


Oleptiss 180mg Tablet DT
Deferasirox (180mg)
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Oleptiss 180mg Tablet DT is a medicine used in the treatment of chronic iron overload caused by frequent blood transfusion. It helps remove the excess iron from the body and reduce the risk of it causing organ damage.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Nov 2026 | 01:03 AM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Nov 2026 | 01:03 AM (IST)
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General Information
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Product introduction
Oleptiss 180mg Tablet DT should be taken on an empty stomach. Take it in the exact dose and duration and take it regularly at a fixed time each day to get the maximum benefit from it.
Using of Oleptiss 180mg Tablet DT may cause common side effects such as nausea, headache, constipation, and diarrhea. If the side effects persist or worsen, inform your doctor.
Before using this medicine, let your doctor know if you have any kidney or liver diseases. Let your doctor also know about all the other medicines you are taking to ensure your safety.
Uses of Oleptiss Tablet DT
Benefits of Oleptiss Tablet DT
Treatment of Iron overload
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Oleptiss 180mg Tablet DT, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Oleptiss 180mg Tablet DT as prescribed by the doctor to get the maximum benefit.
Iron overload, as the name suggests, means excess of iron in the human body. Too much iron can cause organ damage, which can lead to conditions such as cancer, irregular heartbeat and cirrhosis of the liver. Symptoms are related to conditions that arise from iron overload such as high blood sugar levels (diabetes), darkening of the skin, abnormal heart rhythm or arthritis. By using Oleptiss 180mg Tablet DT, this excess of iron can be decreased to safe levels by removing it from the body through stools. This helps to reduce the risk of organ damage and prevents further complications. Take Oleptiss 180mg Tablet DT as prescribed by the doctor to get the maximum benefit.
Side effects of Oleptiss Tablet DT
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oleptiss
- Increased creatine level in blood
How to use Oleptiss Tablet DT
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Oleptiss 180mg Tablet DT is to be taken on an empty stomach.
How Oleptiss Tablet DT works
Oleptiss 180mg Tablet DT traps and removes excess iron which is then excreted mainly in the stools. This reduces the risk of organ damage.
Quick tips
- Oleptiss 180mg Tablet DT is used to reduce excess iron from the body.
- Inform your doctor if you also have upper stomach pain, clay-colored stools, or jaundice (yellowing of your skin or the whites of your eyes).
- Take an adequate amount of water while taking Oleptiss 180mg Tablet DT.
- Oleptiss 180mg Tablet DT may cause dizziness. It is advisable not to drive or operate any machinery until you feel normal again.
- If you are taking any antacid, take them 2 hours before or after Oleptiss 180mg Tablet DT.
- Inform your doctor if you have any liver or kidney disease.
- Inform your doctor if you are pregnant or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Oleptiss 180mg Tablet DT. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Oleptiss 180mg Tablet DT is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CAUTION
Oleptiss 180mg Tablet DT should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
CONSULT YOUR DOCTOR
It is not known whether Oleptiss 180mg Tablet DT alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
CAUTION
Oleptiss 180mg Tablet DT should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Oleptiss 180mg Tablet DT should be used with caution in patients with liver disease. Dose adjustment may be needed.
Interaction with drugs
Taking Oleptiss with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Acenocoumarol (Oral Route)
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Moderate
Dexamethasone (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Dexamethasone (Injection Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Moderate
Magaldrate (Oral Route)
Do not consume Deferasirox with Magaldrate. If concurrent use is essential, please consult your doctor.
Moderate
Methylprednisolone (Oral Route)
Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine).
Frequently asked questions
Oleptiss 180mg Tablet DT is used to treat chronic iron overload caused by repeated blood transfusions and certain conditions associated with excess iron. It helps remove excess iron from the body and may reduce the risk of organ damage.
Take Oleptiss 180mg Tablet DT exactly as prescribed by your doctor. It is usually on an empty stomach unless advised otherwise.
Yes. Oleptiss 180mg Tablet DT can cause stomach or intestinal ulcers and bleeding, which can sometimes be serious. Seek urgent medical attention if you develop severe stomach pain, vomit blood or material that looks like coffee grounds, or pass black, tarry stools.
Yes. Regular monitoring is essential. Your doctor may check kidney and liver function, blood counts, and iron levels, and arrange hearing and eye examinations. Attend all scheduled appointments so that your treatment can be adjusted safely.
Tell your doctor about all medicines and supplements you take. Do not take Oleptiss 180mg Tablet DT with aluminium-containing antacids. It can also interact with certain painkillers, blood thinners, and other medicines, potentially increasing the risk of side effects. Check with your doctor before starting any new medicine.
A mild rash can occur, but Oleptiss 180mg Tablet DT can also cause rare, serious skin reactions. Seek immediate medical attention if you develop blistering, peeling skin, sores in the mouth, or swelling of the face or throat. Do not ignore a new or worsening rash.
Do not stop treatment or change your dose without consulting your doctor. Your doctor will monitor your iron levels and decide whether treatment should continue or the dose needs to be adjusted.
Fact Box
Chemical Class
Phenyl- 1,2,4- triazoles
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Iron Chelators
Related lab tests
References
- Byrns MC, Penning TM. Environmental Toxicology: Carcinogens and Heavy Metals. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1875-76.
- Kosnett MJ. Heavy Metal Intoxication & Chelators. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1010.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 365.
- Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 6 Apr. 2019] (online) Available from:
- Deferasirox. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2006 [revised 23 Jul. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:
- Deferasirox [Prescribing information]. Ascend Laboratories, LLC; 2024. [Accessed 26 Oct 2026] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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