Rositaz 4mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 31 Mar 2026 | 02:28 PM (IST)

Rositaz 4mg Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

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General Information

Contains

Rosiglitazone (4mg)

Marketer

RPG Life Sciences Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Rositaz 4mg Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include blurred vision, numbness, and bone fracture. Please consult your doctor if these bother you or persist for a longer duration.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Rositaz Tablet

Type 2 diabetes mellitus

Benefits of Rositaz Tablet

Type 2 diabetes mellitus
Type 2 diabetes mellitus is a chronic condition where the body either does not produce enough insulin or cannot use it effectively, leading to high blood sugar levels. Rositaz 4mg Tablet is used in the management of type 2 diabetes to help improve blood sugar control. When taken along with proper diet and exercise, it supports better long-term glucose management, helping reduce the risk of complications like nerve damage, kidney problems, and eye issues associated with uncontrolled diabetes.

Side effects of Rositaz Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rositaz

Blurred vision
Numbness
Bone fracture
Respiratory tract infection

How to use Rositaz Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rositaz 4mg Tablet may be taken with or without food.

How Rositaz Tablet works

Rositaz 4mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Quick tips

Rositaz 4mg Tablet has been withdrawn from the market due to an increased risk of heart attack and heart-related deaths.
Rositaz 4mg Tablet helps to control blood sugar level and avoid long-term complications.
Full effects may be visible after several weeks of starting Rositaz 4mg Tablet. Keep taking it as prescribed by your doctor.
Weight gain, headache, and swelling due to fluid build-up may occur.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
May not be suitable for patients with a history of heart failure or bladder cancer.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Rositaz 4mg Tablet.
Take it only as per dose and duration suggested by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Rositaz 4mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Rositaz 4mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Rositaz 4mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Rositaz 4mg Tablet may cause side effects that could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Rositaz 4mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Rositaz 4mg Tablet in patients with liver disease.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.

Interaction with drugs

Taking Rositaz with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Severe

Human insulin (Injection Route)

Do not consume Rosiglitazone with Human insulin.

Moderate

Clopidogrel (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may adjust the doses as per the observations. Clopidogrel may raise blood levels of Rosiglitazone.

Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Moderate

Saxagliptin (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Rosiglitazone may raise blood levels of the active form of Saxagliptin.

Frequently asked questions

Can Rositaz 4mg Tablet be used along with glimepiride in diabetes?

Rositaz 4mg Tablet when added to Glimepiride in patients with diabetes mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood glucose control related to a reduction in the insulin resistance.

How to use Rositaz 4mg Tablet?

Rositaz 4mg Tablet is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.

How does Rositaz 4mg Tablet cause oedema?

Rositaz 4mg Tablet increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.

How does Rositaz 4mg Tablet cause heart failure?

Rositaz 4mg Tablet can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).

Can Rositaz 4mg Tablet be used in depression?

Rositaz 4mg Tablet, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study

Fact Box

Chemical Class

Phenol ethers

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Thiazolidinediones (TZD) and PPAR Gamma Agonists

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 743.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1236-37.
Rosiglitazone. Philadelphia, Pennsylvania: SmithKline Beecham Pharmaceuticals; 1999. [Accessed 22 Feb. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: RPG Life Sciences Ltd
Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA

Vendor Details

Country of origin: India

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Rositaz 4mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Rositaz Tablet

Benefits of Rositaz Tablet

Side effects of Rositaz Tablet

How to use Rositaz Tablet

How Rositaz Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Human insulin (Injection Route)

Clopidogrel (Oral Route)

Asparaginase (Injection Route)

Saxagliptin (Oral Route)

Frequently asked questions

Can Rositaz 4mg Tablet be used along with glimepiride in diabetes?

How to use Rositaz 4mg Tablet?

How does Rositaz 4mg Tablet cause oedema?

How does Rositaz 4mg Tablet cause heart failure?

Can Rositaz 4mg Tablet be used in depression?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests