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Type 2 diabetes mellitus.

How it works

Rosiglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, rosiglitazone enhances tissue sensitivity to insulin.

Common side effects

Vomiting, Nausea, Back pain, Cardiac disorder, Cold symptoms, Nasal congestion, Fluid retention, Limb swelling, Headache, Loss of appetite, Running nose, Sore throat, Stomach pain


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)