Medicine Overview of Path Tablet
Path 30 mg Tablet is used in the treatment of type 2 diabetes
. It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Side Effects of Path are Weight gain, Blurred vision, Respiratory tract infection, Numbness, Bone fracture.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Path 30 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Path 30 mg Tablet is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.
In Depth Information on Path Tablet
Path 30 mg Tablet helps to control blood sugar level and avoids long-term complications.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Path 30 mg Tablet.
Full effect may be visible after several weeks of starting Path 30 mg Tablet.
Weight gain, headache, and swelling due to fluid build-up may occur.
- Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
May not be suitable for patients with a history of heart failure or bladder cancer.
Path Tablet related warnings
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
WEIGH RISKS VS BENEFITS
Path 30 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Path 30 mg Tablet is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Path 30 mg Tablet
Path 30 mg Tablet does not usually affect your ability to drive.
Path 30 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Path 30 mg Tablet is recommended.
Use of Path 30 mg Tablet is not recommended in patients undergoing dialysis.
Path 30 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Path 30 mg Tablet may be needed. Please consult your doctor.
Use of Path 30 mg Tablet is not recommended in patients with severe liver disease.
If you miss a dose of Path 30 mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Frequently asked questions about Path Tablet
Q. Is Path a blood thinner?
No. Path is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.
No. Path is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.
Q. Can Path used in Hepatitis B infection?
Some studies have shown that Path may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.
Q. Can Path used in Hepatitis C infection?
Path has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.
Q. Can Path used along with Vitamin D?
Studies indicate that Vitamin-D combined with Path may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Path alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).
Q. Can Path be used along with sitagliptin?
Combination therapy with Sitagliptin and Path leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Path alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.
Q. Is there any role of Path in Alzheimer disease?
Recent evidence suggests that Path may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.
Q. Can Path and repaglinide combined in diabetes treatment?
For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Path have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.
Q. Does Path cause urinary bladder tumour?
Large population studies indicate that Path is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.
Q. Can Path be used along with glimepiride in diabetes?
Path when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.
No. Path is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.
Path is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Path acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.
Path cardiovascular safety profile compares favourably with that of Rosiglitazone. Path has been found to be associated with bladder tumours but causality assessment has not been proved yet.
Q. How does Path cause oedema?
Path increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Path causes increased sodium and water reabsorption from the kidney that contributes to the oedema.
Q. How does Path cause bladder cancer?
The mechanism behind the link between Path use and bladder cancer is still unknown. Studies have suggested that use of Path for more than one year results in increased risk of development of tumour of the urinary bladder.
Q. How Path protects against atherosclerosis?
Studies in animals have concluded that Path improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.
Q. Can Path be used with insulin?
The addition of Path reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.
Q. Can Path used for dementia?
Findings indicate that Path treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.
Q. Can Path used for infertility?
Path may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.
Q. Can Path used for psoriasis?
The use of Path for plaque psoriasis treatment is controversial. Some studies revealed no effect of Path 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.
Q. Can Path used for autism?
In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Path for 3–4 months induced apparent clinical improvement. Path should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Path use.
Q. Can Path be used in depression?
Path, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.
Q. Can Path used for weight loss?
A recent study shows that although Path causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.
Q. Can Path be used to treat fatty liver?
Path has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
Q. Can Path be used for secondary stroke prevention?
Path reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
Severely interacts with other drugs like
Taking Path with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Trimethoprim: Tmp
Medicines with composition Paroxetine: Leparox, Prx, Paromec, Madotine, Parolyst, Parox, Baxidep, Psypro, Parot, Proxzen
Medicines with composition Glucosamine: Carizen, Gluconol, HGM, Glucomove, Cartimax, Joinix, Fleximax, Kondro, Reostin, Viartril
Medicines with composition Citalopram: Vocita, Celexa, Olarc, Citopam
Medicines with composition Diastase: Figozyme
Medicines with composition Orlistat: Orli-Misia, Redufat, Orlistat, Orlibee, Relap, Orlimac, O Trim, Safe Slim, O-Stat, Orlimax
Medicines with composition Collagen Peptide: Nudiglue-C
Medicines with composition Triamcinolone: Darcort, Trilone, Mycort, Presticort-T, Tacit, Alcicort, Kapiswit, Trilon, Stancort, Oraways
Medicines with composition Escitalopram: Kopram, Ecit, Escnx, Esitopa, Madito, Citolex, Elcit, Escivi, Esetinol, Esmood
Medicines with composition Budesonide: Budojet, Budemon, Budate, Bunase, Derinide, Budecort, Derinide AQ, Budeflam AQ, Pulmicort
Medicines with composition Dapoxetine: Actinex, DA Sutra, Stay Tal, Dapoxy, Dapnex, Duraject, Appynite
Medicines with composition Clonidine: Arkamin
Medicines with composition Betamethasone: Catrisol, Betaforte, Betacon, Betalide, Becort, Betastamine, Ascort, Betachlor, Betan, Betapar
Medicines with composition Insulin Lispro: Humalog
Medicines with composition Fluorometholone: FMN, Fluorobell, Zyflace, Biflace, Flurocot, Flomex, Flumace, Lon
Medicines with composition Spironolactone: Aldactone
Medicines with composition Pindolol: Visken
Medicines with composition Fluoxetine: Flotin, Fluxen, Fluty, FT, Depilox, Bydep, Afzot, Ulaxy, Flurix, Tune
Medicines with composition Metolazone: Metoz, Diurem, Zytanix
Medicines with composition Dexamethasone: Dexamax, OD Dex, Adexa, Dexaril, Dexarain, Dexalide, Dexton, Dekadin, Pfidex, Dexacron
Medicines with composition Chlorthalidone: Chlornol, Thiovas, Chlorfid, Lupiclor, Klorzid, Clovet, Thaloric, Thiaklor, Zione
Medicines with composition Diacerein: Acert, Dipain, Dircin, Rayce, Racrin, Dik, Dicerex, Diasmin, Ulcerin, Inosteo
Medicines with composition Octreotide acetate: Octotide, Octride, Sandostatin LAR, Octate, Varioct, Actide, Otide, Ferotide
Medicines with composition Gemfibrozil: Losterol, Oxipace, Lopid
Medicines with composition Deflazacort: Ducort, Defmark, Zacdef, Ecodef, Defalone, Renze, Jeevcort, Flazassil, Exacort, Solo D
Medicines with composition Pancreatin: Digeplex T, Enzabil, Enzelo, Aflate N, Panstal N, Panzynorm-HS, Farizyme, Lapin
Medicines with composition Propranolol: Psycool, Proparise, Poplol, Capinol LA, Ranol, Reylol, Betapill, Zopilar, Bptab, Betasav
Medicines with composition Methylprednisolone: Zencort-M, Welone, Rigapred, Premeth, Lumi M, Mep, Aricort M, Metcort, Ultrapred, Meprosol
Medicines with composition Fenofibrate: Finograt, Fenoca TG, Golip, Lipicard, Trichek, Fenolip, Stanlip, Fenocard, Fibral, Fenodac
Medicines with composition Hydrocortisone: Stacort, Maxicort, Geocort, Cortimet, Cortis H, Hyss, Raghucort, Cortilup, Primacort, Hydrocort
Medicines with composition Indapamide: Excrete, Indizon, Indicard, Inklud, Natritor, Lorvas, Natrilix, Diurix, Insuretis, Inditor
Medicines with composition Insulin Glulisine: Apidra
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