Pentanerv 450mg Tablet SR is a medicine used to relieve the pain caused by nerve damage (neuropathic pain) due to various conditions like diabetes, shingles (herpes zoster infection), spinal cord injury, etc. It is also used to treat certain types of seizures (fits) in combination with other medicines.
Pentanerv 450mg Tablet SR belongs to the anti-epileptic group of medicines. You may take it with or without food, but it is important to take this medicine at the same time each day to get the most benefit. The exact dose and duration of treatment will depend on your condition and how you respond to it. Your doctor will probably start this medicine at a low dose and increase it gradually. It may take a few weeks for the medicine to work properly. Follow your doctor’s instructions and continue taking it regularly until your doctor advises you to stop. Do not miss any dose, otherwise, your condition may worsen.
Most people taking Pentanerv 450mg Tablet SR do not experience any side effects. The most common ones are feeling sleepy, dizzy, or tired (fatigue). These are usually mild and go away by themselves as your body gets used to the medicine. Most side effects are not serious and do not need medical attention. Talk to your doctor if any of the side effects persist or worry you.
You should avoid drinking alcohol along with this medicine as it may lead to excessive sleepiness and dizziness. Let your doctor know right away if you develop any unusual mood changes like anxiety, agitation, depression, or thoughts about harming yourself.
Before taking Pentanerv 450mg Tablet SR, you should tell your doctor if you have any kidney-related problems or if you are more than 65 years old. Your doctor may prescribe a different dose in such people. Women who are pregnant, breastfeeding, or planning to become pregnant should also consult their doctor before using this medicine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pentanerv
Impaired coordination
Viral infection
Sleepiness
Dizziness
Fatigue
Fever
How to use Pentanerv Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentanerv 450mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.
How Pentanerv Tablet SR works
Pentanerv 450mg Tablet SR is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve pain where it blocks pain by interfering with pain signals traveling through the damaged nerves and the brain.
Safety advice
Alcohol
UNSAFE
Pentanerv 450mg Tablet SR may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Pentanerv 450mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pentanerv 450mg Tablet SR is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Baby should be monitored for excessive sleepiness and weight gain.
Driving
UNSAFE
Pentanerv 450mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Pentanerv 450mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Pentanerv 450mg Tablet SR may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Pentanerv 450mg Tablet SR in patients with liver disease. Please consult your doctor.
What if you forget to take Pentanerv Tablet SR?
If you miss a dose of Pentanerv 450mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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I have radiating pain on the top right area of my head. I have been having this pain since the last 4 days.i am unable to touch that area of my head due to the pain. The pain is only on the area where I have hair growth. I also have the radiating pain on the back of my neck -right part. I have been diagnosed with cervical spondylosis previously. Last 2 weeks back I recovered from dengue fever.
anxiety high blood pressure sleep problems seizures
Dr. Jyoti Kapoor Madan
Psychiatry
Anxiety is the result of a hyperarousal state of nervous system due to a low threshold for threat perception. In simpler words, it's an ongoing flight or fight response. It can elicit a neuro-hormonal response understood as Flight or Fright reaction kicking in physiological cascade of symptoms ranging from palpitations, tachycardia, breathlessness, increased bowel movement, increase frequency of urination, dizziness, muscle tension or pain, trembling, dizziness, blurring of vision to restlessness, confusion and fainting spells. Chronic stress causes prolonged anxiety response with the consequences of slowed me ration, lack of concentration, headaches, fluctuations in blood pressure and increased wear and tear of body tissues. Identifying your stressors, learning to deal with them, de stressing regularly by doing something that makes one feel good, yoga and meditation are some non pharmacological strategies to deal with it. Siezures are due to electrophysiological disturbance in brain and anti convulsants are the treatment of choice. If the condition is persisting for a long time, it's better to see a psychiatrist.
with hypertension or weakness make the sezir more about 3 time in 6 month
Dr. Jyoti Kapoor Madan
Psychiatry
Seizures are caused by electro physiological activity in brain. Stress and anxiety may often increase pseudo seizures. Very rarely, epileptic fits are triggered off by stress.
What were the side-effects while using Pentanerv 450mg Tablet SR?
Fatigue
25%
Dizziness
25%
Sleepiness
25%
No Side Effec*
25%
*No Side Effect
How do you take Pentanerv Tablet SR?
With or witho*
67%
With food
33%
*With or without food
Please rate Pentanerv 450mg Tablet SR on price
Not Expensive
78%
Average
22%
FAQs
I have been prescribed Pentanerv 450mg Tablet SR for pain. When will I start feeling better?
It varies from person to person. Some people take about a week or two before noticing relief in pain. Whereas, some people may see an improvement straight away. It is recommended that you take Pentanerv 450mg Tablet SR only for nerve pain and as advised by your doctor.
I think I have gained weight since I started taking Pentanerv 450mg Tablet SR. Can this be because of Pentanerv 450mg Tablet SR?
Yes, Pentanerv 450mg Tablet SR may cause weight gain because it increases your hunger. Regular physical exercise and a balanced diet with low calorie food may help you maintain a stable weight. Consult a dietitian if you have any further concerns to keep your weight stable.
For how long do I need to take Pentanerv 450mg Tablet SR?
Your doctor will decide the duration of the treatment based on your condition and your response to the treatment. For instance, if you have been prescribed Pentanerv 450mg Tablet SR for epilepsy, you may have to take it for a long time, maybe years even if your seizures are controlled. Whereas, if you are taking it for nerve pain and it has relieved your pain, you may have to take it for several months only.
What are the serious side effects that may occur while taking Pentanerv 450mg Tablet SR?
Taking Pentanerv 450mg Tablet SR may cause yellowing of the skin or eyes (warning signs of jaundice), trouble in breathing or talking and tightness in chest or throat (suggestive of serious allergic skin reactions). It may provoke suicidal thoughts and cause unusual bruises or bleeding which may be due to blood disorder. Other serious side effects may include muscle weakness and pain, fever which could lead to kidney failure, long-lasting stomach pain, nausea and vomiting (suggestive of pancreatitis and rash).
Is Pentanerv 450mg Tablet SR habit forming?
No, it will not be addictive if you take it as per your doctor’s recommendations. However, physical dependence has been reported in people who had taken more than the recommended dose of Pentanerv 450mg Tablet SR or had used Pentanerv 450mg Tablet SR for illnesses it is not approved for.
I am taking Pentanerv 450mg Tablet SR for nerve pain. Can I take it off and on?
No, Pentanerv 450mg Tablet SR is not a simple pain reliever. It is important that you follow your doctor’s advice strictly. Taking it off and on may not give you the desired results and may worsen your pain.
What if somebody takes more than the recommended dose of Pentanerv 450mg Tablet SR?
A higher than the recommended dose of Pentanerv 450mg Tablet SR may cause faintness, dizziness, double vision, unclear speech, drowsiness, tiredness and mild diarrhea. The person requires immediate medical attention by a doctor or in a nearby hospital.
What should I tell my doctor before taking this medicine?
Inform your doctor if you are taking any other medicines including medicines for epilepsy or seizures, medicines used to thin your blood (e.g., warfarin), birth control pills, medicines to control bacterial infection (e.g., chloramphenicol, metronidazole, and doxycycline), medicines to control viral infection (e.g., nelfinavir), asthma medicines (e.g., theophylline and montelukast), etc. Also, inform your doctor if you are planning to become pregnant or are breastfeeding. Further, you should tell the doctor if you have ever had liver problems, kidney problems, lung problems, or porphyria (a rare blood pigment disorder).
What should I avoid while taking Pentanerv 450mg Tablet SR?
If Pentanerv 450mg Tablet SR makes you feel sleepy, avoid driving or operating heavy machinery. Alcohol consumption should be avoided since taking both together may cause excessive sleepiness.
Does Pentanerv 450mg Tablet SR reduce the efficiency of oral birth control pills?
No, Pentanerv 450mg Tablet SR does not have any effect on oral birth control pills.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Stahl SM, editor. Gabapentin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 275-77.
McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 599.
Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 410.
Gabapentin. Menlo Park: Depomed; 1993 [revised date]. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Gabapentin. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Texas Vendor Drug Program. Drug Use Criteria: Gabapentin. [Accessed 28 June 2023]. (online) Available from:
National Health Service. Pregnancy, breastfeeding and fertility while taking gabapentin. [Last Revised: 18 Jan. 2022]. [Accessed 28 June 2023]. (online) Available from:
Country of origin: India Expires on or after: October, 2025
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