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Pazopanib is used to treat advanced kidney cancer and advanced soft tissue sarcoma (cancer that affects the supportive tissues of the body) in patients who have received prior chemotherapy (anticancer drug therapy).

How it works

Pazopanib is an anticancer drug that belongs to class of medicines called tyrosine kinase inhibitors. It works by inhibiting an enzyme protein kinase thereby preventing the activity of proteins involved in growth and spread of cancer cells.

Common side effects

Acne-like rash, Facial swelling, Allergic reaction, Lip swelling, Muscle pain, Joint pain, Change in color of hair, Constipation, Diarrhoea, Altered taste, Hair loss, Heartburn, Lightening of skin color, Nail disorder, Rash, Weakness, Depression, Weight loss


Expert advice

  • Do not start pazopanib and consult your doctor if you have heart or liver disease, heart failure or attack, lung collapse, blood disorders, thyroid problems, stomach or bowel problems, high blood pressure, are pregnant or breastfeeding.
  • Tell your doctor if you suffer from shortness of breath or cough, pass blood in stool or urine, cough blood, or suffer from stomach pain, blurred or impaired vision or you are going to have an operation while on pazopanib treatment.
  • Pazopanib is not recommended in children under 18 years of age.
  • Take effective contraceptive measures while on pazopanib treatment.
  • Do not drive or operate machinery as pazopanib can make you dizzy, tired or weak.

Frequently asked questions


Q. Is pazopanib a chemotherapy drug, cytotoxic?
Pazopanib is not a chemotherapy drug. It is a cytotoxic drug.
Q. Is pazopanib FDA approved?
Pazopanib is FDA approved.
Q. How quickly does pazopanib work?
Pazopanib starts working in around 2-4 hours.

Q. How long does pazopanib work?
 The effect lasts for about 30 hours.

Content on this page was last updated on 19 October, 2016, by Dr. Varun Gupta (MD Pharmacology)