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    Pazopanib

    Information about Pazopanib

    Pazopanib uses

    Pazopanib is used in the treatment of kidney cancer and soft tissue sarcoma.

    How pazopanib works

    Pazopanib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

    Common side effects of pazopanib

    Headache, Nausea, Vomiting, Musculoskeletal (bone, muscle or joint) pain, Fatigue, Change in color of hair, Diarrhea, High blood pressure, Decreased appetite, Weight loss, Taste change, Abnormal skin pigmentation, Hair discolouration, Tumor pain, Shortness of breath
    Content Details
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    Written By
    Dr. Anuj Saini
    MMST, MBBS
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    Reviewed By
    Dr. Ashish Ranjan
    MD (Pharmacology), MBBS
    Last updated on:
    19 Jul 2019 | 04:11 PM (IST)
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    Available Medicine for Pazopanib

    • ₹7903 to ₹15805
      Glaxo SmithKline Pharmaceuticals Ltd
      2 variant(s)

    Expert advice for Pazopanib

    • Pazopanib is used for the treatment of thyroid cancer.
    • Take it with or without food, preferably at the same time each day.
    • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
    • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
    • Do not take it with medication lowering the stomach acid (such as antacids, H2 blockers including ranitidine), as it may affect the working of medicine.
    • It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
    • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
    • Inform your doctor about the consumption of Pazopanib before going for surgical procedure.
    • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
    • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

    Frequently asked questions for Pazopanib

    Pazopanib

    Q. Is Pazopanib a chemotherapy medicine?

    Pazopanib is not a conventional chemotherapy medicine. It belongs to a class of medicine called a protein kinase inhibitor. Pazopanib works by preventing the activity of proteins that are involved in the growth and spread of cancer cells.

    Q. How should I take Pazopanib?

    Pazopanib should be taken orally by mouth once a day or as directed by your doctor. Swallow the tablets whole with water, do not break or crush the tablets. This affects the way the medicine is absorbed and may increase the chance of side effects.

    Q. Can Pazopanib be taken with food?

    <br>Pazopanib should be taken on an empty stomach, at least 1 hour before or 2 hours after food. If it is taken with food, the dosage may need to be increased. Doing this will in turn cause more side effects.

    Q. How will I know if Pazopanib is helping me?

    The duration for which you have to continue taking Pazopanib varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

    Q. Are there any food restrictions while I’m taking Pazopanib?

    Yes, it is best to avoid grapefruit and grapefruit juice while on Pazopanib, as it may affect how the medicine works in your body. Ask your doctor about any additional foods you should avoid.

    Q. How long I have to take Pazopanib?

    The duration for which you have to continue taking Pazopanib varies from person to person. The doctor monitors you closely and will be able to better estimate how long the medicine needs to be taken. Do not stop taking it without telling your doctor. It needs to be taken as long as it is effective and you can tolerate it.

    Q. What is the most important information I need to know about Pazopanib?

    Pazopanib may cause severe or life-threatening liver damage. Inform your doctor if you have or had liver disease. If you experience any of the following symptoms such as discoloration of the skin or eyes (yellowing), dark urine, extreme tiredness, nausea, vomiting, loss of appetite, pain in the upper right part of the stomach, or unusual bleeding or bruising, call your doctor immediately. Your doctor may ask you to take some lab tests before you start taking Pazopanib, at weeks 3, 5, 7 and 9, then at months 3 and 4, with additional tests as clinically indicated. Periodic testing should then continue after 4 months.

    Content on this page was last updated on 19 July, 2019, by Dr. Varun Gupta (MD Pharmacology)