Piolet 15mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Piolet 15mg Tablet is a medicine used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. This helps to prevent serious complications of diabetes like kidney damage and blindness.

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Pioglit 15 Tablet

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Piolet 15mg Tablet

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Same composition

Pioglit 15 Tablet

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Pioglitazone (15mg)

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General Information

Contains

Pioglitazone (15mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Piolet 15mg Tablet may be used by itself or along with other medicines. It may be taken with or without food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking this medicine include headache, sinusitis, muscle pain, and pharyngitis. Consult your doctor if any of these side effects bother you or persist for a longer duration.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Piolet Tablet

Type 2 diabetes mellitus

Benefits of Piolet Tablet

Type 2 diabetes mellitus
Piolet 15mg Tablet is used to help manage type 2 diabetes by improving the body’s response to insulin. It supports better blood sugar control, which can reduce the risk of diabetes-related complications and improve overall health.

Side effects of Piolet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Piolet

Sore throat
Sinus inflammation
Muscle pain
Headache

How to use Piolet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Piolet 15mg Tablet may be taken with or without food.

How Piolet Tablet works

Piolet 15mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

All substitutes for Piolet 15mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Piolet 15mg Tablet helps to control blood sugar level and avoid long-term complications.
Take it only as per dose and duration suggested by your doctor.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Piolet 15mg Tablet.
Full effects may be visible after several weeks of starting Piolet 15mg Tablet. Keep taking it as prescribed by your doctor.
Monitor your blood sugar level regularly while taking this medicine.
Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes and loss of appetite.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Piolet 15mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Piolet 15mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Piolet 15mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Piolet 15mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Piolet 15mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

SAFE IF PRESCRIBED

Piolet 15mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Piolet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.

Moderate

Mifepristone (Oral Route)

Watch out for symptoms of Pioglitazone side effects such as headache, nausea, dizziness or weakness and consult your doctor if you experience them. Mifepristone may raise blood levels of Pioglitazone.

Moderate

Asparaginase (Injection Route)

Your doctor may monitor your diabetic control closely and adjust the doses as per the observations.

Moderate

Aceclofenac (Oral Route)

Do not use Pioglitazone with Aceclofenac. If concurrent use is essential, let your doctor know if you develop symptoms of fluid retention, such as shortness of breath or ankle swelling.

Moderate

Aceclofenac (Injection Route)

Do not use Pioglitazone with Aceclofenac. If concurrent use is essential, let your doctor know if you develop symptoms of fluid retention, such as shortness of breath or ankle swelling.

Frequently asked questions

Can Piolet 15mg Tablet cause weight gain?

Piolet 15mg Tablet commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.

Can Piolet 15mg Tablet cause heart failure?

Piolet 15mg Tablet can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Piolet 15mg Tablet is used with insulin.

Can you take Piolet 15mg Tablet and metformin together?

Yes, Piolet 15mg Tablet can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.

What time of day should you take Piolet 15mg Tablet?

It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Piolet 15mg Tablet exactly as prescribed by your doctor.

How long do I need to take Piolet 15mg Tablet? Can I stop the medicine for some time?

Continue taking Piolet 15mg Tablet as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.

Does Piolet 15mg Tablet affect liver?

Yes, Piolet 15mg Tablet may cause an increase in liver enzymes, and treatment with Piolet 15mg Tablet should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Piolet 15mg Tablet should not be prescribed to patients with liver disease.

What kind of medicine is Piolet 15mg Tablet? Is it like metformin?

Piolet 15mg Tablet belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Can Piolet 15mg Tablet cause bladder cancer?

Piolet 15mg Tablet may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Piolet 15mg Tablet should not be used in patients with a prior history of bladder cancer or having bladder cancer.

Fact Box

Chemical Class

Phenol ethers

Habit Forming

Therapeutic Class

ANTI DIABETIC

Action Class

Thiazolidinediones (TZD) and PPAR Gamma Agonists

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1259-61.
Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 742-43.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1124-25.
Pioglitazone. Deerfield, Illinois; Takeda Pharmaceuticals America, Inc.; 1999 [revised Nov. 2013]. [Accessed 28 Jan. 2019] (online) Available from:
Pioglitazone hydrochloride [Product monograph]. Ontario, Canada: Takeda Canada Inc.; 2018. [Accessed 8 Oct. 2021] (online) Available from:
Actos [Summary of Product Characteristics]. County Wicklow, Ireland: Takeda Ireland Limited; 2010. [Accessed 8 October. 2021] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:
Pioglitazone hydrochloride [Prescribing Information]. Baddi, Himachal Pradesh, India: Macleods Pharmaceutical Ltd.; 2022. [Accessed 05 Aug. 2023] (online) Available from:

User feedback

Patients taking Piolet 15mg Tablet

Once A Day

89%

Twice A Day

11%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Piolet 15mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Piolet Tablet

Benefits of Piolet Tablet

Side effects of Piolet Tablet

How to use Piolet Tablet

How Piolet Tablet works

All substitutes for Piolet 15mg Tablet

Pioz 15 Tablet

Pioglit 15 Tablet

Piosys 15 Tablet

Pioglar 15 Tablet

piONORM 15 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Mifepristone (Oral Route)

Asparaginase (Injection Route)

Aceclofenac (Oral Route)

Aceclofenac (Injection Route)

Frequently asked questions

Can Piolet 15mg Tablet cause weight gain?

Can Piolet 15mg Tablet cause heart failure?

Can you take Piolet 15mg Tablet and metformin together?

What time of day should you take Piolet 15mg Tablet?

How long do I need to take Piolet 15mg Tablet? Can I stop the medicine for some time?

Does Piolet 15mg Tablet affect liver?

What kind of medicine is Piolet 15mg Tablet? Is it like metformin?

Can Piolet 15mg Tablet cause bladder cancer?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

User feedback

Patients taking Piolet 15mg Tablet

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests