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Olaparib

Written By Dr. Swati MishraReviewed By Dr. Rajeev Sharma
Last updated 25 Nov 2025 | 09:34 AM (UTC)

Olaparib Uses

Olaparib is used in the treatment of ovarian cancer and breast cancer.

How Olaparib works

Olaparib is an anticancer medication. It works by inhibiting the growth of select tumor cell lines in vitro and decrease tumor growth in both as monotherapy or following chemotherapy.

Common side effects of Olaparib

Nausea, Vomiting, Fatigue, Diarrhea, Loss of appetite, Headache, Anemia (low number of red blood cells), Decreased blood cells (red cells, white cells, and platelets), Taste change, Cough, Breathlessness, Indigestion, Abdominal pain
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Expert advice for Olaparib

  • Take Olaparib exactly as prescribed by your doctor. Do not alter your dose without consulting your doctor.
  • Drinking plenty of fluids can help reduce some side effects, such as nausea and vomiting. Try to drink at least 8-10 glasses of water each day.
  • Olaparib can affect your blood cell counts. Ensure you have regular blood tests as recommended by your doctor to monitor for potential issues like anemia or low white blood cell counts.
  • Olaparib can harm an unborn baby. Women should use effective contraception during treatment and for a period after the last dose. Men with female partners of reproductive potential should also use effective contraception during treatment and for a specified time afterward.
  • Maintain a healthy lifestyle by eating a balanced diet, getting regular exercise, and managing stress. This can help improve your overall well-being during treatment.

Frequently asked questions for Olaparib

Olaparib is a prescription medication used to treat ovarian and breast cancer. It works by blocking an enzyme involved in repairing damaged DNA, thereby helping to kill cancer cells.
Before starting Olaparib, inform your doctor about any other medications you are taking, any allergies, and your medical history, especially if you have kidney or liver problems, lung issues, or are planning to become pregnant or are breastfeeding.
Some medications may interact with Olaparib, affecting how it works or increasing the risk of side effects. Always inform your doctor about all the medications and supplements you are taking to ensure there are no harmful interactions.
Olaparib can harm an unborn baby. It is important to avoid pregnancy while taking Olaparib and for a period after the last dose. Women should use effective contraception during treatment and for a specified time after the last dose. Breastfeeding is not recommended during treatment with Olaparib and for a period after the last dose.
The duration of treatment varies depending on the type of cancer being treated, the patient’s response to the medication, and the presence of any side effects. Your doctor will determine the appropriate length of treatment.