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MDS (Oral Pathology & Microbiology), BDS
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MD (Pharmacology), MBBS
Last updated on:
14 Jun 2019 | 12:05 PM (IST)
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Retin 25 mg Injection

Prescription Required

Overview

Retin Injection side effects

Common
  • Sleepiness
  • Headache
  • Tiredness
  • Constipation
  • Diarrhea

How to use Retin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Retin Injection works

Retin 25 mg Injection is a H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Retin Injection related warnings

Alcohol
CAUTION
It is unsafe to consume alcohol with Retin 25 mg Injection. Alcohol use can increase acid secretion, acid reflux in food pipe causing heartburn and decreasing effect of this drug. Retin 25 mg Injection can also decrease alcohol breakdown and increase its level in blood.
Pregnancy
PROBABLY SAFE
Retin 25 mg Injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the fetus, however, there are limited human studies. Please consult your doctor.
Lactation
Retin 25 mg Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
SAFE
Retin 25 mg Injection does not usually affect your ability to drive.
Kidney
CAUTION
Retin 25 mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Retin 25 mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Retin 25 mg Injection should be used with caution in patients with liver disease. Dose adjustment of Retin 25 mg Injection may be needed. Please consult your doctor.

What if you miss a dose of Retin Injection?

If you miss a dose of Retin 25 mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Retin 25 mg Injection
Aciloc Injection
Cadila Pharmaceuticals Ltd
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Zinetac 25mg Injection
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₹1.98/ml of Injection
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Aciloc Injection
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₹1.55/ml of Injection
save 10%
Rantac 25mg Injection
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₹3.76/Injection
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Aztec 25mg Injection
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₹1.25/ml of Injection
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Expert Advice

  • Retin 25 mg Injection is a well tolerated and safe medicine with a very low incidence of side effects.
  • Take Retin 25 mg Injection before going to bed if you are taking this medicine once a day as it is very effective in controlling stomach acid released in the midnight.
  • If you are also taking an antacid, take it two hours before or after taking Retin 25 mg Injection.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Retin 25 mg Injection for two weeks or 14 days as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney or liver disease. Dose of your medicine may need to be adjusted.

Interaction with Drugs

Taking Retin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Vogmax
SERIOUS
Brand(s): Exeed, Metcalf, Estimet
SERIOUS
Brand(s): Indizole, Itracip, Itraspan
SERIOUS
Brand(s): Diadose
SERIOUS
Brand(s): Euroglip, Pridex MG, Glimpee
MODERATE
Brand(s): Stoin
MODERATE
Brand(s): Fungis, EF Z
MINOR

Patient Concerns

Questions Related to Retin

arrow
Suffering from acid reflux disease due to which pain in throat and right side of lower abdomen
Dr. Saurav Arora
Homeopathy
Dear sir for the time being you can take Robinia 30, 04 drops in half cup water and Nixocid tab 2 tab thrice daily for a month, but as this case needs supervision, discussion and examination you need to visit a homeopath so that he can discuss your case in detail, get some investigations, do examination and guide you accordingly,
I grind my teeth in sleep. What should i do?
Dr. Jyoti Kapoor Madan
Psychiatrist
Grinding your teeth or bruxism is a sleep related movement disorder.Doctors don't completely understand what causes bruxism. Possible physical or psychological causes may include: Emotions, such as anxiety, stress, anger, frustration or tension Aggressive, competitive or hyperactive personality type Abnormal alignment of upper and lower teeth (malocclusion) Other sleep problems, such as sleep apnea Response to pain from an earache or teething (in children) Stomach acid reflux into the esophagus An uncommon side effect of some psychiatric medications, such as phenothiazines or certain antidepressants A coping strategy or focusing habit Complication resulting from a disorder such as Huntington's disease or Parkinson's diseaseIn case it is causing damage to your teeth , visit a dentist.In case you have headache, facial pain, get a psychiatric evaluation
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FAQs

Q. Does Retin interfere with H. pylori test results?

A significant number of patients infected with Helicobacter pylori can have negative test results if they are using Retin as it interferes with the urea breath test, which is done to identify H. Pylori infection.

Q. Does Retin cause glaucoma?

Retin itself does not cause glaucoma. However, there are some rare reports that Retin can increase the intraocular pressure in patients who have glaucoma. Inform your doctor in case you have glaucoma or high intraocular pressure before taking this medicine.

Q. Can Retin be used to treat gastritis?

Yes, Retin can be used for the short-term treatment of gastritis. It helps by decreasing the amount of acid released into the stomach and relieving stomach pain and acid reflux.

Q. Is Retin safe?

Yes, Retin is safe if used at prescribed doses for the prescribed duration as advised by the doctor. However, there are some very common side effects that you can experience at the doses advised like nausea, abdominal pain, constipation, diarrhea, and flatulence.

Q. Is Retin an over the counter (OTC) drug?

No, Retin is not an over-the-counter product. It is a prescription medicine and is available only when prescribed by a physician.

Q. Can Vitamin B along with Retin?

Yes, Vitamin B can be taken along with Retin. No drug-drug interactions have been reported between this medicine and vitamin B.

Q. Why Retin is given along with vitamin B12?

Long term use of Retin can cause vitamin B12 deficiency as it decreases the acid secretion in the stomach which is required for the absorption of Vitamin B12. To prevent this deficiency, vitamin B12 may be advised by your doctor along with this medicine.

Q. Can a patient with hepatitis C take Retin?

Yes, a patient of hepatitis C can take Retin, however, this should be taken under medical supervision. Retin belongs to the group of drugs called H2 blockers which have been seen to increase the risk of hepatic encephalopathy in hepatitis C patients. So, this group of medicines should be used with caution in patients with underlying liver disease.

Q. Can I take Vitamin D along with Retin?

Yes, Vitamin D can be taken with Retin.

Q. Can the use of Retin cause headache?

Headache is reported as one of the common side effects of Retin. Inform your doctor in case you experience headache for a prolonged duration while taking Retin.

Q. What is the role of Retin in critically ill patients?

Retin may be used in critically ill patients to decrease stomach acid secretion and lower the risk of acid aspiration into the lungs. It also helps in decreasing stomach ulcers and gastrointestinal bleeding in these patients.

Q. What foods should be avoided when you are taking Retin?

You should preferably avoid foods that cause acidity and heartburn as they would aggravate your disease condition, for example: fried foods, prepared in butter or oil, fat rich foods, tomato-based foods and juices, caffeinated drinks like cola, tea, drinks from citrus fruits like lemon water or orange juice and alcohol-containing drinks.

Q. Can Retin be used for reflux esophagitis?

Yes, Retin is effective in the treatment of reflux esophagitis.

Q. Does Retin treat irritable bowel syndrome (IBS)?

Retin is not routinely used for the treatment of irritable bowel syndrome (IBS). It is given if there is associated dyspepsia or increased stomach acid secretion. IBS is managed with a combination of antispasmodics (to relieve stomach pain), laxatives (to relieve constipation), and anti motility drugs (to relieve diarrhea).

Q. Why is Retin given with cancer drugs?

Retin may be used for multiple reasons in cancer patients. It can lower stomach acid volume in patients undergoing chemotherapy to prevent aspiration and lower the risk of stomach ulceration and bleeding. According to some studies, Retin can potentiate white blood cell against cancer cells and can be helpful in the treatment of cancer.

Q. Is Retin used to treat nausea?

Retin is used for the treatment of acidity, heartburn, intestinal ulcers and stomach ulcers and can help in providing relief in nausea that may happen due to acid reflux. It is not used to treat nausea due to any other cause. Rather, nausea is one of the most common side effects of Retin.

Q. What is the benefit of taking Retin with pantoprazole?

Both Retin and pantoprazole lower gastric acid secretion, however, they work by different mechanisms. If you have been advised to take pantoprazole, you can also take Retin initially for rapid relief of heartburn and acid reflux as pantoprazole may take a few days to show its effect and provide relief.

Q. Can I take Retin with pain killers?

Yes, Retin can be taken with painkillers. Retin can help to prevent painkillers induced gastritis and stomach ulcers by decreasing the production of acid in the stomach. Moreover, there are no clinically significant interactions of Retin with painkillers.

Q. What are the serious side effects associated with the use of Retin?

Some serious side effects associated with the use of Retin are bone marrow hypoplasia (decreased formation of blood cell components), anaphylactic shock (severe allergic reactions) sinus bradycardia (lowering of heart rate) and acute pancreatitis (inflammation of the pancreas).

Q. Why does Retin cause diarrhea?

Use of Retin lowers the natural stomach acid which normally helps to kill bacteria. So, use of Retin leads to overgrowth of the harmful bacteria like clostridium difficile which can cause diarrhea. This is known as clostridium difficile–associated diarrhea (CDAD). Inform your doctor if you have loose stools many times in a day and for many days with stomach cramps and fever.

Q. Is Retin effective?

Retin would be effective only if used for the right indication in the dose and for the duration as advised by the doctor. In case you do not find any change in your disease condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.

Q. Can I smoke while taking Retin?

It is better to avoid cigarette smoking when you are taking Retin. As studies have shown that the effectiveness of Retin is lower in smokers compared to non-smokers. Moreover, smoking may add to gastric problems leading to more production of gastric acid.

Q. Can the use of Retin cause iron deficiency?

Yes, use of Retin can cause iron deficiency and a decrease in hemoglobin levels as it decreases the acidic environment of the stomach needed for the absorption of iron. However, there are no recommendations on the regular monitoring of iron levels or taking iron supplements when the patient is taking Retin but you can maintain good dietary nutrition so that no deficiency occurs.

Q. Is there any known role of Retin before surgery?

Retin is given as a part of pre-anesthetic medication before surgery to decrease the stomach acid secretion so that stomach acid is not aspirated into the lungs during surgery as this may complicate or delay the procedure.

Q. Does Retin cause flatulence (gas or bloating)?

Flatulence (gas) has been reported as a common side effect of Retin. Although it would be mild to moderate in nature and it goes away once you stop taking Retin.

Q. Is Retin an antihistaminic drug?

Yes, Retin is an antihistaminic drug. It acts on histamine receptors in the stomach and blocks the action of a chemical messenger histamine (causes acid secretion in stomach) and hence decreases the acid production in the stomach.

Q. Can the use of Retin cause constipation?

Yes, the use of Retin can cause constipation. It is one of the common side effect seen with Retin. Taking high fiber diet and plenty of fluids can help in relieving constipation and can also help in decreasing acidity.

Q. Is Retin useful in the prevention of painkiller (NSAID) induced gastric ulcers?

Yes, Retin is useful for the prevention of painkiller (non-steroidal anti-inflammatory drug - NSAID) induced gastric ulcers. These may cause dull pain in the stomach, sudden weight loss, loss of appetite, nausea, vomiting or bloating. Avoid stress and spicy foods as they can make your symptoms worse.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Wallace JL, Sharkey KA. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: The McGraw-Hill Companies, Inc.; 2011. [Accessed 24 Jan. 2019] (online) Available from:External Link
  2. Ranitidine. Triangle Park, NC: GlaxoSmithKline; April 2009. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. U.S. National Library of Medicine. Ranitidine. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
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