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Qoxy 25 PR Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 19 Mar 2026 | 04:13 PM (IST)
Qoxy 25 PR Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is used to treat major depression and anxiety-related conditions like obsessive-compulsive disorder and panic disorder.
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General Information

The content is shown in English
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image
Qoxy 25 PR Tablet image

Product introduction

Qoxy 25 PR Tablet can be taken with or without food. The dose and how often you need to take the medicine will be decided by your doctor. They may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse, or you may suffer from unpleasant withdrawal symptoms such as anxiety, restlessness, palpitations, dizziness, and sleep disturbances.


To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.


Some common side effects of Qoxy 25 PR Tablet include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.


Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Inform your doctor about all the medicines you are taking to ensure safety.

Uses of Qoxy Tablet PR

Benefits of Qoxy Tablet PR

Treatment of Major Depression
Qoxy 25 PR Tablet helps improve symptoms of major depression by lifting mood, restoring interest in daily activities, and reducing feelings of sadness or hopelessness. It supports better emotional balance over time, which can enhance overall functioning and quality of life.
Treatment of Obsessive-compulsive disorder
In obsessive-compulsive disorder (OCD), Qoxy 25 PR Tablet helps reduce the intensity and frequency of persistent thoughts and the urge to perform repetitive actions. This makes it easier for individuals to manage daily tasks and experience relief from the distress caused by these symptoms.
Treatment of Panic disorder
Qoxy 25 PR Tablet helps people with panic disorder by reducing the number and severity of panic attacks. It also helps ease the constant worry about having another attack. This helps the individuals to feel more in control and comfortable in situations they may have previously avoided.

Side effects of Qoxy Tablet PR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Qoxy
  • Fatigue
  • Dryness in mouth
  • Loss of appetite
  • Increased sweating
  • Nervousness
  • Low sexual desire
  • Insomnia (difficulty in sleeping)
  • Confusion
  • Yawning
  • Nausea
  • Tremors
  • Constipation
  • Erectile dysfunction
  • Delayed ejaculation
  • Decreased libido
  • Dizziness

How to use Qoxy Tablet PR

Use it as advised by your doctor or check the label for directions before use. Qoxy 25 PR Tablet may be taken with or without food.

How Qoxy Tablet PR works

Qoxy 25 PR Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder and obsessive-compulsive disorder.

Quick tips

  • It can take 2-3 weeks for Qoxy 25 PR Tablet to start working.
  • Do not stop treatment suddenly, as this may cause upset stomach, flu-like withdrawal symptoms, and sleep disturbance.
  • If your doctor asks you to stop Qoxy 25 PR Tablet, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Qoxy 25 PR Tablet, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Qoxy 25 PR Tablet is very less.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Qoxy 25 PR Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Qoxy 25 PR Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Qoxy 25 PR Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Qoxy 25 PR Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Qoxy 25 PR Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Qoxy 25 PR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Qoxy with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Tapentadol (Nasal Route)

Avoid concurrent use unless your doctor considers it safe.
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Paroxetine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Life-threatening

Zolmitriptan (Nasal Route)

If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor and adjust the doses as per the observations.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Paroxetine. If Tranylcypromine is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Life-threatening

Selegiline (Oral Route)

Do not consume Selegiline with Paroxetine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Paroxetine. Please consult your doctor.

Frequently asked questions

You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.
No, do not stop taking Qoxy 25 PR Tablet abruptly, without consulting your doctor. This is a common problem with Qoxy 25 PR Tablet that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.
Yes, Qoxy 25 PR Tablet use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.
Qoxy 25 PR Tablet should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Qoxy 25 PR Tablet. If your doctor has prescribed Qoxy 25 PR Tablet for your child and you are worried about these side effects, discuss it with your doctor.
No, you should not take Qoxy 25 PR Tablet if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Qoxy 25 PR Tablet. But Qoxy 25 PR Tablet may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.
Yes, you need to be careful while taking this medicine if you are a diabetic. Qoxy 25 PR Tablet may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

Fact Box

Chemical Class

Phenylpiperidines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake Inhibitors (SSRIs)

References

  1. Stahl SM, editor. Paroxetine. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
  3. Paroxetine [EMC Label]. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2025. [Accessed 25 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  5. Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2023. [Accessed 12 Dec. 2025] (online) Available from:
  6. Paroxetine hydrochloride [Product Monograph]. East Windsor, NJ: Aurobindo Pharma Ltd.; 2025. [Accessed 11 Nov. 2025] (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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