Regorafenib
Written By Dr. Anuj Saini
Reviewed By Dr. Rajeev SharmaLast updated 28 Mar 2025 | 06:01 AM (UTC)
Regorafenib Uses
Regorafenib is used in the treatment of pancreatic cancer, small cell lung cancer, liver cancer, kidney cancer, thyroid cancer, blood cancer (chronic myeloid leukaemia), gastrointestinal stromal tumour, cancer of colon and rectum, non-small cell lung cancer, soft tissue sarcoma, chronic idiopathic myelofibrosis and breast cancer.
How Regorafenib works
Regorafenib is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Common side effects of Regorafenib
Low blood platelets, Vomiting, Pain, Nausea, Infection, Fever, Anemia (low number of red blood cells), Diarrhea, High blood pressure, Decreased appetite, Stomatitis (Inflammation of the mouth), Headache, Fatigue, Weight loss, Hemorrhage
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Expert advice for Regorafenib
- Regorafenib is used in the treatment of cancers of colon and rectum.
- Take it with food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
- Regorafenib is used for the treatment of thyroid cancer.
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Frequently asked questions for Regorafenib
Yes, Regorafenib is used as a chemotherapy to treat cancer of stomach (gastrointestinal stromal tumors), colon or rectal, in cases who have been treated with other cancer treatments or are incurable with other treatments.
Regorafenib needs to be administered orally as advised by your doctor. It is to be taken at the same time of the day, with food.
Yes, Regorafenib works either by shrinking the tumor or stops it from growing further.