Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siropan 1 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Siropan 1 mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.
You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Siropan 1 mg Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Siropan 1 mg Tablet is probably unsafe to use during lactation.
Limited human data suggest that the drug could represent a significant risk to the baby.
Siropan 1 mg Tablet does not usually affect your ability to drive.
Siropan 1 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Siropan 1 mg Tablet is recommended.
Siropan 1 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Siropan 1 mg Tablet may be needed. Please consult your doctor. Dose adjustment is not recommended in patients with mild to moderate liver disease.
“The following are the results of on-going survey on 1mg.com for Siropan 1 mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
The Siropan-eluting stent is a metal stent coated with 140 µg/cm2 of Siropan blended with synthetic polymers. After stent implantation, Siropan is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month