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Pfend 200mg Tablet

Pirfenidone (200mg)

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Pfend 200mg Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis. It reduces scarring and swelling in the lungs and helps to breathe better.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 21 Jan 2026 | 01:53 AM (IST)

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General Information

Contains

Pirfenidone (200mg)

Marketer

Remalthea Pharmaceuticals Private Limited

Storage

Store below 30°C

The content is shown in English

Product introduction

Pfend 200mg Tablet is best taken with food. Take it at the same time every day to get the most benefits. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include insomnia, headache, dizziness, dyspepsia, nausea, diarrhea, and photosensitivity. To overcome dizziness, avoid driving or engaging in attention-seeking activities. Some people may experience weight loss and other side effects. Monitor your weight regularly or ask for the doctor's advice in such cases. Your doctor also may perform a liver function test while on treatment with this medicine.

Before taking this medicine, let your doctor know if you have liver or kidney disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. It makes your skin sun-sensitive, so wear protective clothing or apply sunscreen while in direct contact with the sun. Inform your doctor if you are pregnant or breastfeeding.

Uses of Pfend Tablet

Treatment of Idiopathic pulmonary fibrosis

Benefits of Pfend Tablet

Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible, and the affected person may experience shortness of breath or a dry cough as initial symptoms. Pfend 200mg Tablet reduces the scarring or fibrosis and makes breathing easier.

Side effects of Pfend Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pfend

Headache
Dizziness
Insomnia (difficulty in sleeping)
Sinus inflammation
Tiredness
Photosensitivity
Loss of appetite
Weight loss
Upper respiratory tract infection

How to use Pfend Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pfend 200mg Tablet should be taken with or after food.

How Pfend Tablet works

Pfend 200mg Tablet is an antifibrotic medication. It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis. This reduces the scarring and swelling in the lungs and makes breathing easier.

All substitutes for Pfend 200mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Pfend 200mg Tablet reduces scarring and swelling in the lungs, and helps you breathe better.
It is best to take this medicine with food and at the same time each day.
This medication may make you more sensitive to the sun. Use sunscreen and wear protective clothing when outdoors.
Stop smoking during treatment with Pfend 200mg Tablet as it can reduce the effect of the treatment.
Stop smoking during treatment with Pfend 200mg Tablet, as it can reduce the effect of the treatment.
It may cause weight loss. Monitor your weight regularly.
Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pfend 200mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Pfend 200mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Pfend 200mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Pfend 200mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pfend 200mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pfend 200mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pfend with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Fluvoxamine (Oral Route)

Do not consume Pirfenidone with Fluvoxamine. Fluvoxamine may raise blood levels of Pirfenidone.

Moderate

Axitinib (Oral Route)

Watch out for symptoms of Pirfenidone side effects such as diarrhea, itching or skin rash, nausea, redness of the skin, stomach discomfort or vomiting and consult your doctor if you experience them. They may adjust the doses as per the observations. Axitinib may raise blood levels of Pirfenidone.

Moderate

Allylestrenol (Oral Route)

Watch out for symptoms of Pirfenidone side effects such as diarrhea, itching or skin rash, nausea, redness of the skin, stomach discomfort or vomiting and consult your doctor if you experience them. Allylestrenol may raise blood levels of Pirfenidone.

Moderate

Amiodarone (Oral Route)

Moderate

Amiodarone (Injection Route)

Frequently asked questions

What monitoring will I need during treatment with Pfend 200mg Tablet?

Your doctor will check your liver function before starting treatment with Pfend 200mg Tablet. This test will be repeated monthly for the first 6 months, and then it will be done every three months. In addition to that, your doctor will also monitor your lung function periodically in order to see the response to Pfend 200mg Tablet.

Why is it important to continue treatment with Pfend 200mg Tablet?

It is important to control the progression of the disease by preserving your lung function, which cannot be restored once lost. Hence, it is highly recommended to start and continue the treatment with Pfend 200mg Tablet as prescribed by your doctor. Doing so can help preserve the existing lung function.

How do I know that Pfend 200mg Tablet is right for me?

Only you and your doctor can decide if Pfend 200mg Tablet is right for you. The doctor will only prescribe Pfend 200mg Tablet after assessing your condition. Based on your response to treatment and tolerability, you should continue the medicine.

If my disease is stable, can I stop Pfend 200mg Tablet?

Idiopathic pulmonary fibrosis is a progressive disease, though its progression is unpredictable. Do not stop the medication without consulting the doctor. Continue taking Pfend 200mg Tablet to slow down the progression of the disease.

What should I avoid while taking Pfend 200mg Tablet?

You should restrict sun exposure while taking Pfend 200mg Tablet. Wear sunblock daily and cover your arms, legs, and head to reduce exposure to sunlight. Along with that, avoid smoking as it decreases the effect of Pfend 200mg Tablet.

What is the survival rate of pulmonary fibrosis?

The median survival of patients with pulmonary fibrosis is 2-3 years, yet some people live much longer. The factors that can be held responsible for shortened survival are older age, smoking history, and lower body mass index. The other factors can be a more severe extent of disease, both radiologically and physically, and the development of other lung complications or conditions.

Fact Box

Chemical Class

Pyridinones

Habit Forming

Therapeutic Class

RESPIRATORY

Action Class

Antifibrotic Agent

References

Pirefenidone. Brisbane, California: InterMune, Inc.; 2014. [Accessed 01 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
CiplaMed: Pirfenidone [Prescribing Information]. [Accessed 05 Aug. 2023] (online) Available from:
Pirfenidone [Summary of Product Characteristics]. Grenzach-Wyhlen, Germany: Roche Registration GmbH; 2015.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Remalthea Pharmaceuticals Private Limited
Address: R H No. 57 S No. 159 Apratim Vastu Aurangabad Aurangabad Mh 431001 India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Pfend 200mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Pfend 200mg Tablet

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Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pfend Tablet

Benefits of Pfend Tablet

Side effects of Pfend Tablet

How to use Pfend Tablet

How Pfend Tablet works

All substitutes for Pfend 200mg Tablet

Fibrodone Tablet

Pirfetab Tablet

Pulmofib 200mg Tablet

Pirfenex Tablet

Perfecine Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Fluvoxamine (Oral Route)

Axitinib (Oral Route)

Allylestrenol (Oral Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Frequently asked questions

What monitoring will I need during treatment with Pfend 200mg Tablet?

Why is it important to continue treatment with Pfend 200mg Tablet?

How do I know that Pfend 200mg Tablet is right for me?

If my disease is stable, can I stop Pfend 200mg Tablet?

What should I avoid while taking Pfend 200mg Tablet?

What is the survival rate of pulmonary fibrosis?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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