Nublexa Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Nublexa Tablet is a Tyrosine kinase inhibitors used in the treatment of cancer of colon and rectum.

Nublexa Tablet should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include infection, low blood platelets, anemia, decreased appetite, hemorrhage, and high blood pressure. It can also cause voice change, diarrhea, stomatitis, vomiting, nausea, bilirubin in urine, increased liver enzyme,  rash, weakness, pain, fever, mucosal inflammation, and weight loss. If any of these side effects bother you, let your doctor know. Regular blood tests are required to check your blood cells along with liver functioning.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Nublexa Tablet

Benefits of Nublexa Tablet

In Cancer of colon and rectum

Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Nublexa Tablet treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Nublexa Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nublexa

  • Infection
  • Low blood platelets
  • Anemia (low number of red blood cells)
  • Rash
  • Weakness
  • Vomiting
  • Pain
  • Nausea
  • Fever
  • Diarrhea
  • High blood pressure
  • Decreased appetite
  • Mucosal inflammation
  • Stomatitis (Inflammation of the mouth)
  • Increased liver enzymes
  • Weight loss
  • Voice change
  • Bilirubin in urine

How to use Nublexa Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nublexa Tablet is to be taken with food.

How Nublexa Tablet works

Nublexa Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nublexa Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nublexa Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Nublexa Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nublexa Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Nublexa Tablet is safe to use in patients with kidney disease. No dose adjustment of Nublexa Tablet is recommended.
However, limited information is available on use of Nublexa Tablet in patients with severe kidney disease.
Liver
CAUTION
Nublexa Tablet should be used with caution in patients with liver disease. Dose adjustment of Nublexa Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised while you are taking this medicine. Use of Nublexa Tablet is not recommended in patients with the severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Nublexa Tablet
₹2117.64/Tablet
Regonat Tablet
Natco Pharma Ltd
₹353.57/Tablet
save 83%
Resihance 40mg Tablet
Bayer Pharmaceuticals Pvt Ltd
₹1506.95/Tablet
save 29%

Quick Tips

  • Nublexa Tablet is used in the treatment of cancers of colon and rectum.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class
Diarylethers Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS

Patient Concerns

arrow
Is ulcers curable G2 stage of cancer in rectum area
Dr. Pawan Rawal
Gastroenterology
Needs evaluation Please meet a Gastro surgeon
My dad is suffering from colon cancer How to get rid of it
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Surgery is main stay of treatment, which should be followed by chemotherapy.
arrow
Do you have any questions related to Nublexa Tablet ?

User Feedback


FAQs

Q. Is Nublexa Tablet chemotherapy?

Yes, Nublexa Tablet is used as a chemotherapy to treat cancer of stomach (gastrointestinal stromal tumors), colon or rectal, in cases who have been treated with other cancer treatments or are incurable with other treatments

Q. Is Nublexa Tablet FDA approved?

Yes, Nublexa Tablet has been approved by US FDA since 2012

Q. How is Nublexa Tablet administered?

Nublexa Tablet needs to be administered orally as advised by your doctor. It is to be taken at the same time of the day

Q. Does Nublexa Tablet shrink tumors?

Yes, Nublexa Tablet works either by shrinking the tumor or stops it from growing further.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1203-204.
  2. Regorafenib. Reading, Berkshire: Bayer Plc.; 2013 [revised Aug. 2018]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Drugs.com. Regorafenib Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Bayer AG, Müllerstr. 178, 13353 Berlin
Expires on or after: April, 2021

A licensed vendor partner from your nearest location will deliver Nublexa Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP59294  Get 8% OFF
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₹54294
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28 tablets in 1 strip
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