Regorafenib is used to treat cancers of the colon or rectum and cancers of stomach (gastrointestinal stromal tumors), that has spread to other parts of the body or in patients not responding to or who are incurable with other treatments.
How it works
Regorafenib belongs to a class of drugs called as kinase inhibitors. It works by blocking the abnormal protein which cause multiplication of cancer cells and cutting the blood supply to the tumors, thereby slowing or stopping the growth of cancer cells.
Common side effects
Vomiting, Nausea, Liver enzyme increased, Muscle pain, Joint pain, Blood clotting disorder, Blood cortisol decreased, Cough with mucus, Decrease in red blood cell count, Decreased white blood cell count, Skin rash, Fever, Hair loss, Headache, Increased blood urea, Loss of appetite, Reduced blood platelets, Tremor, Weakness, Weight loss
- 1 variant(s)
- Do not repeat dose after vomiting. Seek your doctor’s advice. In case of missed dose, take the dose as soon as you remember on the same day. Do not take a missed dose next day.
- Seek immediate medical attention if you experience severe chest pain which may spread from the chest to shoulders, arms, back, neck, teeth, jaw or stomach, sudden colds sweats, or fainting.
- Inform your doctor if you have any liver disorders, bleeding disorders, high blood pressure, underwent surgery in the past or have a planned surgery.
- Inform your doctor, if you experience vomiting, stomach pain, bowel complaints with dark stools, pain, redness or blisters on palms or soles, or non-healing wounds, severe headache, eye disturbance, fits, confusion, memory loss or any other altered mental symptoms.
- Do not drive or operate machinery, if you experience treatment-related symptoms which could affect your ability to concentrate and react.
- Men and women planning pregnancy should use effective birth control while they are taking regorafenib for 2 months after they stop taking it.
- Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
- Do not take if patient is allergic to regorafenib or any of its ingredients.
Frequently asked questions
Q. Is regorafenib chemotherapy?
Yes, regorafenib is used as a chemotherapy to treat cancer of stomach (gastrointestinal stromal tumors), colon or rectal, in cases who have been treated with other cancer treatments or are incurable with other treatments.
Q. Is regorafenib FDA approved?
Yes, regorafenib has been approved by US FDA since 2012.
Q. How is regorafenib administered?
Regorafenib needs to be administered orally as advised by your doctor. It is to be taken at the same time of the day.
Q. Does regorafenib shrink tumors?
Yes, regorafenib works either by shrinking the tumor or stops it from growing further.