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Reteplase is used for heart attack, pulmonary embolus (blood clot in lungs) and ischemic stroke (decreased blood supply to brain)

How it works

Reteplase belongs to class of medicines called thrombolytics. It works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin), thereby preventing heart failure and death in patients who previously had heart attack.

Common side effects

Abnormal heart rhythm, Dizziness, Muscle pain, Cerebral hemorrhage, Allergic reaction, Injection site inflammation, Slow growth in children and teenagers, Cardiac adverse reaction, Altered cholesterol level, Hormone imbalance, Fever, Anemia, Chills, Bleeding, Nose bleed, Gastrointestinal bleeding, Decreased blood pressure

Available Medicine

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    Abbott India Ltd
    1 variant(s)
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    Lupin Ltd
    2 variant(s)
  • ₹28333
    Emcure Pharmaceuticals Ltd
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    Reliance Life Sciences
    1 variant(s)

Expert advice

  • Consult your doctor if you are suffering from any of the following: cerebrovascular disease, high blood pressure, gastrointestinal or genitourinary bleeding within 10 days, narrowing of the valves on the left side of the heart (mitral stenosis) with fast uncontrolled heartbeat (atrial fibrillation), inflammation of a vein caused by a blood clot (septic thrombophlebitis) or occluded arteriovenous cannula at seriously infected site.
  • You will be carefully evaluated for bleeding risk during treatment with reteplase.
  • Seek immediate medical advice if you feel palpitations or an irregular heartbeat after the administration of reteplase.
  • Take necessary precautions if your age is over 75 years as you are at high risk of bleeding.
  • Do not take reteplase along with heparin.
  • Stop taking reteplase and seek immediate medical attention if you develop severe allergic reaction.
  • Use of reteplase is not recommended in children.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions



What is reteplase drug class?
Reteplase belongs to class of medicines called thrombolytics


What is reteplase used for?
Reteplase is used to improve heart function and prevent congestive heart failure or death in people who have had a heart attack


How does reteplase work?
Reteplase works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin).

Content on this page was last updated on 09 February, 2017, by Dr. Varun Gupta (MD Pharmacology)