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Pitavastatin is used along with diet regimens to lower excessive fats (cholesterol and triglycerides, apolipoprotein B) and increase the levels of good cholesterol (high-density lipoproteins-HDL) in patients with hereditary disorder of excess fats in blood (primary or mixed hyperlipidemia).

How it works

Pitavastatin belongs to a class of medicines called HMG CoA reductase inhibitor (statins). It inhibits an enzyme called HMG-CoA reductase that is required for the production of cholesterol in the body and thereby reduces the amount of bad cholesterol (low-density lipoproteins-LDL) and increases the levels of good cholesterol (high-density lipoproteins-HDL) in the blood. 

Common side effects

Pain in extremity, Liver enzyme increased, Back pain, Breakdown of damaged muscle tissue, Constipation, Diarrhoea, Muscle disorder, Muscle pain


Expert advice

  • Maintain dietary restrictions while on treatment.
  • Stop taking pitavastatin and contact your doctor immediately, if you experience unexplained pain, weakness and tenderness in muscles,  accompanied with fever and a feeling of discomfort (malaise), fits (uncontrolled seizures), elevated levels of creatine kinase, very low blood pressure (hypotension) or any other medical emergency.
  • Tell your doctor if you have diabetes, an underactive thyroid gland (hypothyroidism), renal or liver diseases or muscle disorders, before starting pitavastatin treatment.
  • You should be regularly monitored for liver function test to check rise in liver enzyme levels (transaminases) and blood glucose and Hb1Ac levels are recommended.
  • Take extreme care to avoid pregnancy if you are taking pitavastatin or any other statins and consult your doctor immediately if you get to know that you are pregnant.

Frequently asked questions


Q. Pitavastatin is superior to atorvastatin?
Pitavastatin and atorvastatin are different drugs belonging to the same class of HMG CoA reductase inhibitor (statins) and have the same mechanism of action. Their use in different conditions may vary depending upon individual response and therefore comparison between the two drugs cannot be drawn. Please follow your doctor’s advice regarding their use.

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)