Pentone 1gm Injection

Thiopental Sodium (1gm)

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Pentone 1gm Injection is used for producing general anesthesia. It may also be used to reduce intracranial pressure.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)

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General Information

Contains

Thiopental Sodium (1gm)

Marketer

Chandra Bhagat Pharma Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pentone 1gm Injection is given as an injection in hospital settings under the supervision of a healthcare professional. It is important to provide medical history and inform your doctor if you are suffering from cardiovascular disease, asthma, or myasthenia gravis as special care is needed in administering this medicine to such patients.

Some common side effects of this medicine are skin rash or pain at the site of injection, nausea, vomiting, diarrhea, and vertigo. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus. You should avoid drinking alcohol or taking other medications that cause drowsiness after taking this medicine as it may result in serious effects. Ensure that you practice additional pregnancy control methods as this medicine may decrease the effectiveness of birth control pills.

Uses of Pentone Injection

Anesthesia

Benefits of Pentone Injection

Anesthesia
Pentone 1gm Injection is used to help patients fall asleep quickly before surgery or medical procedures. It allows for a smooth and fast onset of anesthesia, ensuring comfort and unconsciousness during operations.

Side effects of Pentone Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentone

Injection site reactions (pain, swelling, redness)
Drowsiness
Skin rash
Nausea
Vomiting
Diarrhea
Vertigo

How to use Pentone Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pentone Injection works

Pentone 1gm Injection is a general anaesthetic. It works by causing reversible loss of consciousness to allow surgery without pain and distress.

Quick tips

Pentone 1gm Injection is used to facilitate surgery without pain and distress.
It is given as an injection into veins under the supervision of a doctor.
It can cause severe drowsiness lasting for several hours. Do not drive or do anything that requires alertness for at least 24 hours.
Inform your doctor if you have liver disease, thyroid disorder, severe heart disease, severe low blood pressure or a severe breathing disorder.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Pentone 1gm Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pentone 1gm Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Pentone 1gm Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Pentone 1gm Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Pentone 1gm Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Pentone 1gm Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pentone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Domperidone (Oral Route)

Do not consume Thiopental Sodium with Domperidone.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Pimozide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Haloperidol (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Mizolastine (Oral Route)

Do not consume Thiopental Sodium with Mizolastine.

Frequently asked questions

What is Pentone 1gm Injection used for?

Pentone 1gm Injection is a medicine used to make you fall asleep quickly before surgery or medical procedures. It helps start (induce) general anesthesia. Doctors may also use it to control seizures or to lower pressure inside the brain in emergency situations.

Is Pentone 1gm Injection a painkiller?

No, Pentone 1gm Injection is not a pain‑relief medicine. It only helps you fall asleep or become unconscious for a short time. If pain control is needed, doctors usually give additional medicines along with it.

Can Pentone 1gm Injection cause breathing problems?

Yes. Pentone 1gm Injection can slow down or temporarily stop breathing if given too quickly or in a high dose. This is why it is always administered by trained medical professionals in a hospital or clinic setting where your breathing and heart rate are closely monitored.

Who should not receive Pentone 1gm Injection?

People with breathing problems (like severe asthma), severe shock, muscle disorders such as myotonic dystrophy, or a condition called porphyria should not receive this medicine. It is also not suitable for those who have had allergic reactions to barbiturates.

What precautions should be taken before using Pentone 1gm Injection?

Tell your doctor if you have liver or kidney disease, heart problems, dehydration, thyroid issues, diabetes, or are addicted to alcohol or other drugs. The dose of Pentone 1gm Injection may need to be adjusted to ensure safety during anesthesia.

Can Pentone 1gm Injection affect blood pressure or the heart?

Yes. Pentone 1gm Injection can cause a drop in blood pressure or a slowing of the heart rate. In rare cases, it may cause cardiac arrest, especially in people with heart or circulation problems. Your doctor will monitor these effects throughout the procedure.

What are some serious side effects of Pentone 1gm Injection I should be aware of?

Serious side effects of Pentone 1gm Injection include severe allergic reactions (rash, swelling, trouble breathing), breathing difficulty, very low blood pressure, irregular heartbeat, or prolonged drowsiness. If any of these occur after a procedure, seek medical help immediately.

Is Pentone 1gm Injection safe for people with liver or kidney problems?

Caution is required. Pentone 1gm Injection is processed by the liver and removed by the kidneys. If either organ is not working well, the doctor will reduce the dose and monitor closely to avoid side effects.

Can Pentone 1gm Injection cause long‑lasting effects after surgery?

Some people may feel sleepy, dizzy, or confused for a day after receiving Pentone 1gm Injection. It is best not to drive, use machines, or make important decisions for 24 hours after anesthesia.

Fact Box

Chemical Class

Thiobarbituric acid derivative

Habit Forming

Yes

Therapeutic Class

PAIN ANALGESICS

Action Class

Barbiturates

References

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chandra Bhagat Pharma Pvt Ltd
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071

Vendor Details

Country of origin: India

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Pentone 1gm Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Pentone Injection

Benefits of Pentone Injection

Side effects of Pentone Injection

How to use Pentone Injection

How Pentone Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Domperidone (Oral Route)

Amiodarone (Oral Route)

Pimozide (Oral Route)

Haloperidol (Oral Route)

Mizolastine (Oral Route)

Frequently asked questions

What is Pentone 1gm Injection used for?

Is Pentone 1gm Injection a painkiller?

Can Pentone 1gm Injection cause breathing problems?

Who should not receive Pentone 1gm Injection?

What precautions should be taken before using Pentone 1gm Injection?

Can Pentone 1gm Injection affect blood pressure or the heart?

What are some serious side effects of Pentone 1gm Injection I should be aware of?

Is Pentone 1gm Injection safe for people with liver or kidney problems?

Can Pentone 1gm Injection cause long‑lasting effects after surgery?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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