


Retefuse 18mg Injection
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 05:15 PM (IST)
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General Information



Product introduction
Retefuse 18mg Injection is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment.
This medicine may increase your risk of bleeding, so it is better to be careful while shaving, cutting nails, or using sharp objects. Treatment with this drug can also cause nausea, vomiting, decreased blood pressure, and injection site bleeding.
This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Retefuse 18mg Injection including if you have had a head injury or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.
Uses of Retefuse Injection
Benefits of Retefuse Injection
Retefuse 18mg Injection dissolves harmful blood clots that cause heart attack (if they are in the heart). They also dissolve clots that form in other blood vessels. This means that blood can again start to flow freely through your body. This medicine will, therefore, reduce both the damage caused by, and the risk of dying from a heart attack. The sooner the injection is given, the greater are the chances of recovery.
Side effects of Retefuse Injection
- Bleeding disorder
- Nausea
- Vomiting
- Decreased blood pressure
- Injection site bleeding
How to use Retefuse Injection
How Retefuse Injection works
All substitutes for Retefuse 18mg Injection
Quick tips
- It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
- Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising.
- Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.

Liver
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.
Interaction with drugs
Cilostazol (Oral Route)
Apixaban (Oral Route)
Tranexamic Acid (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 384.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1208.




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Lab tests offered by us
- CBC (Complete Blood Count)
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- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
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- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)














