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02 Nov 2019 | 01:14 PM (IST)
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PHOSOME 25 MG INJECTION

Prescription Required

Overview

Introduction of Phosome Injection

PHOSOME 25 MG INJECTION is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills fungi by destroying the fungal cell membrane.

PHOSOME 25 MG INJECTION is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood

It may lead to a few common side effects like headache, nausea and vomiting. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Phosome Injection

Phosome Injection side effects

Common
  • Headache
  • Vomiting
  • Nausea
  • Stomach cramp
  • Fever
  • Anemia (low number of red blood cells)
  • Heartburn
  • Rapid breathing

How to use Phosome Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Phosome Injection works

PHOSOME 25 MG INJECTION is an antifungal medication. It kills fungi by destroying the fungal cell membrane.

Phosome Injection related warnings

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with PHOSOME 25 MG INJECTION. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
PHOSOME 25 MG INJECTION is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Lactation
CONSULT YOUR DOCTOR
PHOSOME 25 MG INJECTION is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
PHOSOME 25 MG INJECTION may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
PHOSOME 25 MG INJECTION is safe to use in patients with kidney disease. No dose adjustment of PHOSOME 25 MG INJECTION is recommended.
However, inform your doctor if you have any underlying kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of PHOSOME 25 MG INJECTION in patients with liver disease. Please consult your doctor.

What if you miss a dose of Phosome Injection?

If you miss a dose of PHOSOME 25 MG INJECTION, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
PHOSOME 25 MG INJECTION
Fungisome 25mg Injection
Lifecare Innovations Pvt Ltd
₹119.12/ml of Injection
save 36%
Lambin 25mg INJECTION
Sun Pharmaceutical Industries Ltd
₹2909.48/Injection
1473% costlier
Amphotin Lip 25mg Injection
United Biotech Pvt Ltd
₹399/ml of Injection
116% costlier

Expert Advice

  • It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
  • PHOSOME 25 MG INJECTION can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
  • Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
  • Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Interaction with Drugs

Taking Phosome with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Begenta, Indogenta
SERIOUS
Brand(s): Zencort-M
SERIOUS
Brand(s): Indizole, Itraspan, Canzit
SERIOUS
Brand(s): Ranisol
SERIOUS
Brand(s): Bactob
SERIOUS
Brand(s): Ketozoe, Ketazol
SERIOUS
Brand(s): Ducort, Defmark
SERIOUS
Brand(s): Mikasun, Vizocin, Amricin
SERIOUS
Brand(s): Budojet
SERIOUS
Brand(s): Fungis
SERIOUS

Patient Concerns

Questions Related to Phosome

arrow
I have fungal infections on my legs, it itchsI am using fluka 150 mg but not getting positive resultsWith Tenovat M skin cream
Dr. Preeti Chhabra
Skin Specialist
Apply Fungase ointment, Nimba Tail and Karanj tail
I have been experiencing fungal infections, I develop rings and rashes and they all itch like anything. I formed scars because of it. I have been taking Grisovin FP 250 mg however as long I take it I am relieved, even if I miss it for 1 day I start getting fungus back. On top of that Grisovin FP is difficult to find now, please suggest.
Dr. Atul Jain
Skin Specialist
You are having fungal infections severe, you need to change the medicine by skin specialistCan b prescribed under supervisionMeanwhile apply onabet cream twice a day
arrow
Do you have any questions related to PHOSOME 25 MG INJECTION?

FAQs

Q. Is Phosome fungistatic or fungicidal?

Phosome is fungicidal in nature, it acts by killing the fungus

Q. Is Phosome light sensitive?

Phosome is not light sensitive

Q. What is Phosome liposomal?

Liposomal Phosome is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Phosome can substantially improves drug safety especially nephrotoxicity associated with the drug

Q. Is Phosome an antibiotic?

Yes, Phosome is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)

Q. Is Phosome testing dose needed?

Yes, administration of Phosome is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity

Q. How is Phosome administered?

Phosome is either administered as intravenous injection or infusion by a registered medical professional only

Q. How does Phosome cause nephrotoxicity and hyperkalemia?

Phosome can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
  2. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
  3. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 68-69.
  5. Medsacpe. Amphotericin. [Accessed 29 Mar. 2019] (online) Available from:External Link
  6. Amphotericin B. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 04 Feb. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5):4-6. [Accessed 29 Mar. 2019] (online) Available from:External Link
  8. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
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We do not facilitate sale of this product at present

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