Information about Rosiglitazone

Rosiglitazone Uses

Type 2 diabetes mellitus.

How Rosiglitazone works

Rosiglitazone is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Common side effects of Rosiglitazone

Headache, Back pain, Edema (swelling), Sinus inflammation, Upper respiratory tract infection, Liver injury, Increased glucose level in blood, Fatigue, Diarrhea, Anemia (low number of red blood cells)
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Reviewed By
MD Pharmacology, MBBS
Last updated
13 Jun 2023 | 11:26 AM (UTC)

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Available Medicine for Rosiglitazone

RoglinAristo Pharmaceuticals Pvt Ltd
56 to ₹782 variant(s)
AvandiaGlaxo SmithKline Pharmaceuticals Ltd
110001 variant(s)
RezultSun Pharmaceutical Industries Ltd
1001 variant(s)
RositusAretaeus Pharmaceuticals
21 to ₹543 variant(s)
SenziaCipla Ltd
60 to ₹1002 variant(s)
WindiaGlaxo SmithKline Pharmaceuticals Ltd
57 to ₹892 variant(s)
RositecTechnica Lab Pvt Ltd
401 variant(s)
ReglitDr Reddy's Laboratories Ltd
36 to ₹993 variant(s)
RosigonInvision Medi Sciences Pvt Ltd
37 to ₹552 variant(s)
EnselinTorrent Pharmaceuticals Ltd
48 to ₹1003 variant(s)

Expert advice for Rosiglitazone

  • Rosiglitazone has been withdrawn from the market due to an increased risk of heart attack and heart-related deaths.

Frequently asked questions for Rosiglitazone


Q. Can Rosiglitazone be used along with glimepiride in diabetes?

Rosiglitazone when added to Glimepiride in patients with diabetes mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood glucose control related to a reduction in the insulin resistance.

Q. How to use Rosiglitazone?

Rosiglitazone is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Pioglitazone acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.

Q. How does Rosiglitazone cause oedema?

Rosiglitazone increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Pioglitazone causes increased sodium and water reabsorption from the kidney that contributes to the oedema.

Q. How does Rosiglitazone cause heart failure?

Rosiglitazone can cause fluid retention and edema. Consequently, there is a lot of fluid in the body (fluid overload). As a result, it may precipitate heart failure (which worsens with fluid overload in those at risk).

Q. Can Rosiglitazone be used in depression?

Rosiglitazone, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study


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