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Psorid 50 Capsule

Ciclosporin (50mg)
Genuine
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Psorid 50 Capsule is used to prevent the body from rejecting a new organ after a liver, kidney, heart transplant, or bone marrow transplantation. It weakens the immune system so that your body does not attack the new organ. It is also used to treat nephrotic syndrome, severe rheumatoid arthritis, and psoriasis.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 14 Apr 2026 | 04:20 PM (IST)
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Psorid 50 Capsule image
Psorid 50 Capsule image
Psorid 50 Capsule image
Psorid 50 Capsule image
Psorid 50 Capsule image
Psorid 50 Capsule image
Psorid 50 Capsule image

Product introduction

The amount of Psorid 50 Capsule you take depends on your weight, medical condition, and what you are being treated for. Your doctor will plan the correct dose for you. Do not change the dose without talking to your doctor. It can be taken with or without food. It is better to take it in the same way and at the same time every day to get the maximum benefit. Keep taking it for as long as you have been told to, even if you feel well. Stopping treatment may increase the risk of your transplanted organ being rejected.


The most common side effects of this medicine include headache, unusual growth of facial or body hair, high blood pressure, diarrhea, gingival hyperplasia, and tremors. Because it lowers your immune system, you may also catch more infections than usual. Tell your doctor straight away if you develop an infection. For the same reason, you may be more at risk of developing some cancers, particularly of the skin. You should limit your exposure to sunlight.


Before taking this medicine, you should tell your doctor if you have liver or kidney problems, high blood pressure, gout (increased uric acid levels in the blood), or epilepsy. Also, tell your doctor about all other medicines you are taking, as they may affect the working of the medicine. This medicine should only be used in pregnancy if it is clearly needed. However, it is not recommended while breastfeeding. You will have frequent medical tests while taking this medicine to check your blood pressure, liver and kidney function, and mineral levels. The results of tests may lead to changes in your dose.

Benefits of Psorid Capsule

Treatment of Psoriasis
Psorid 50 Capsule can be used to treat severe psoriasis when other treatments have not worked or are not appropriate. Psoriasis happens when skin cells are replaced more quickly than usual. This medicine can improve your skin and reduce the symptoms of rash, redness, and pain. The improvement in the appearance of your skin can boost your confidence and improve your life. Psoriasis is a long-term condition. You should keep taking this medicine for as long as it is prescribed.
Treatment of Rheumatoid arthritis
Psorid 50 Capsule helps manage rheumatoid arthritis by suppressing overactive immune responses that drive joint inflammation and damage. Reducing immune-mediated inflammation helps relieve joint pain, swelling, and stiffness, and can slow the progression of joint damage in patients with active disease. When used as instructed, it can improve physical function and support better day-to-day comfort in people with rheumatoid arthritis.
Prevention of organ rejection in transplant patients
Psorid 50 Capsule belongs to a group of medicines known as immunosuppressive agents. It lowers your immune response and reduces the chance of your body attacking the transplanted organ. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine suppresses the immune system and helps your body accept the new organ as if it were your own.

Side effects of Psorid Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Psorid
  • Nausea
  • Vomiting
  • Increased hair growth
  • Renal dysfunction
  • Loss of appetite
  • Diarrhea
  • Tremors
  • High blood pressure
  • Headache
  • Gingival hypertrophy (gum enlargement)

How to use Psorid Capsule

Take this medicine in the dose and duration as advised by your doctor. Psorid 50 Capsule may be taken with or without food.

How Psorid Capsule works

Psorid 50 Capsule is an immunosuppressant. It works by suppressing your body’s immune response to help accept a newly transplanted organ (e.g., liver, kidney, or heart). In rheumatoid arthritis, this immunosuppressive effect reduces inflammation (swelling) of joints and limits joint damage. In psoriasis, it works by reducing the activity of certain immune cells that cause overproduction of skin cells, thus improving scaling and redness.

Quick tips

  • Psorid 50 Capsule may take 3 to 4 months for the medication to work. Keep taking it as prescribed.
  • Your doctor may get regular blood tests done to check the levels of blood cells in your blood. Inform your doctor if you experience unexplained bruising or bleeding, sore throat, mouth ulcers, fever, or general illness.
  • Your doctor may monitor your kidney function regularly. Drink 8 to 10 glasses of water per day to help with your kidney function.
  • Do not stop taking Psorid 50 Capsule without talking to your doctor first.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Psorid 50 Capsule.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Psorid 50 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Psorid 50 Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Psorid 50 Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Psorid 50 Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver

Liver

CAUTION
Psorid 50 Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of kidney function test is advised while you are taking this medicine.

Interaction with drugs

Taking Psorid with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Rosuvastatin (Oral Route)

Do not consume Rosuvastatin with Ciclosporin. Ciclosporin may raise blood levels of Rosuvastatin.
Life-threatening

Simvastatin (Oral Route)

Do not consume Simvastatin with Ciclosporin. If concurrent use is essential, watch out for symptoms such as decreased blood pressure, headache or swelling. Please consult your doctor. Ciclosporin may raise blood levels of Simvastatin.
Life-threatening

Pitavastatin (Oral Route)

Do not consume Pitavastatin with Ciclosporin. Ciclosporin may raise blood levels of Pitavastatin.
Life-threatening

Lovastatin (Oral Route)

Do not consume Lovastatin with Ciclosporin. If concurrent use is essential, watch for symptoms such as unexplained muscle pain, tenderness, or weakness and consult your doctor. Ciclosporin may raise blood levels of Lovastatin.
Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Ciclosporin or for up to 6 months after stopping Ciclosporin.

Frequently asked questions

Psorid 50 Capsule is used in combination with other medications, which are used to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants. This medicine also helps to treat the symptoms of rheumatoid arthritis (a disease affecting the joints with pain and swelling) in patients whose symptoms were not relieved by methotrexate alone. It is also used to treat psoriasis (a skin disease in which red, scaly patches form on some areas of the body) and atopic dermatitis (skin allergies).
Take Psorid 50 Capsule for as long as the doctor has advised. The duration of treatment depends on whether you are taking it after a transplant or for the treatment of other conditions. Usually, the treatment may last for 8 weeks if you are taking it for a severe rash.
Take Psorid 50 Capsule strictly as advised by your doctor. The doctor will decide and carefully adjust your dose according to your medical requirements. It is important to keep a constant amount of Psorid 50 Capsule in the body, and hence, the medicine should be taken at the same time each day. Not only is the time of day important, but also when Psorid 50 Capsule is taken concerning meals.
Yes, Psorid 50 Capsule may cause weight gain. However, the changes in weight are uncommon side effects of this medicine. Consult your doctor if these side effects worry you.
Yes, the use of Psorid 50 Capsule may cause abnormal hair growth (hypertrichosis) as a common side effect of Psorid 50 Capsule, though it does not affect everyone.
Yes, Psorid 50 Capsule may cause fatigue as a common side effect. However, fatigue could also be due to an underlying disease. Discuss with your doctor if this side effect worries you.
Yes, the doctor may suggest tests to check the levels of Psorid 50 Capsule in your blood, especially if you have had a transplant. You may also be advised to get your blood pressure checked before the start of your treatment and regularly during treatment. In addition, liver and kidney function tests, along with your blood lipids (fats), will be checked.
Psorid 50 Capsule is known to suppress the immune system. This, as a result, increases your risk of developing cancers, particularly of the skin and lymphoid system. You should limit your exposure to sunlight and UV light by wearing appropriate protective clothing. Sunscreen should be applied frequently with a high protection factor.

Fact Box

Chemical Class

Cyclosporins

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Calcineurin Inhibitors

References

  1. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1821.
  2. Wallace JL, Sharkey KA. Pharmacotherapy of Inflammatory Bowel Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1358-59.
  3. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 630-31.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 340-42.
  5. Ciclosporine [EMC SmPC]. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2015. [Accessed 25 Jan. 2019] (online) Available from:
  6. Cyclosporine [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2015. [Accessed 06 Apr. 2019] (online) Available from:
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
  8. Cyclosporine [Prescribing Information]. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2024. [Accessed 17 Jan. 2026] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Eris Lifesciences Ltd
Address: 8th Floor, Commerce House IV, Prahladnagar, Ahmedabad – 380015 Gujarat, India \ 7th Floor, Commerce House-4, Prahlad Nagar, Ahmedabad, Gujarat - 380015

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Psorid 50 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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