Siropan 1mg Tablet
Prescription Required
Product introduction
Siropan 1mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.
Siropan 1mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
Common side effects of this medicine include edema, increased blood lipid level, high blood pressure, abdominal pain, diarrhea, headache, fever, urinary tract infection, anemia, nausea, joint pain, and thrombocytopenia. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, swelling, etc.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.
Uses of Siropan Tablet
- Prevention of kidney transplant rejection
Benefits of Siropan Tablet
In Prevention of kidney transplant rejection
Siropan 1mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Siropan Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Siropan
- Nausea
- Increased blood lipid level
- Low blood platelets
- Headache
- Abdominal pain
- Fever
- Anemia (low number of red blood cells)
- Urinary tract infection
- Diarrhea
- High blood pressure
- Joint pain
- Edema (swelling)
How to use Siropan Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siropan 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Siropan Tablet works
Siropan 1mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Siropan 1mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Siropan 1mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Siropan 1mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Siropan 1mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Siropan 1mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Siropan 1mg Tablet is recommended.
Liver
CAUTION
Siropan 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Siropan 1mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
Dose adjustment is not recommended in patients with mild to moderate liver disease.
What if you forget to take Siropan Tablet?
If you miss a dose of Siropan 1mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Siropan 1mg Tablet is used to prevent organ rejection following a kidney transplant operation.
- Avoid grapefruit juice while you are on treatment with this medicine. This is because a chemical in grapefruit juice increases the amount of Siropan 1mg Tablet in your bloodstream. This makes side-effects more likely.
- There is a possibility of a slight increase in the risk of skin cancer with Siropan 1mg Tablet. Do not use sunbeds, and avoid strong sunlight or use a sun cream with a high sun protection factor (SPF of at least 15).
- If you have diabetes mellitus, this medicine may affect your blood sugar levels. Monitor your sugar level regularly and report any extreme changes to your doctor.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- mTOR inhibitors
Interaction with drugs
Taking Siropan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Long-term concurrent use may increase the risk of certain brain infections.
Do not consume Natalizumab with Sirolimus.
Concomitant use may cause lethal infections.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Sirolimus or for up to 6
Enzalutamide may reduce blood levels of Sirolimus.
Do not consume Sirolimus with Enzalutamide. If concurrent use is essential, your doctor may monitor your treatment and adjust th
Concomitant use may cause lethal infections.
Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Sirolimus or for up to 6 months after stopping Siroli
Carbamazepine may reduce blood levels of Sirolimus.
Do not consume Sirolimus with Carbamazepine. If concurrent use is essential, your doctor may monitor your treatment and adjust
Patient concerns
User feedback
Patients taking Siropan 1mg Tablet
Once A Day
100%
What are you using Siropan Tablet for?
Others
50%
Prevention of*
50%
*Prevention of kidney transplant rejection
How much was the improvement?
Poor
50%
Excellent
50%
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1012-13.
- Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 972-73.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1267-68.
- Sirolimus. Sandwich, Kent: Pfizer Limited; 2001 [revised Oct. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
- Sirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc; 1999. [Accessed 06 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:
- Sirolimus [Product Description]. Ahmedabad, Gujarat: La Renon Heathcare Pvt. Ltd. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: Panacea Biotec Pharma Ltd
Address: "Panacea Biotec Pharma Ltd B-1,Extn/A-27,Mohan Co-operative Industrial Estate Mathura Road, New Delhi-110044"
Country of origin: India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Siropan 1mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Siropan 1mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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