




Plepon 6 Tablet ER
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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General Information






Product introduction
Plepon 6 Tablet ER may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness.
Some common side effects of this medicine include drowsiness, anxiety, increased heart rate and tremor. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.
You should be cautious if you are using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.
Uses of Plepon Tablet ER
Benefits of Plepon Tablet ER
Mania means extremely excited or elevated mood. Plepon 6 Tablet ER helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Plepon 6 Tablet ER will ensure that you have a better social life and are able to do daily activities more comfortably.
Side effects of Plepon Tablet ER
- Abnormal involuntary movements
- Dizziness
- Injection site reactions (pain, swelling, redness)
- Nystagmus (involuntary eye movement)
- Sleepiness
- Tremors
- Cogwheel rigidity
- Nasopharyngitis (inflammation of the throat and nasal passages)
How to use Plepon Tablet ER
How Plepon Tablet ER works
All substitutes for Plepon 6 Tablet ER
Quick tips
- Take it in the morning, preferably at the same time every day.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Use caution while driving or doing anything that requires concentration as Plepon 6 Tablet ER can cause dizziness and sleepiness.
- It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly.
- Monitor your blood sugar regularly as Plepon 6 Tablet ER can affect blood sugar levels.
- Do not stop taking Plepon 6 Tablet ER without talking to your doctor first as it may cause a worsening of symptoms.Â
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney
Use of Plepon 6 Tablet ER is not recommended in patients with end-stage kidney disease.

Liver
Limited information is available on the use of Plepon 6 Tablet ER in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
Interaction with drugs
Escitalopram Oxalate (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Stahl SM, editor. Paliperidone. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 503-508.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1047-48.
- Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2007 [revised 13 Sep. 2018]. [Accessed 23 Jan. 2019] (online) Available from:
- Paliperidone. Vacaville, California: ALZA Corporation; 2006. [Accessed 25 Mar 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paliperidone. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
- Paliperidone. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 13 Sep. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
- Paliperidone. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2025. [Accessed 11 Jul. 2025] (online) Available from:




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Disclaimer
Marketer details
Address: Shop No. 6 to 10, 1st Floor, Balaji Heights, Sector-11, Sanpada, Navi Mumbai-400 705
Vendor Details
A licensed vendor partner from your nearest location will deliver Plepon 6 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)















