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Opipran 50 Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 21 Sep 2025 | 09:56 PM (IST)
Opipran 50 Tablet is a prescription medicine used in the treatment of anxiety disorders. It also helps in restoring the messengers that elevate the mood.
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Opipran 50 Tablet is currently sold out
Same composition alternative:
OPIprol 50 Tablet
₹93.3₹101.25
Available alternative from Sun Pharmaceuticals
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Opipran 50 Tablet
Opipran 50 Tablet
strip of 10 tablets
₹59.3
₹65.63
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Same composition
OPIprol 50 Tablet
OPIprol 50 Tablet
strip of 10 tablets
by Sun Pharmaceutical Industries Ltd
Get in 30 mins
₹93.3
₹7.93 per tablet

₹79.3

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₹1200

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General Information

The content is shown in English
Opipran 50 Tablet image
Opipran 50 Tablet image

Product introduction

Opipran 50 Tablet may be taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor, as it may worsen your symptoms.


Some common side effects of this medicine include nasal congestion, fatigue, and dryness in the mouth. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.


It is important to inform your doctor if you develop any unusual mood changes, as it may lead to suicidal thoughts. If you have been taking this medicine for a long time, regular monitoring of liver function may be required. Inform your doctor if you have any health conditions associated with the liver, kidneys, or heart. Tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding before taking Opipran 50 Tablet.

Uses of Opipran Tablet

Benefits of Opipran Tablet

Anxiety disorder
Opipran 50 Tablet is primarily used to treat anxiety disorders. It works by balancing neurotransmitters like serotonin and dopamine, promoting a calming effect and improving mood. Unlike conventional medicine, Opipran 50 Tablet has mild sedative properties, making it effective for anxiety-related sleep disturbances. It is well-tolerated, with a lower risk of dependency compared to other sedative medicines (like benzodiazepines). This medication helps reduce excessive worry, restlessness, and physical symptoms of anxiety, improving overall quality of life. Regular medical supervision is advised to ensure safe and effective use.

Side effects of Opipran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Opipran
  • Weight gain
  • Fatigue
  • Dryness in mouth
  • Hypotension (low blood pressure)
  • Raised itchy skin rash

How to use Opipran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Opipran 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Opipran Tablet works

Opipran 50 Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treating depression.

Quick tips

  • Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking this medicine, as it may cause excessive sleepiness or drowsiness.
  • Your doctor may monitor your blood counts and liver function regularly. Inform your doctor if you develop fever, stomach pain, nausea, or yellowing of your eyes or skin.
  • Inform your doctor if you are pregnant or breastfeeding, or if you notice changes in your mood or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor first.

Safety advice

Alcohol

Alcohol

UNSAFE
Opipran 50 Tablet may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Opipran 50 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Opipran 50 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Opipran 50 Tablet may cause side effects which could affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Opipran 50 Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Opipran 50 Tablet in patients with liver disease. Please consult your doctor.

Interaction with drugs

Taking Opipran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Moclobemide (Oral Route)

Do not consume Moclobemide with Opipramol. If Moclobemide is essential, ensure a gap of at least 1 day after discontinuing Opipramol. Please consult your doctor.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Opipramol.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Opipramol. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Opipramol. Please consult your doctor.
Severe

Tramadol (Injection Route)

Careful consideration is advised if you have epilepsy. Watch out for symptoms of serotonin syndrome, such as sedation, respiratory impairment, tremors, fever, diarrhea, or agitation, and consult your doctor if you experience them. Your doctor may alter or discontinue the medicines accordingly.
Severe

Thioridazine (Oral Route)

If concurrent use is essential, watch out for symptoms such as sleepiness, dry mouth, impaired voluntary movements, weight gain, constipation, muscle stiffness or tremors and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Opipran 50 Tablet is used to treat anxiety disorder. It works by balancing the chemicals that regulate mood.
The exact time Opipran 50 Tablet takes to show results is not known. However, you may notice improvement in your mood in a few weeks. The full benefits may take longer depending upon the condition and how severe it is.
It is best to avoid alcohol while taking Opipran 50 Tablet. Alcohol can increase drowsiness, make you feel dizzy, and may reduce the effectiveness of the medication.
Weight gain is not common with Opipran 50 Tablet, but some people may experience changes in weight. It is a good idea to monitor your weight regularly, such as once a month, and discuss any noticeable changes with your doctor.
Your doctor may adjust your dose based on how well you are tolerating the medication, how effective it is for your symptoms, and the levels of Opipran 50 Tablet in your blood (in some cases).
Individuals should avoid taking Opipran 50 Tablet if they have a sudden inability to empty the bladder, sudden confusion or disorientation, a sudden increase in eye pressure causing severe eye pain and vision problems, an enlarged prostate that leaves urine in the bladder after peeing, intestinal blockage due to poor gut muscle movement, and problems with the heart's electrical signals affecting normal heartbeats. Always talk to your doctor to ensure Opipran 50 Tablet is safe for your specific health conditions.

Fact Box

Chemical Class

Dibenzazepines Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Tricyclic Antidepressants (TCAs)
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ryon Pharma
Address: Village Ajnoud Ludhiana - 141421, Punjab, India

Vendor Details

Country of origin: India
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