25mg Tablet is unsafe to use in patients with kidney disease and should be avoided.

Liver

UNSAFE

Samexa 25mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Samexa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Carbamazepine (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Carbamazepine may reduce blood levels of Exemestane.

Moderate

Enzalutamide (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Enzalutamide may reduce blood levels of Exemestane.

Moderate

Fosphenytoin (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Fosphenytoin may reduce blood levels of Exemestane.

Moderate

Phenobarbitone (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Phenobarbitone may reduce blood levels of Exemestane.

Moderate

Phenobarbitone (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Phenobarbitone may reduce blood levels of Exemestane.

Frequently asked questions

What is Samexa 25mg Tablet and what is it used for?

Samexa 25mg Tablet contains a medicine Exemestane, which is used to treat breast cancer in women who have gone through menopause.

How and in what dose should I use Samexa 25mg Tablet?

Take it as per the advice of your doctor. The number of doses you take each day, and the duration depends on your medical problem. Take your tablet at about the same time every day to ensure consistent levels of medicine in your body. You can take it with or without food. Treatment with Samexa 25mg Tablet may be long term and you may require to take it for several years.

What if I forget to take Samexa 25mg Tablet?

If you forget to take a dose of Samexa 25mg Tablet, take it as soon as you remember. If it is almost time to your next dose, skip it and follow your usual dosing schedule. Do not take two doses at the same time to make up for the forgotten one.

What are the common side effects of using Samexa 25mg Tablet?

Most common side effects of using Samexa 25mg Tablet are hot flashes, feeling tired, joint pain , headache, trouble sleeping, increased sweating, depression, feeling anxious, upset stomach and difficulty in breathing. If any of these side effects bother you, consult your doctor.

Can I stop taking Samexa 25mg Tablet?

Do not stop taking Samexa 25mg Tablet without talking to your doctor, even if you start to feel well.

What is Samexa 25mg Tablet and what is it used for?

Samexa 25mg Tablet is a non-steroidal medicine, which is used to treat breast cancer in women who have gone through menopause.

How and in what dose should I use Samexa 25mg Tablet?

What if I forget to take Samexa 25mg Tablet?

Can I stop taking Samexa 25mg Tablet?

Do not stop taking Samexa 25mg Tablet without talking to your doctor, even if you start to feel well.

What are the common side effects of using Samexa 25mg Tablet?

Fact Box

Chemical Class

Androgen derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Aromatase Inhibitors

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1762-63.
Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 527-28.
Exemestane. New York, New York: Pfizer; 1999 [revised May 2014]. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Exemestane [Prescribing Information]. New York, NY: Pharmacia & Upjohn Co; 2018. [Accessed 20 Feb. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090. || 136, New Ashirwad Ind. Est. No.5, Ram Mandir Road, Goregaon (W), Mumbai - 400 104, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Samexa 25mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Samexa Tablet

Benefits of Samexa Tablet

Side effects of Samexa Tablet

How to use Samexa Tablet

How Samexa Tablet works

All substitutes for Samexa 25mg Tablet

Xtane Tablet

Aromasin 25mg Tablet

Exesin 25 Tablet

Aromasin 25mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Carbamazepine (Oral Route)

Enzalutamide (Oral Route)

Fosphenytoin (Injection Route)

Phenobarbitone (Oral Route)

Phenobarbitone (Injection Route)

Frequently asked questions

What is Samexa 25mg Tablet and what is it used for?

How and in what dose should I use Samexa 25mg Tablet?

What if I forget to take Samexa 25mg Tablet?

What are the common side effects of using Samexa 25mg Tablet?

Can I stop taking Samexa 25mg Tablet?

What is Samexa 25mg Tablet and what is it used for?

How and in what dose should I use Samexa 25mg Tablet?

What if I forget to take Samexa 25mg Tablet?

Can I stop taking Samexa 25mg Tablet?

What are the common side effects of using Samexa 25mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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