Information about Pazopanib

Pazopanib Uses

Pazopanib is used in the treatment of kidney cancer and soft tissue sarcoma.

How Pazopanib works

Pazopanib is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (tyrosine kinase) that are responsible for the proliferation of the cancerous cells. It also restricts the growth of new blood vessels within the tumor. This is how it works against cancer.

Common side effects of Pazopanib

Headache, Diarrhea, High blood pressure, Decreased appetite, Taste change, Breathlessness, Low blood platelets, Decreased level of thyroid hormones, Insomnia (difficulty in sleeping), Infection, Hair loss, Nosebleeds, Decreased white blood cell count (neutrophils), Decreased white blood cell count (lymphocytes), Decreased phosphate level in blood, Dehydration, Peripheral sensory neuropathy, Blurred vision, Hot flushes, Venous thromboembolism, Voice change, Coughing up blood, Increased bilirubin in the blood, Liver toxicity, Hypopigmentation
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Written By
MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
29 Jun 2022 | 04:52 AM (UTC)

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Available Medicine for Pazopanib

VotrientGlaxo SmithKline Pharmaceuticals Ltd
8685 to ₹173703 variant(s)
BiopanibBiocon
3500 to ₹66002 variant(s)
PazinibHetero Healthcare Limited
2200 to ₹43002 variant(s)
PazonatNatco Pharma Ltd
6500 to ₹90002 variant(s)
PazoleeAdmac Pharma Ltd
7995 to ₹159002 variant(s)
PazobriteTorrent Pharmaceuticals Ltd
5211 to ₹104224 variant(s)
PazibGlenmark Pharmaceuticals Ltd
2000 to ₹38002 variant(s)
PazociCipla Ltd
5995 to ₹99952 variant(s)
PazocamMedicamen Biotech Ltd
2700 to ₹45002 variant(s)
PazolongMSN Laboratories
3900 to ₹64782 variant(s)

Frequently asked questions for Pazopanib

Pazopanib

Q. Is Pazopanib a chemotherapy medicine?

Pazopanib is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazopanib works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

Q. How should I take Pazopanib?

Pazopanib should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

Q. Can Pazopanib be taken with food?

Pazopanib should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

Q. How will I know if Pazopanib is helping me?

The duration for which you have to continue taking Pazopanib varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. Are there any food restrictions while I’m taking Pazopanib?

Yes, it is best to avoid grapefruit and grapefruit juice while on Pazopanib, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

Q. How long I have to take Pazopanib?

The duration for which you have to continue taking Pazopanib varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

Q. What is the most important information I need to know about Pazopanib?

Pazopanib may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Votrient. After you start taking Votrient, you may need to take those lab tests at weeks 3, 5, 7 and 9 and then at months 3 and 4. Your doctor may also prescribe additional tests if necessary. Periodic testing should then continue after 4 months.

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