Samdox Plus Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 02 Feb 2026 | 07:41 PM (IST)

Samdox Plus Injection is an antibiotic medicine used to treat bacterial infections in your body. It is effective in some infections of the lungs, urinary tract, eyes, and others. It kills bacteria, which helps to improve your symptoms and cure the infection.

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Doxicip Injection

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Samdox Plus Injection

vial of 1 Injection

₹482

~~₹527.73~~

Same composition

Doxicip Injection

vial of 1 Injection

Doxycycline (100mg)

by Cipla Ltd

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General Information

Contains

Doxycycline (100mg)

Marketer

Biosam Life Science Private Limited

Storage

Store below 25°C

The content is shown in English

Product introduction

Samdox Plus Injection is also used to treat many sexually transmitted diseases. It helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) into a vein by a doctor or a nurse. You should get the injection regularly at evenly spaced intervals for maximum benefits. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

The most common side effects of this medicine include skin reaction on exposure to sunlight (photosensitivity), vomiting, nausea, and diarrhea. Avoid excessive sun exposure and use sunscreen and protective clothing when outdoors. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics. You should also let your doctor know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. It may blur your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Uses of Samdox Plus Injection

Benefits of Samdox Plus Injection

Treatment of Bacterial infections
Samdox Plus Injection is a versatile antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach and intestines. It can also be used to treat sexually transmitted diseases. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Treatment of Acne
Samdox Plus Injection treats acne, commonly called pimples. It kills the acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. The earlier you start taking it, the less likely you are to get scars. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Samdox Plus Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Samdox Plus

Vomiting
Nausea
Photosensitivity
Rash
Anaphylactic reaction
Headache
Fast heart rate
Hypotension (low blood pressure)

How to use Samdox Plus Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Samdox Plus Injection works

Samdox Plus Injection is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

All substitutes for Samdox Plus Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Your doctor has prescribed Samdox Plus Injection to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Avoid excessive sun exposure and use sunscreen and protective clothing when outdoors.
Your doctor has prescribed Samdox Plus Injection to cure your infection and improve symptoms.
It should be taken on an empty stomach.
Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Samdox Plus Injection affects you.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
It can lower the efficacy of birth control pills. Use an alternative method of contraception ( condom, diaphragm, spermicide) while taking this medication.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not take antacids or medicines containing zinc or iron at least 2 hours before or 6 hours after taking Samdox Plus Injection.
Discontinue Samdox Plus Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Samdox Plus Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Samdox Plus Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Samdox Plus Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Samdox Plus Injection may cause temporary visual disturbances. Do not drive until your vision is clear.
Visual disturbances such as blurring of vision may occur during treatment with doxycycline.

Kidney

CAUTION

Samdox Plus Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease.

Liver

CAUTION

Samdox Plus Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Samdox Plus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Tretinoin (Oral Route)

Do not consume Tretinoin with Doxycycline.

Severe

Isotretinoin (Oral Route)

Do not consume Isotretinoin with Doxycycline.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Doxycycline. Please consult your doctor. Doxycycline may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Acitretin (Oral Route)

Do not consume Acitretin with Doxycycline.

Severe

Phenindione (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor your treatment and adjust the doses as per the observations. Doxycycline may increase the effect of Phenindione.

Frequently asked questions

How long does Samdox Plus Injection takes to work?

Usually, Samdox Plus Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Can the use of Samdox Plus Injection cause diarrhea?

Yes, the use of Samdox Plus Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.

Fact Box

Chemical Class

Tetracyclines

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Bacterial Protein Synthesis Inhibitors- Tetracyclines

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Rosenthal PJ. Clinical Pharmacology of the Antihelmenthic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 926.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 433.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biosam Life Science Private Limited
Address: G-9, 222, KARADVA ROAD, DINDOLI, SURAT, GUJARAT, PIN- 394210, INDIA, MOB- 9470216982, 9504896445

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Samdox Plus Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Samdox Plus Injection

Benefits of Samdox Plus Injection

Side effects of Samdox Plus Injection

How to use Samdox Plus Injection

How Samdox Plus Injection works

All substitutes for Samdox Plus Injection

Doxicip Injection

Cudox Injection

Doxyguard 100mg Injection

Doxodac 100mg Injection

Desidox 100mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tretinoin (Oral Route)

Isotretinoin (Oral Route)

Cholera Vaccine (Inactivated) (Oral Route)

Acitretin (Oral Route)

Phenindione (Oral Route)

Frequently asked questions

How long does Samdox Plus Injection takes to work?

Can the use of Samdox Plus Injection cause diarrhea?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests