Product introduction
Praxet-CR 37.5 Tablet PR is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is widely prescribed to treat depression and anxiety-related conditions like obsessive-compulsive disorder, and panic disorder.
Praxet-CR 37.5 Tablet PR helps many people to recover from depression by improving their mood and relieving anxiety and tension. It can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms.
Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).
To get the most benefit, take this medicine regularly at the same time each day. Your doctor may advise you to take it in the morning if you have trouble sleeping. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.
Some common side effects of Praxet-CR 37.5 Tablet PR include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, insomnia (difficulty in sleeping), and constipation. Sexual side effects like decreased sexual drive, delayed ejaculation, and erectile dysfunction may also be seen. Let your doctor know straight away if you develop any sudden worsening of mood or any thoughts about harming yourself.
Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.
Uses of Praxet Tablet PR
- Depression
- Anxiety disorder
- Obsessive-compulsive disorder
- Phobia
- Post traumatic stress disorder
- Treatment of Panic disorder
Benefits of Praxet Tablet PR
In Treatment of Panic disorder
Praxet-CR 37.5 Tablet PR can help relieve symptoms of many panic disorders including panic attacks. It can help you feel calmer and improve your ability to deal with problems. Do not stop taking it, even when you feel better, unless your doctor advises you to.
Side effects of Praxet Tablet PR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Praxet
- Fatigue
- Dryness in mouth
- Loss of appetite
- Increased sweating
- Nervousness
- Nausea
- Tremors
- Low sexual desire
- Insomnia (difficulty in sleeping)
- Confusion
- Constipation
- Erectile dysfunction
- Delayed ejaculation
- Decreased libido
- Dizziness
- Yawning
How to use Praxet Tablet PR
Use it as advised by your doctor or check the label for directions before use. Praxet-CR 37.5 Tablet PR may be taken with or without food, but it is better to take it at a fixed time.
How Praxet Tablet PR works
Praxet-CR 37.5 Tablet PR is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic disorder, anxiety, and obsessive-compulsive disorder.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Praxet-CR 37.5 Tablet PR.
Pregnancy
UNSAFE
Praxet-CR 37.5 Tablet PR is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Praxet-CR 37.5 Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Praxet-CR 37.5 Tablet PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Praxet-CR 37.5 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Praxet-CR 37.5 Tablet PR may be needed. Please consult your doctor.
Liver
CAUTION
Praxet-CR 37.5 Tablet PR should be used with caution in patients with liver disease. Dose adjustment of Praxet-CR 37.5 Tablet PR may be needed. Please consult your doctor.
What if you forget to take Praxet Tablet PR?
If you miss a dose of Praxet-CR 37.5 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Praxet-CR 37.5 Tablet PR
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Quick tips
- It can take 2-3 weeks for Praxet-CR 37.5 Tablet PR to start working.
- Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
- If your doctor asks you to stop Praxet-CR 37.5 Tablet PR, you should reduce the dose slowly over 4 weeks.
- Avoid consuming alcohol when taking Praxet-CR 37.5 Tablet PR, as it may cause excessive drowsiness and calmness.
- The addiction/dependence potential of Praxet-CR 37.5 Tablet PR is very less.
Fact Box
Chemical Class
Phenylpiperidine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Selective Seretonin Reuptake Inhibitors (SSRIs)
Interaction with drugs
Taking Praxet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Selegiline with Paroxetine. If Selegiline is essential, ensure a gap of at least 2 weeks after discontinuing Paroxetine. Please consult your doctor.
Concomitant use
If concurrent use is essential, watch out for symptoms of serotonin syndrome such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doct
Do not consume Moclobemide with Paroxetine. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Concomitant us
Avoid concurrent use unless your doctor considers it safe.
Concurrent use may cause fatal rise in blood serotonin levels.
Do not consume Tranylcypromine with Paroxetine. If Tranylcypromine is essential, ensure a gap of at least 1 week after discontinuing Paroxetine. Please consult your doctor.
Concom
Patient concerns
FAQs
After how many days of taking Praxet-CR 37.5 Tablet PR will I start feeling better?
You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.
I feel that my symptoms have worsened after having started taking Praxet-CR 37.5 Tablet PR. Can I stop it on my own or do I need to consult the doctor?
No, do not stop taking Praxet-CR 37.5 Tablet PR abruptly, without consulting your doctor. This is a common problem with Praxet-CR 37.5 Tablet PR that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.
Can Praxet-CR 37.5 Tablet PR affect my sex life?
Yes, Praxet-CR 37.5 Tablet PR use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.
What is the effect of Praxet-CR 37.5 Tablet PR on children?
Praxet-CR 37.5 Tablet PR should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Praxet-CR 37.5 Tablet PR. If your doctor has prescribed Praxet-CR 37.5 Tablet PR for your child and you are worried about these side effects, discuss it with your doctor.
I have been taking tamoxifen for breast cancer. Can I take Praxet-CR 37.5 Tablet PR with it?
No, you should not take Praxet-CR 37.5 Tablet PR if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Praxet-CR 37.5 Tablet PR. But Praxet-CR 37.5 Tablet PR may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.
Do I need to be careful while taking Praxet-CR 37.5 Tablet PR if I am a diabetic?
Yes, you need to be careful while taking this medicine if you are a diabetic. Praxet-CR 37.5 Tablet PR may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Stahl SM, editor. Paroxetine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 513-19.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1060-69.
- Paroxetine.Miami, Florida:Noven Therapeutics; 2003 [revised 06-2013]. [Accessed 25 Mar 2019] (online) Available from:
- Chaves RG, Lamounier GA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 25 Mar. 2019] (online) Available from:
- Paroxetine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 25 Nov. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paroxetine. [Updated 2019 Oct 23]. [Accessed 20 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Paroxetine [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2022. [Accessed 03 Aug. 2023] (online) Available from:
- Paroxetine. Prescribing Information. Dailymed; 2025. [Acessed 10 Sep. 2025] (online) Available from:
Marketer details
Name: Solvate Laboratries Pvt Ltd
Address: Solvate Laboratories Pvt.Ltd., C-57, IIIrd Floor, Vikas Marg, Preet Vihar, Delhi-110092
Country of origin: India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Praxet-CR 37.5 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Praxet-CR 37.5 Tablet PR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹363.8 4% OFF
₹350
Inclusive of all taxes
10.0 Tablet pr in 1 strip
New GST benefit included in this MRP, may differ from label
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