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Aciloc Injection

Ranitidine (25mg)
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Aciloc Injection is a medicine that reduces the amount of excess acid made by your stomach. It is used in people who are hospitalized to treat certain conditions in which the stomach produces too much acid.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 Apr 2026 | 11:10 AM (IST)
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General Information

The content is shown in English
Aciloc Injection image
Aciloc Injection image
Aciloc Injection image
Aciloc Injection image

Product introduction

Aciloc Injection is also used to treat ulcers (sores in the lining of the stomach or intestine) which did not get cured with other medications. It is generally administered by a doctor or a nurse. Do not self-administered this medicine at home. The dose will depend on what you are being treated for. Follow the advice of your doctor while taking the medicine. This medicine should relieve indigestion and heartburn within a few hours. You may only need to use it for a short time when you have symptoms. If you are getting the injection to prevent ulcers and other conditions you may need to take it for longer a period. You should keep using it regularly to prevent problems from happening in the future. You may be able to help improve your symptoms by eating smaller meals more often and avoiding spicy or fatty foods.

Most people do not experience any side effects while taking the medicine. However, some people may experience headache, constipation, feeling drowsy or tired, and diarrhea. These side effects are usually mild and will go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.

Before taking it, you should tell your doctor if you have any kidney or liver problems. Also tell your doctor what other medicines you are taking as some may affect, or be affected by, this medicine. This medicine is usually considered safe to take during pregnancy and breastfeeding if it has been prescribed by a doctor. Avoid drinking alcohol as this can increase the amount of acid in your stomach, and make your symptoms worse.

Uses of Aciloc Injection

Benefits of Aciloc Injection

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic condition which is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your oesophagus and mouth. Aciloc Injection reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.

Some simple lifestyle changes can help stop or reduce heartburn. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3 to 4 hours of going to bed.
Peptic ulcer disease
Stomach ulcers are usually caused by using non-steroidal anti-inflammatory drugs (NSAIDs) or by bacteria called Helicobacter pylori. They both break down the stomach’s defence against the acid it produces to digest food. This damages the stomach and allows an ulcer to form. Aciloc Injection may be used to treat these ulcers. It reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines depending on what caused the ulcer. It may also be prescribed to prevent stomach ulcers from forming by reducing the amount of acid.

Side effects of Aciloc Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aciloc
  • Diarrhea
  • Headache
  • Gastrointestinal disturbance

How to use Aciloc Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Aciloc Injection works

Aciloc Injection is a histamine H2 receptor blocker that reduces the amount of acid made in the stomach. It relieves acid-related indigestion and heartburn.

Quick tips

  • It is given as an injection into the veins under the supervision of the doctor.
  • If you are also taking other medications to treat acidity (e.g., antacid), take them 2 hours before or after taking Aciloc Injection.
  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
  • Inform your doctor if you do not feel better after taking Aciloc Injection for 2 weeks as you may be suffering from some other problems.
  • Inform your doctor if you have ever been diagnosed with kidney disease as dose of your medicine may need to be adjusted.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aciloc Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Aciloc Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Aciloc Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

SAFE
Aciloc Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Aciloc Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Aciloc Injection in patients with liver disease.

Interaction with drugs

Taking Aciloc with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Dasatinib (Oral Route)

Ranitidine may reduce blood levels and efficacy of Dasatinib. Ranitidine may reduce blood levels and efficacy of Dasatinib.
Severe

Pazopanib (Oral Route)

Ranitidine may reduce blood levels of Pazopanib. Ranitidine may reduce blood levels of Pazopanib.
Moderate

Cefpodoxime Proxetil (Oral Route)

To take Cefpodoxime Proxetil, ensure a gap of at least 2 hours before taking Ranitidine. Ranitidine may reduce blood levels of Cefpodoxime Proxetil.
Moderate

Memantine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Phenytoin (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

There is limited data available on whether Aciloc Injection can be used for the long term or not, but it is a relatively safe medicine. You should take it for the duration advised by your doctor. Do not take over-the-counter Aciloc Injection for longer than 2 weeks unless advised by your doctor.
Aciloc Injection would be effective only if used for the right indication in the dose and the duration as advised by the doctor. In case you do not find any change in your condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.
Avoid taking aspirin and other painkillers used to treat arthritis, period pain, or headache. These medicines may irritate the stomach and make your condition worse. Contact your doctor who may suggest other medicines. Avoid coffee, tea, cocoa, and cola drinks because these contain ingredients that may irritate your stomach. Eat smaller, more frequent meals. Eat slowly and chew your food carefully. Try not to rush while having meals. You should stop or cut down on smoking.
Aciloc Injection starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.
Aciloc Injection may be taken with or without food. It can be taken once daily before bedtime or twice daily in the morning and before bedtime, as recommended.
Aciloc Injection starts working as fast as 15 minutes from when it is given. Its effect is seen to last all day or all night.
Aciloc Injection and Omeprazole belong to different groups of medicines. While Aciloc Injection belongs to histamine H2 antagonists group, Omeprazole belongs to proton pump inhibitors group. These medicines (Aciloc Injection and Omeprazole) work by reducing the amount of acid made by the stomach, to give relief of symptoms and allow healing to take place.
Alcohol does not interfere with the working of Aciloc Injection. But, you should avoid taking alcohol as it may further damage the stomach, delaying your recovery.
Aciloc Injection may have some serious side effects, but these are rare. These side effects may include hives, skin rash, itching, hoarseness, and difficulty in breathing or swallowing. Another serious symptom may be swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs. Inform your doctor in case you notice any of the mentioned symptoms.
Avoid taking aspirin and other painkillers used to treat arthritis, period pain, or headache. These medicines may irritate the stomach and make your condition worse. Contact your doctor who may suggest other medicines. Avoid coffee, tea, cocoa, and cola drinks because these contain ingredients that may irritate your stomach. Eat smaller, more frequent meals. Eat slowly and chew your food carefully. Try not to rush while having meals. You should stop or cut down on smoking.
There is limited data available on whether Aciloc Injection can be used for the long term or not, but it is a relatively safe medicine. You should take it for the duration advised by your doctor. Do not take over-the-counter Aciloc Injection for longer than 2 weeks unless advised by your doctor.
Aciloc Injection would be effective only if used for the right indication in the dose and the duration as advised by the doctor. In case you do not find any change in your condition while taking this medicine, please talk to your doctor. Do not change the dose or stop taking the medicine without consulting your doctor.

Fact Box

Chemical Class

Heterocyclic amines

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Histamine Type-2 Receptor Antagonists (H2 Blockers)
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100% genuine products
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No contact delivery
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Fully sanitized facilities
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User feedback

Once A Day
39%
Once A Month
22%
Twice A Day
16%
Once A Week
11%
Twice A Month
7%
Thrice A Day
4%
Four Times A Day
1%
Others
50%
Acidity
50%
Excellent
89%
Average
11%
Headache
100%
With food
100%
Average
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cadila Pharmaceuticals Ltd
Address: Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Aciloc Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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