Nitoside 50mg Injection
Prescription Required
Product introduction
Nitoside 50mg Injection is a medicine used in the immediate treatment of hypertensive emergency (severely increased blood pressure) and acute heart failure. It brings about an immediate reduction in blood pressure and the workload of the heart.
Nitoside 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment.
Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure.
Nitoside 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment.
Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure.
Uses of Nitoside Injection
Side effects of Nitoside Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nitoside
- Cyanide poisoning
- Decreased blood pressure
How to use Nitoside Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nitoside Injection works
Nitoside 50mg Injection is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Nitoside 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Nitoside 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Nitoside 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Nitoside 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Nitoside 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Nitoside 50mg Injection is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Nitoside 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Nitoside 50mg Injection may be needed. Please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Nitoside 50mg Injection
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Quick tips
- Nitoside 50mg Injection is given as a drip (intravenous infusion) by your doctor or nurse.
- If there is no considerable improvement in blood pressure within 10 minutes, stop the infusion immediately.
- It may cause sudden lowering of blood pressure. Hence, regular monitoring of blood pressure is required during treatment.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitoside 50mg Injection as it may cause low blood pressure.
- You have been prescribed Nitoside 50mg Injection for the prevention and treatment of heart-related chest pain (angina).
- Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
- Nitoside 50mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
- Do not consume alcohol while taking Nitoside 50mg Injection as it may cause increased dizziness.
- It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
- You may develop tolerance to Nitoside 50mg Injection with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
- Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nitoside 50mg Injection as it may cause low blood pressure.
Fact Box
Chemical Class
Organic transition metal salts
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Nitric Oxide (NO) Donors
Interaction with drugs
Taking Nitoside with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a serious drop in blood pressure.
Do not consume Nitroprusside with Sildenafil.
Concomitant use may cause a serious drop in blood pressure.
Do not consume Nitroprusside with Sildenafil.
Concomitant use may cause a serious drop in blood pressure.
Do not consume Nitroprusside with Avanafil.
Concomitant use may cause a serious drop in blood pressure.
Do not consume Nitroprusside with Sildenafil.
Concomitant use may cause a serious drop in blood pressure.
Do not consume Nitroprusside with Sildenafil.
Patient concerns
FAQs
What is Nitoside 50mg Injection used for?
Nitoside 50mg Injection belongs to a class of medicines known as vasodilators. It is used to decrease the blood pressure in emergency conditions where the blood pressure is extremely high (hypertensive crisis). It is also used to maintain low blood pressure during surgical procedures in a hospital setting.
Why is Nitoside 50mg Injection wrapped in aluminum foil?
Nitoside 50mg Injection is wrapped in aluminum foil to protect it from light. This is because Nitoside 50mg Injection is very sensitive to light. The solution will degrade every 4 hours if left unprotected. On the contrary, covering it with aluminum foil makes it stable for around 24 hours.
How does Nitoside 50mg Injection decrease blood pressure?
Nitoside 50mg Injection widens the blood vessels (arteries and veins) which provides a better and smooth path for the blood to flow. This reduces the pressure on the walls which results in effective and significant decrease in the blood pressure.
What are the side effects of Nitoside 50mg Injection?
Nitoside 50mg Injection may cause side effects like low blood pressure and cyanide poisoning. Additionally, you may also notice abdominal pain, sweating, dizziness, headache, muscle twitching and nausea. However, these are usually not bothersome but if any of these side effects worry you or persist for a longer duration of time, please consult your doctor. Your doctor will suggest ways to manage or prevent these side effects.
Why is Nitoside 50mg Injection protected from light?
Nitoside 50mg Injection is extremely sensitive to light. If left open, its chemical composition changes rapidly and the color may change from brown to blue or green. If left unprotected, 20% of the solution will deteriorate every 4 hours even in glass bottles. Therefore, it is necessary to prevent exposure of Nitoside 50mg Injection to any kind of light, especially fluorescent light.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
- Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 184-86.
- Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 179-80.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 989.
- Drugs.com. Nitroprusside. [Accessed 20 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroprusside. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Marketer details
Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Country of origin: India
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1.0 Injection in 1 vial
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