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12 Aug 2022 | 12:45 AM (IST)

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Promez Syrup

Prescription Required
Store below 30°C

Your child’s medicine at a glance

Promez Syrup treats allergic and short-term common cold symptoms like runny nose, sneezing, watery eyes, skin rash, and itching in children. It also helps treat nausea, and vomiting caused after surgery or due to motion sickness (travel sickness).

When given post-surgery, it makes your child sleepy and relaxed, helping the pain-relieving medicines work better. Give Promez Syrup to your child by mouth either before or after food. If your child develops stomach upset, give it preferably after food. The usual prescribed frequency is two to four times a day but may vary as per your child’s condition. For motion sickness, give Promez Syrup 30 to 60 minutes before travel whereas to prevent vomiting post-surgery, you may need to give it a night before the surgical procedure or just before the surgery and may need to continue it afterward as directed.

If your child vomits within 30 minutes of taking this medicine, give the same dose again. However, never repeat the dose if the next scheduled dose is near. Your child may start to feel better within a few days of regular dosing. However, you must continue giving the medicine to your child to finish the complete prescribed course as stopping it abruptly may worsen your child’s condition.

Some of the minor and temporary side effects that your child may experience while taking Promez Syrup include dry mouth, blurring of vision, drowsiness, dizziness, and constipation. These side effects usually subside once your child’s body adapts to the medicine. In case they persist or become bothersome for your child, consult your child’s doctor without any delay.

Inform the doctor if your child has any ongoing medicine regime or history of any allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, skin disorder, liver impairment, and kidney malfunction. Awareness of your child’s medical history will help the doctor make dose alterations and better treatment planning.

Benefits of Promez Syrup for your child

In Treatment of Nausea

Promez Syrup blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment. This medicine helps you recover more comfortably. The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

In Treatment of Allergic conditions

Promez Syrup is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.

This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.

In Treatment of Motion sickness

Motion sickness is a condition caused due to motion during travel. You may experience spinning sensation (vertigo), nausea or vomiting as a result of this condition. Promez Syrup helps treat these symptoms effectively. Take it as prescribed by the doctor to get maximum benefit.

Side effects of Promez Syrup in children

Promez Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Promez

  • Constipation
  • Slow heart rate
  • Hypotension (low blood pressure)
  • Tremors

Serve side effects of Promez

  • Unusual production of breast milk in women and men

How can I give Promez Syrup to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Promez Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Promez Syrup works

Promez Syrup is an antiallergic medication. When the body is exposed to an allergen (pollen, animal dander, house dust, etc.), it releases a chemical called histamine. This chemical causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching, etc. Promez Syrup also works directly on several areas of the brain to prevent nausea and vomiting and help you feel more relaxed.

Safety advice

Promez Syrup is safe to use in patients with kidney disease. No dose adjustment of Promez Syrup is recommended.
Discuss with your child’s doctor thoroughly before giving Promez Syrup to your child in case of severe kidney disease
Promez Syrup should be used with caution in patients with liver disease. Dose adjustment of Promez Syrup may be needed. Please consult your doctor.
Use of Promez Syrup is not recommended in children with severe liver disease and active liver disease.

What if I forget to give Promez Syrup to my child?

Do not panic. The missed dose can be given as soon as you remember, but only if your child’s doctor advises to. Do not give the missed dose if it is almost the time for the next dose. Follow the prescribed dosing schedule and do not give a double dose to catch up with the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips

  • Stop taking it at least three days before taking an allergy test as it can affect the test results.
  • Promez Syrup may make your child feel sleepy. Ensure your child takes extra care when taking part in physical activities.
  • Avoid using Promez Syrup in children less than 2 years of age as it can cause fatal respiratory distress.
  • Do not give Promez Syrup if your child has liver disease. Tell the complete medical history of your child to the doctor.
  • Stop Promez Syrup and immediately report to the doctor if your child develops an itchy rash, facial swelling, or breathing difficulties.

Fact Box

Chemical Class
Phenothiazine Derivative
Habit Forming
Therapeutic Class
Action Class
H1 Antihistaminics (First Generation)

Interaction with drugs

Taking Promez with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rasalect, Relgin, Rasipar
Brand(s): Selgelin, Jumex, Selgin
Brand(s): Zuvair
Brand(s): Eurolam

Patient concerns

Medicine for Nausea, vomiting, morning sickness for pregnant lady(3months)
Dr. Megha Tuli
Obstetrics and Gynaecology
Doxinate. Thrice a day
I feel uneasy during traveling in car i feel vomiting tendency
Dr. Jyoti Kapoor Madan
You may have motion sickness. Please see an ENT specialist.

User feedback


Q. My child is 1 year old. Is it safe to give Promez Syrup to my child who is suffering from a common cold?

Promez Syrup should not be given to children less than 2 years of age as it may cause fatal respiratory depression wherein your child’s breathing may stop completely.

Q. What if I give an overdose of Promez Syrup by mistake?

Always stick to the prescribed dose. Prolonged or excess intake of Promez Syrup can put your child at risk of developing serious side effects like bradycardia, decreased blood pressure, confusion, delirium, disorientation, dizziness, drowsiness, and hallucinations. Rush to your child’s doctor immediately if you feel you have given excess Promez Syrup to your child. To pour out the right dose, use the calibrated cup provided with the medicine by the manufacturer. Do not use a kitchen teaspoon as it will not give the correct estimate.

Q. When will my child’s condition improve after taking Promez Syrup?

Promez Syrup usually starts working within 30 to 60 minutes of intake and shows its peak effect within 3 to 4 hours. Your child may start to feel better after a few doses. In case the symptoms persist longer, consult your child’s doctor immediately.

Q. Can other medicines be given at the same time as Promez Syrup?

Promez Syrup can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Promez Syrup. Also, check with your child’s doctor before giving any medicine to your child.

Q. Can Promez Syrup make my child sleepy?

Promez Syrup may cause mild drowsiness, making your child feel sleepy. So, be cautious and never give this medicine if your child is suffering from a sleep disorder as this medicine can mask the symptoms of underlying sleep disorders like insomnia. It is always best to consult your child’s doctor before giving this medicine to your child.

Q. Where should I keep Promez Syrup?

Keep Promez Syrup out of the reach and sight of children to avoid any accidental intake. Keep it at room temperature, in a dry place, away from direct heat and light.

Q. When should I call my child’s doctor right away?

You should call the doctor without any delay if your child starts to develop side effects such as irregular heartbeat, vision problem, muscle spasm, irregular bodily movements, sudden weakness, and inability to empty the bladder completely (urinary retention).

Q. My child is an athlete and has to participate in a sports event in the school. Can I give Promez Syrup before his performance?

This medicine may cause CNS depression in which the normal nerve functioning slows down. So, avoid giving Promez Syrup to your child if he/she is scheduled to perform tasks that require mental alertness.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Promethazine HCl. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2004. [Accessed 20 Jan. 2021] (online) Available from:External Link
  2. Medline Plus. Promethazine. [Last revised 15 Jun. 2017]. [Accessed 20 Jan. 2021] (online) Available from:External Link
  3. Nationwide Children’s. Promethazine oral solution or syrup. [Accessed 20 Jan. 2021] (online) Available from:External Link

Manufacturer/Marketer address

plot number 48, first floor, phase - i, industrial area phase i, chandigarh, 160002
Country of origin: India
We do not facilitate sale of this product at present


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