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    Information about Nitroprusside

    Nitroprusside uses

    Nitroprusside is used in the treatment of heart failure and hypertensive emergency.

    How nitroprusside works

    Nitroprusside is a nitrate. It works by relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload. It thus prevents/treats attacks of angina (chest pain) and improves symptoms of heart failure.

    Common side effects of nitroprusside

    Decreased blood pressure

    Available Medicine for Nitroprusside

    • ₹131
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      1 variant(s)
    • ₹130
      Neon Laboratories Ltd
      1 variant(s)
    • ₹141
      Troikaa Pharmaceuticals Ltd
      1 variant(s)

    Expert advice for Nitroprusside

    • Headache (‘nitrate headache’) may occur but should go away after a few days of continued treatment.
    • You may develop tolerance to Nitroprusside with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
    • Eat healthy (low-fat, high-fibre, low-sodium diet), quit smoking, limit alcohol intake, increase your physical activity, watch your weight, and reduce stress.
    • Notify your doctor about other medicines (eg. sildenafil, tadalafil or vardenafil) that you are taking as Nitroprusside may interact with them and cause a serious fall in blood pressure. This may lead to collapse, unconsciousness and could be fatal.

    Frequently asked questions for Nitroprusside


    Q. Is Nitroprusside a nitrate?

    Yes, Nitroprusside is a nitrate

    Q. Is Nitroprusside an inotrope/ vasodilator?

    Nitroprusside is a vasodilator

    Q. Is nitroprusside the same as nitroglycerin?

    Nitroprusside and nitroglycerine are two different drugs with the same mechanism of action

    Q. Why Nitroprusside is protected from light?

    Nitroprusside is photosensitive and therefore it must be protected from light

    Q. Does Nitroprusside increased SVR (systemic vascular resistance)?

    Nitroprusside is known to relax the peripheral smooth muscles and therefore reduce SVR

    Q. Does Nitroprusside reduce afterload?

    Yes, Nitroprusside reduces afterload.

    Content on this page was last updated on 12 January, 2018, by Dr. Varun Gupta (MD Pharmacology)