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Polymxe 1Million IU Injection

Colistin Sulphate (1Million IU)
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Polymxe 1Million IU Injection is an antibiotic that fights bacteria. It is used to treat severe infections of the lungs, stomach, urinary tract, blood, and others. It works by killing the bacteria that cause these problems. It is commonly used to treat critically ill patients admitted to the hospital.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Apr 2026 | 01:19 PM (IST)
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Gurgaon
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Polymxe 1Million IU Injection image
Polymxe 1Million IU Injection image

Product introduction

Polymxe 1Million IU Injection is given under the supervision of a healthcare professional. You should not self-administer this medicine at home. The dose and duration will be decided by your doctor based on the severity and type of infection you have. Get the injection regularly for as long as your doctor has prescribed to get maximum benefits.

It may cause pain, swelling, or redness at the site of injection. However, these are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. It can even cause kidney damage in some people. You might need to be monitored while on this medication. 

Before starting treatment with this medicine, you should tell the doctor if you are allergic to any antibiotic or have any liver or kidney problems. Pregnant or breastfeeding mothers should consult their doctor before using it. Your doctor may get regular blood tests done to monitor kidney function and the level of the medicine in your blood.

Uses of Polymxe Injection

  • Treatment of Severe bacterial infections

Benefits of Polymxe Injection

Treatment of Severe bacterial infections
Polymxe 1Million IU Injection is an antibiotic that is used to treat certain bacterial infections such as stomach and intestinal infections. It works by killing bacteria causing infections. Take it in the exact dose and duration as prescribed by your doctor. This medicine usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Polymxe Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Polymxe
  • Diarrhea
  • Kidney damage
  • Nausea
  • Vomiting

How to use Polymxe Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Polymxe Injection works

Polymxe 1Million IU Injection is an antibiotic. It kills bacteria by destroying the bacterial cell membrane.

All substitutes for Polymxe 1Million IU Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • It is given by a drip or by injection into the vein under the supervision of a doctor.
  • It may also be used to kill the natural bacteria that are present in the stomach before surgery on the stomach.
  • Do not use it for any other types of bacterial infections.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Polymxe 1Million IU Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Polymxe 1Million IU Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Polymxe 1Million IU Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Polymxe 1Million IU Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Polymxe 1Million IU Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Polymxe 1Million IU Injection in patients with liver disease.

Interaction with drugs

Taking Polymxe with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Capreomycin (Injection Route)

If concurrent use is essential, your doctor may monitor your blood pressure frequently.
Severe

Vancomycin (Injection Route)

If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Severe

Amikacin (Injection Route)

Do not consume Colistin Sulphate with Amikacin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Severe

Gentamicin (Injection Route)

Do not consume Colistin Sulphate with Gentamicin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Severe

Kanamycin (Injection Route)

Do not consume Colistin Sulphate with Kanamycin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Before taking Polymxe 1Million IU Injection, you must tell your doctor if you have or ever had any problems related to your kidneys or liver. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
Use of Polymxe 1Million IU Injection should be avoided in patients who are allergic to Polymxe 1Million IU Injection or any of its components. However, if you are not aware of any allergy or if you are using Polymxe 1Million IU Injection for the first time, consult your doctor.
Enough evidence is not available to provide clarity on the use of Polymxe 1Million IU Injection in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Polymxe 1Million IU Injection. You may take it only if prescribed by your doctor.
Polymxe 1Million IU Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Polymxe 1Million IU Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Polymxe 1Million IU Injection too early, the symptoms may return or worsen.
If you forget a dose of Polymxe 1Million IU Injection, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Cell membrane active agent

Related lab tests

100% genuine products
100% genuine products
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Polymxe 1Million IU Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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