Rapamune 1mg Tablet

Pfizer Ltd

Composition for Rapamune 1mg Tablet

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Primarily used for

Transplant rejection of kidney
10 tablets in 1 strip

Medicine Overview of Rapamune Tablet


Uses of Rapamune Tablet

Rapamune 1mg Tablet is used in transplant rejection of kidney.

Side effects of Rapamune Tablet


Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia, Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.


How to use Rapamune Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rapamune 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Rapamune Tablet works

Rapamune 1mg tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

In Depth Information on Rapamune Tablet

Expert advice for Rapamune Tablet

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Special precautions for Rapamune 1mg Tablet
Interaction with alcohol is unknown. Please consult your doctor.
Rapamune 1mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Rapamune 1mg Tablet is probably usafe to use during lactatio
n. Limited human data suggests that the drug could represent a significant risk to the baby.
Rapamune 1mg Tablet does not usually affect your ability to drive.
Rapamune 1mg Tablet is safe to use in patients with kidney d
isease. No dose adjustment of Rapamune 1mg Tablet is recommended.
Rapamune 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Rapamune 1mg Tablet may be needed. Please consult your doctor.

Dose adjustment is not recommended in patients with mild to moderate liver disease.
Severely interacts with other drugs like
Azibey 200mg Suspension, Azivent 500mg Tablet, Azita 500mg Tablet, Itragreat 200mg Capsule
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Patient Concerns

Frequently asked questions for Rapamune 1mg Tablet

Frequently asked questions for Sirolimus

Rapamune is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Rapamune is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Rapamune is a cytotoxic agent
The Rapamune-eluting stent is a metal stent coated with 140 µg/cm2 of Rapamune blended with synthetic polymers. After stent implantation, Rapamune is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Rapamune causes hair loss
Rapamune alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.

User Submitted Feedback For Rapamune 1mg Tablet

Survey Participants: 1
“The following are the results of on-going survey on 1mg.com for Rapamune 1mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”

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