Parbraze 150mg Tablet
Prescription Required
Product introduction
Parbraze 150mg Tablet is a prescription medicine used in the treatment of ovarian and breast cancer. It works by blocking an enzyme called PARP, which helps fix damaged DNA. By stopping PARP, the medicine prevents cancer cells from repairing themselves, leading them to die off and slowing tumor growth.
Parbraze 150mg Tablet may be taken with or without food. Swallow the tablets whole, without crushing, chewing, or splitting them. Take it regularly and at the same time every day to maintain an even level of the medication in your body. Follow your doctor’s instructions on the exact dosage and schedule.
Common side effects include nausea, fatigue, vomiting, loss of appetite, diarrhea, and dizziness. If you experience nausea or vomiting, eating smaller, more frequent meals and staying hydrated can help. Inform your doctor if these side effects become severe or do not go away. Be cautious about driving or operating heavy machinery if you feel dizzy or fatigued.
While taking Parbraze 150mg Tablet, avoid consuming grapefruit or grapefruit juice as it can increase the risk of side effects. This medicine can cause harm to an unborn baby, so it is important to use effective contraception during treatment and for some time after the last dose. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Regular blood tests are needed to monitor your blood cell counts and liver function during treatment. Do not start any new medications or supplements without consulting your doctor, as they may interact with Parbraze 150mg Tablet.
Uses of Parbraze Tablet
Benefits of Parbraze Tablet
In Treatment of Breast cancer
Parbraze 150mg Tablet provides a targeted treatment option that specifically attacks cancer cells while sparing most healthy cells. Clinical studies have shown that Parbraze 150mg Tablet can significantly reduce the risk of cancer progression or recurrence and improve survival rates. By specifically inhibiting the PARP enzyme in cancer cells, Parbraze 150mg Tablet helps to slow the spread of the disease, providing patients with a more effective and less toxic treatment option.
In Treatment of Ovarian cancer
Parbraze 150mg Tablet helps prevent the cancer from worsening for a longer period. The medicine is effective in both newly diagnosed cases and in recurrent ovarian cancer, offering a maintenance therapy option that can delay the need for further chemotherapy. This targeted therapy can lead to better management of the disease with a more personalized approach, improving overall outcomes and quality of life for patients.
Side effects of Parbraze Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Parbraze
- Nausea
- Vomiting
- Fatigue
- Diarrhea
- Loss of appetite
- Anemia (low number of red blood cells)
- Headache
- Decreased blood cells (red cells, white cells, and platelets)
- Taste change
- Cough
- Breathlessness
- Indigestion
- Abdominal pain
How to use Parbraze Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Parbraze 150mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Parbraze Tablet works
Parbraze 150mg Tablet is an anticancer medication. It works by inhibiting the growth of select tumor cell lines in vitro and decrease tumor growth in both as monotherapy or following chemotherapy.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Parbraze 150mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Parbraze 150mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Parbraze 150mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Parbraze 150mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Parbraze 150mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Parbraze 150mg Tablet is recommended.
Liver
SAFE IF PRESCRIBED
Parbraze 150mg Tablet is safe to use in patients with liver disease. No dose adjustment of Parbraze 150mg Tablet is recommended.
What if you forget to take Parbraze Tablet?
If you miss a dose of Parbraze 150mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Parbraze 150mg Tablet
₹334.13/Tablet
Obrenza 150 Tablet
Sun Pharmaceutical Ind Ltd
₹378.68/tablet
13% costlier
Obparp 150 Tablet
Cipla Ltd
₹238.63/tablet
29% cheaper
Lynparza 150mg Tablet
AstraZeneca
₹4436.25/tablet
1228% costlier
Olzapar 150mg Tablet
Delarc Pharmaceuticals Private Limited
₹924.18/tablet
177% costlier
Brcaone 150mg Tablet
Emcure Pharmaceuticals Ltd
₹668.25/tablet
100% costlier
Quick tips
- Take Parbraze 150mg Tablet exactly as prescribed by your doctor. Do not alter your dose without consulting your doctor.
- Drinking plenty of fluids can help reduce some side effects, such as nausea and vomiting. Try to drink at least 8-10 glasses of water each day.
- Parbraze 150mg Tablet can affect your blood cell counts. Ensure you have regular blood tests as recommended by your doctor to monitor for potential issues like anemia or low white blood cell counts.
- Parbraze 150mg Tablet can harm an unborn baby. Women should use effective contraception during treatment and for a period after the last dose. Men with female partners of reproductive potential should also use effective contraception during treatment and for a specified time afterward.
- Maintain a healthy lifestyle by eating a balanced diet, getting regular exercise, and managing stress. This can help improve your overall well-being during treatment.
Fact Box
Chemical Class
Pthalazinone derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Interaction with drugs
Taking Parbraze with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Carbamazepine may reduce blood levels of Olaparib.
Do not consume Olaparib with Carbamazepine.
Fosphenytoin may reduce blood levels of Olaparib.
Do not consume Olaparib with Fosphenytoin.
Phenobarbitone may reduce blood levels of Olaparib.
Do not consume Olaparib with Phenobarbitone.
Apalutamide may reduce blood levels of Olaparib.
Do not consume Olaparib with Apalutamide.
Phenytoin may reduce blood levels of Olaparib.
Do not consume Olaparib with Phenytoin.
Patient concerns
FAQs
What is Parbraze 150mg Tablet?
Parbraze 150mg Tablet is a prescription medication used to treat ovarian and breast cancer. It works by blocking an enzyme involved in repairing damaged DNA, thereby helping to kill cancer cells.
What should I tell my doctor before starting Parbraze 150mg Tablet?
Before starting Parbraze 150mg Tablet, inform your doctor about any other medications you are taking, any allergies, and your medical history, especially if you have kidney or liver problems, lung issues, or are planning to become pregnant or are breastfeeding.
Can Parbraze 150mg Tablet be taken with other medications?
Some medications may interact with Parbraze 150mg Tablet, affecting how it works or increasing the risk of side effects. Always inform your doctor about all the medications and supplements you are taking to ensure there are no harmful interactions.
Is Parbraze 150mg Tablet safe to use during pregnancy or while breastfeeding?
Parbraze 150mg Tablet can harm an unborn baby. It is important to avoid pregnancy while taking Parbraze 150mg Tablet and for a period after the last dose. Women should use effective contraception during treatment and for a specified time after the last dose. Breastfeeding is not recommended during treatment with Parbraze 150mg Tablet and for a period after the last dose.
How long will I need to take Parbraze 150mg Tablet?
The duration of treatment varies depending on the type of cancer being treated, the patient’s response to the medication, and the presence of any side effects. Your doctor will determine the appropriate length of treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Cancer Research UK. Olaparib (Lynparza). [Accessed 17 Jul. 2024] (online) Available from:
- Olaparib [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020. [Accessed 17 Jul. 2024] (online) Available from:
- Lynparza (Olaparib) [Product Information]. [Accessed 17 Jul. 2024] (online) Available from:
- Lynparza (Olaparib) [Product Information]. [Accessed 17 Jul. 2024] (online) Available from:
- Olaparib [Prescribing Information]. London, UK: AstraZeneca UK Limited; 2023. [Accessed 17 Jul. 2024] (online) Available from:
- Olaparib [Summary of Product Characteristics]. Södertälje, Sweden: AstraZeneca AB; 2022. [Accessed 17 Jul. 2024] (online) Available from:
- Olaparib [Prescribing Information]. Mississauga, Ontario: AstraZeneca Canada Inc. 2024. [Accessed 17 Jul. 2024] (online) Available from:
Marketer details
Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Country of origin: India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Parbraze 150mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Parbraze 150mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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