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Rapamune 1mg Tablet

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Pfizer Ltd

Composition for Rapamune 1mg Tablet

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Primary uses of Rapamune 1mg Tablet

Prevention of kidney transplant rejection
MRP
3709.67
₹370.97/Tablet
10 tablets in 1 strip
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Medicine Overview of Rapamune Tablet

uses

Uses of Rapamune Tablet

Rapamune 1mg Tablet is used to prevent prevention of kidney transplant rejection.
uses

Rapamune Tablet side effects

Common

Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Reduced blood platelets, Increased heart rate, Decreased white blood cell count, Anemia (low number of red blood cells), Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.

uses

How to use Rapamune Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rapamune 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Rapamune Tablet works

Rapamune 1mg Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

In Depth Information on Rapamune Tablet

Expert advice for Rapamune Tablet

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Rapamune Tablet related warnings
Special precautions for Rapamune Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Rapamune 1mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Rapamune 1mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
SAFE
Rapamune 1mg Tablet does not usually affect your ability to drive.
Kidney
SAFE
Rapamune 1mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Rapamune 1mg Tablet is recommended.
Liver
Rapamune 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Rapamune 1mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

Patient Concerns

User Submitted Feedback For Rapamune 1mg Tablet

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“The following are the results of on-going survey on 1mg.com for Rapamune 1mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”

Frequently asked questions about Rapamune Tablet

Frequently asked questions about Sirolimus

Rapamune is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Rapamune is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Rapamune is a cytotoxic agent
The Rapamune-eluting stent is a metal stent coated with 140 µg/cm2 of Rapamune blended with synthetic polymers. After stent implantation, Rapamune is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Rapamune causes hair loss
Rapamune alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Severely interacts with other drugs like
Taking Rapamune with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Rapamune with Clarithromycin
LIFE-THREATENING
Medicines with composition Clarithromycin: Clarimac, Klarim, Cloff, Clarital, Truclar, Claricin, Bioclar, Claribid, Clarie, C Cin
Rapamune with Varicella Vaccine
LIFE-THREATENING
Medicines with composition Varicella Vaccine: Biovac V
Rapamune with Voriconazole
LIFE-THREATENING
Medicines with composition Voriconazole: Vosicaz, Vorizol, Voraze, Rextro, Vhope, Vonaz, Vocozo, Voritek, Voritrop, Vorifit, Vorzu
LIFE-THREATENING
Medicines with composition Rubella (German Measles): Rubella, R-VAC
Rapamune with Rifampicin
LIFE-THREATENING
Medicines with composition Rifampicin: Monocin, Rifacept, R-Cin, Montomycin, Ticin
LIFE-THREATENING
Medicines with composition Rotavirus Vaccine Live Attenuated: Rotarix
Rapamune with Erythromycin
LIFE-THREATENING
Medicines with composition Erythromycin: Althrocin, Eryster, Eryspic, Elthrocin, Etomin, Erythrocin, Erypal, Erythrokem, Agrocin, Eltocin, Eryspans
Rapamune with Spiramycin
LIFE-THREATENING
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox
Rapamune with Nimodipine
SERIOUS
Medicines with composition Nimodipine: Nimpod, Nimocer, Vasotop
Rapamune with Benidipine
SERIOUS
Medicines with composition Benidipine: Caritec
Rapamune with Danazol
SERIOUS
Medicines with composition Danazol: Gonablok, Ladogal, Endometryl
Rapamune with Ritonavir
SERIOUS
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Rapamune with Indinavir
SERIOUS
Medicines with composition Indinavir: Indivan
Rapamune with Lercanidipine
SERIOUS
Medicines with composition Lercanidipine: Lotensyl, Lervasc
Rapamune with S-Amlodipine
SERIOUS
Medicines with composition S-Amlodipine: S-Amcard, Esam, Big Dvr
Rapamune with Ketoconazole
SERIOUS
Medicines with composition Ketoconazole: Hyporal
Rapamune with Nifedipine
SERIOUS
Medicines with composition Nifedipine: Calnif, Depicor, Calbloc, Calcigard, Nicardia, Nepin, Nefidipine, Cardipin, Depin, Nifelat, Nifedine, Nifidip
Rapamune with Imidapril
SERIOUS
Medicines with composition Imidapril: Tanatril
Rapamune with Fosphenytoin
SERIOUS
Medicines with composition Fosphenytoin: Fosphen, Fosentin
Rapamune with Itraconazole
SERIOUS
Medicines with composition Itraconazole: Itrasig, Itracan, Candiforce, Canditral, Onitraz, Iycotizol, Itrasys, Syntran, Nixitral, I-Tyza, Afderm, Itraderm
Rapamune with Perindopril
SERIOUS
Medicines with composition Perindopril: Perihart
Rapamune with Posaconazole
SERIOUS
Medicines with composition Posaconazole: Noxafil
Rapamune with Phenytoin
SERIOUS
Medicines with composition Phenytoin: Episol, Neptoin, C-Toin, Eptoin
Rapamune with Enalapril
SERIOUS
Medicines with composition Enalapril: Envas, Minipril, EL, Enapril, Hytrol, Bql, Normace, Canvas, Tenam, Nuril, Enace, Enam, Encardil, Myoace, Vasopril
One of the following vendor pharmacies will deliver Rapamune 1mg Tablet: SYN, PWN, DVH, MAX, HPC, PEN, HBV, MMS, DFP, OLT, HGI, SLN, HEX, RUS, JSL, ABP, TOM, ATL, PLT, QTM, BAL, MAM, WSI, BSN, RHL, RSA, SBA, KHC, CLT, PPR, BIO, BDN, PRN, OHM, USF, SAF, PMA, STA, MPC, ZVP, MAK, SWP, NDP, SGH, MLC, GBL, SDM, THP, KHH, RWP, BHP, VDH, QLF, OIP, KMC, 9T9, SHD, PNT, MDO, HTS, AYU, BBS, SWA, ENP, IPL, ANT, EVP, NXG, PVP, RDH, NTB, JVN, AGT, TFP, BHM, NAS, SHP, OWP, VRS, JIV, PTI, INC, BLE, NVL, RPI, BMJ, DGN, GHR, AMR, ATP, HNP, AYM, NSL, DAO, SJP, NVY, DPL, IAD, LCC, BAP, AAR, JVO, GTC, EMB, HAT, FGH, ADT, HZF, TNH, MSD, RDR, ZEL, SGC, HSP, GNC, GPT, DYG, HMP, NNH, RKS, BTM, LHA, DLP, EQN, WHL, P2P, RJH, RSS, GPP, SVH, DHR, TRP, ESY, AAY, VNS, MDH, ARD, SHC, RHW, UMP, RPP, HIP, GTK, SRG, SCH, SBL, SSA, DPP

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