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Reteplase

INFORMATION

Uses

Reteplase is used for heart attack, pulmonary embolus (blood clot in lungs) and ischemic stroke (decreased blood supply to brain).

How it works

Reteplase belongs to class of medicines called thrombolytics. It works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin), thereby preventing heart failure and death in patients who previously had heart attack.

Common side effects

Vomiting, Nausea, Abnormal heart rhythm, Hormone imbalance, Allergic reaction, Slow growth in children and teenagers, Altered cholesterol level, Anemia, Cardiac adverse reaction, Cerebral hemorrhage, Dizziness, Gastrointestinal bleeding, Decreased blood pressure, Muscle pain, Chills, Fever, Injection site inflammation

AVAILABLE MEDICINE

Expert advice

  • Consult your doctor if you are suffering from any of the following: cerebrovascular disease, high blood pressure, gastrointestinal or genitourinary bleeding within 10 days, narrowing of the valves on the left side of the heart (mitral stenosis) with fast uncontrolled heartbeat (atrial fibrillation), inflammation of a vein caused by a blood clot (septic thrombophlebitis) or occluded arteriovenous cannula at seriously infected site.
  • You will be carefully evaluated for bleeding risk during treatment with reteplase.
  • Seek immediate medical advice if you feel palpitations or an irregular heartbeat after the administration of reteplase.
  • Take necessary precautions if your age is over 75 years as you are at high risk of bleeding.
  • Do not take reteplase along with heparin.
  • Stop taking reteplase and seek immediate medical attention if you develop severe allergic reaction.
  • Use of reteplase is not recommended in children.
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Frequently asked questions

Reteplase

Q.What is reteplase drug class?
Reteplase belongs to class of medicines called thrombolytics

Q.What is reteplase used for?
Reteplase is used to improve heart function and prevent congestive heart failure or death in people who have had a heart attack

Q.How does reteplase work?
Reteplase works by dissolving the blood clots (splitting of endogenous plasminogen to plasmin).


Content on this page was last updated on 30 November, 2016, by Dr. Varun Gupta (MD Pharmacology)