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Pruside 50mg Injection

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Pruside 50mg Injection is a medicine used in the immediate treatment of hypertensive emergency (severely increased blood pressure) and acute heart failure. It brings about an immediate reduction in blood pressure and the workload of the heart.

Pruside 50mg Injection is given as a drip into the vein under the supervision of a doctor. Your doctor is the right person to decide the dose and duration, hence do not try to self-administered the injection at home. Regular monitoring of blood pressure is required while on treatment. 

Decreased blood pressure (hypotension) may occur as a side effect of this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. It is also advisable to avoid medication like sildenafil or tadalafil while on treatment as it may cause a sudden lowering of blood pressure.

Benefits of Pruside Injection

In Hypertensive emergency

Pruside 50mg Injection reduces stress on the heart by relaxing and widening the blood vessels. This makes it easier for the heart to pump blood around your body, thereby lowering your blood pressure. This medicine is injected into a vein under the supervision of a doctor. It is used for immediate reduction of very high blood pressure (hypertensive emergency). Controlled blood pressure reduces the risk of having a heart attack, stroke, or kidney problems.

In Acute Heart failure

Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen, and other parts of your body. Pruside 50mg Injection makes it easier for your heart to pump blood around your body and is, therefore, an effective treatment for heart failure.

This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes (such as eating healthily and keeping active) to help this medicine be effective.

Side effects of Pruside Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pruside

  • Cyanide poisoning
  • Decreased blood pressure

How to use Pruside Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pruside Injection works

Pruside 50mg Injection is a vasodilator. It works by relaxing the muscles in your blood vessels to help them widen and results in the lowering of blood pressure.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pruside 50mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Pruside 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pruside 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pruside 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Pruside 50mg Injection is safe to use in patients with kidney disease. No dose adjustment of Pruside 50mg Injection is recommended.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Pruside 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Pruside 50mg Injection may be needed. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Pruside 50mg Injection is given as a drip (intravenous infusion) by your doctor or nurse.
  • If there is no considerable improvement in blood pressure within 10 minutes, stop the infusion immediately.
  • It may cause sudden lowering of blood pressure. Hence, regular monitoring of blood pressure is required during treatment.
  • It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
  • Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Pruside 50mg Injection as it may cause low blood pressure.

Fact Box

Chemical Class
Organic transition metal salts
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
NO Donors

Interaction with drugs

Taking Pruside with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Joy On, One Up, Confidence
Life-threatening
Brand(s): Suvida Force, Tadagra, Tadafun
Life-threatening
Brand(s): Udzire
Life-threatening
Brand(s): Edafil
Life-threatening

Patient concerns

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how oftain can i take i pill in a year for emergency case pls tell me
Dr. Suman Rao
Obstetrics and Gynaecology
Should not be taken. It has high failure rates. Use some regular method for contraception
What is BNP test? Pls explain. What is BNP ASSAY?My result is133.0 explain
Dr. Manju Singh
Homeopathy
BNP levels below 100 pg/mL indicate no heart failure. BNP levels of 100-300 pg/mL suggest heart failure is present. BNP levels above 300 pg/mL indicate mild heart failure. BNP levels above 600 pg/mL indicate moderate heart failure.The level of BNP in the blood increases when heart failure symptoms worsen, and decreases when the heart failure condition is stable
arrow

FAQs

Q. What is Pruside 50mg Injection used for?

Pruside 50mg Injection belongs to a class of medicines known as vasodilators. It is used to decrease the blood pressure in emergency conditions where the blood pressure is extremely high (hypertensive crisis). It is also used to maintain low blood pressure during surgical procedures in a hospital setting.

Q. Why is Pruside 50mg Injection wrapped in aluminum foil?

Pruside 50mg Injection is wrapped in aluminum foil to protect it from light. This is because Pruside 50mg Injection is very sensitive to light. The solution will degrade every 4 hours if left unprotected. On the contrary, covering it with aluminum foil makes it stable for around 24 hours.

Q. How does Pruside 50mg Injection decrease blood pressure?

Pruside 50mg Injection widens the blood vessels (arteries and veins) which provides a better and smooth path for the blood to flow. This reduces the pressure on the walls which results in effective and significant decrease in the blood pressure.

Q. What are the side effects of Pruside 50mg Injection?

Pruside 50mg Injection may cause side effects like low blood pressure and cyanide poisoning. Additionally, you may also notice abdominal pain, sweating, dizziness, headache, muscle twitching and nausea. However, these are usually not bothersome but if any of these side effects worry you or persist for a longer duration of time, please consult your doctor. Your doctor will suggest ways to manage or prevent these side effects.

Q. Why is Pruside 50mg Injection protected from light?

Pruside 50mg Injection is extremely sensitive to light. If left open, its chemical composition changes rapidly and the color may change from brown to blue or green. If left unprotected, 20% of the solution will deteriorate every 4 hours even in glass bottles. Therefore, it is necessary to prevent exposure of Pruside 50mg Injection to any kind of light, especially fluorescent light.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
  2. Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 184-86.
  3. Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 179-80.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 989.
  5. Drugs.com. Nitroprusside. [Accessed 20 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroprusside. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Troikaa Pharmaceuticals Ltd
Address: Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Country of origin: India

137
Inclusive of all taxes
MRP141.5  3% OFF
1.0 Injection in 1 vial
SOLD OUT
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