Product introduction
Retefuse 18mg Injection is a medicine that dissolves clots that have formed in blood vessels. It is used to treat a heart attack. It is known as a thrombolytic or “clot-busting” drug. This medicine restores the blood flow to the affected tissue, thereby preventing tissue death.
Retefuse 18mg Injection is an injectable drug, given directly into a vein and it is given by a doctor as soon as possible after the first signs of a heart attack. Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely. You may be given another medicine to stop blood clotting at the same time or after the treatment.
This medicine may increase your risk of bleeding, so it is better to be careful while shaving, cutting nails, or using sharp objects. Treatment with this drug can also cause nausea, vomiting, decreased blood pressure, and injection site bleeding.
This drug needs to be administered with care by an expert and is not suitable for everyone. There is a long list of situations where you will not be given Retefuse 18mg Injection including if you have had a head injury or surgery on your brain or spinal cord and any current bleeding anywhere in your body. Your healthcare team will need to know a lot about your medical history before giving you this medicine.
Uses of Retefuse Injection
Benefits of Retefuse Injection
In Heart attack
Retefuse 18mg Injection dissolves harmful blood clots that cause heart attack (if they are in the heart). They also dissolve clots that form in other blood vessels. This means that blood can again start to flow freely through your body. This medicine will, therefore, reduce both the damage caused by, and the risk of dying from a heart attack. The sooner the injection is given, the greater are the chances of recovery.
Side effects of Retefuse Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Retefuse
- Bleeding disorder
- Nausea
- Vomiting
- Decreased blood pressure
- Injection site bleeding
How to use Retefuse Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Retefuse Injection works
Retefuse 18mg Injection is a thrombolytic medication. It works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Retefuse 18mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Retefuse 18mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
SAFE IF PRESCRIBED
Retefuse 18mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving
CONSULT YOUR DOCTOR
It is not known whether Retefuse 18mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Retefuse 18mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.
Liver
UNSAFE
Retefuse 18mg Injection is unsafe to use in patients with liver disease and should be avoided.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.
Use of Retefuse 18mg Injection is not recommended in patients with severe kidney disease.
What if you forget to take Retefuse Injection?
If you miss a dose of Retefuse 18mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Retefuse 18mg Injection
₹27640/Injection
Retefast 18mg Injection
Cipla Ltd
₹30937.5/injection
1% costlier
Quick tips
- It should be given as soon as possible (within 12 hours) after the onset of a heart attack or within 4.5 hours of onset of stroke.
- Let your doctor know immediately if you develop any nosebleeds, gum bleeding, black or tarry stools, or bruising.
- Do not discontinue the medicines started after this injection as it may increase your chances of having another heart attack or stroke.
Fact Box
Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Plasminogen Activators- Thrombolytics
Interaction with drugs
Taking Retefuse with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Apixaban with Reteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Reteplase may increase the effect of Apixaban.
C
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Concurrent use may increase the risk of bleeding.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Tranexamic Acid may block the action of Reteplase.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Concurrent use may increase the risk of internal bleeding.
Do not consume Tirofiban with Reteplase. If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Concurrent use may increase the risk of bleedi
User feedback
What are you using Retefuse Injection for?
Heart attack
100%
How much was the improvement?
Excellent
47%
Average
30%
Poor
23%
What were the side-effects while using Retefuse 18mg Injection?
Decreased blo*
40%
Injection sit*
20%
No Side Effec*
20%
Nausea
20%
*Decreased blood pressure, Injection site bleeding, No Side Effect
How do you take Retefuse Injection?
With food
50%
Empty stomach
33%
With or witho*
17%
*With or without food
Please rate Retefuse 18mg Injection on price
Expensive
53%
Average
33%
Not Expensive
13%
FAQs
How is Retefuse 18mg Injection administered?
Retefuse 18mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Retefuse 18mg Injection.
Is Retefuse 18mg Injection safe?
Retefuse 18mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Can the use of Retefuse 18mg Injection increase the risk of bleeding?
Yes, Retefuse 18mg Injection can increase the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
What medicines should I avoid while taking Retefuse 18mg Injection?
Retefuse 18mg Injection can interact with several medicines. If you are already taking Retefuse 18mg Injection, do not take any other medicine without talking to your doctor.
When will I feel better after taking Retefuse 18mg Injection?
Retefuse 18mg Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Retefuse 18mg Injection. This does not mean that the medicine is not working, therefore keep taking this medicine as prescribed.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 384.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1208.
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
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NOT FOR SALE
We do not facilitate sale of this product at present