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Nirpride 1mg Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Feb 2026 | 05:49 PM (IST)
Nirpride 1mg Tablet belongs to a group of medicines called sulfonylureas and is used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes such as kidney damage and blindness.
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General Information

The content is shown in English
Nirpride 1mg Tablet image
Nirpride 1mg Tablet image

Product introduction

Nirpride 1mg Tablet may be used alone or along with other medicines. It should be taken just before or with the first meal of the day. Take it regularly at the same time each day to get the maximum benefit. Your doctor will decide what dose is best for you and this may change from time to time according to your blood sugar levels.

Keep taking Nirpride 1mg Tablet, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise to put you at risk of diabetes complications such as kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking Nirpride 1mg Tablet include low blood sugar levels (hypoglycemia). It is important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and hence should be avoided. Some people may experience an increase in weight with this medicine.

You should not take Nirpride 1mg Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions, as it may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Nirpride Tablet

Benefits of Nirpride Tablet

Type 2 diabetes mellitus
Nirpride 1mg Tablet helps manage Type 2 diabetes by increasing the release of insulin from the pancreas, which lowers blood sugar levels. It helps reduce the risk of diabetes-related complications such as nerve damage, kidney problems, and heart disease, supporting better long-term health.

Side effects of Nirpride Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nirpride
  • Hypoglycemia (low blood glucose level)

How to use Nirpride Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nirpride 1mg Tablet should be taken with or after food.

How Nirpride Tablet works

Nirpride 1mg Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Quick tips

  • Take Nirpride 1mg Tablet shortly before or with the first main meal of the day (usually breakfast).
  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • Monitor your blood sugar level regularly while you are taking Nirpride 1mg Tablet.
  • Nirpride 1mg Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Be careful while driving or operating machinery until you know how Nirpride 1mg Tablet affects you.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Nirpride 1mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Nirpride 1mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Nirpride 1mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Nirpride 1mg Tablet
Driving

Driving

CAUTION
Nirpride 1mg Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Nirpride 1mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Nirpride 1mg Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Liver

Liver

CAUTION
Nirpride 1mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
However, the use of Nirpride 1mg Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.

Interaction with drugs

Taking Nirpride with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Disopyramide (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them.
Moderate

Amiodarone (Oral Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Amiodarone may raise blood levels of Glimepiride.
Moderate

Amiodarone (Injection Route)

If concurrent use is essential, watch out for symptoms such as confusion, headache, nausea, dizziness or faintness and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Amiodarone may raise blood levels of Glimepiride.
Moderate

Amisulpride (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Glimepiride.
Moderate

Amisulpride (Injection Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Amisulpride may reduce the efficacy of Glimepiride.

Frequently asked questions

Nirpride 1mg Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Nirpride 1mg Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Nirpride 1mg Tablet is principally eliminated by the kidneys.
No, it is not known that Nirpride 1mg Tablet causes memory loss. However, the use of Nirpride 1mg Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.
Nirpride 1mg Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Nirpride 1mg Tablet.
Nirpride 1mg Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Nirpride 1mg Tablet only controls the sugar levels but does not cure it. Do not stop taking Nirpride 1mg Tablet without talking to your doctor. If you stop taking Nirpride 1mg Tablet suddenly your diabetes may get worse.
No. Taking Nirpride 1mg Tablet on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Nirpride 1mg Tablet.
Yes, Nirpride 1mg Tablet can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.
It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.
Yes, Nirpride 1mg Tablet tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.
Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.
No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.
Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.
Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

Fact Box

Chemical Class

Benzenesulfonamides

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretagogues)

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255-1257.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 629-30.
  4. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 13 Mar. 2019] (online) Available from:
  5. DailyMed. Glimepiride [Drug Label Information]. [Accessed 20 Sept. 2021] (online) Available from:
  6. National Health Services. How and when to take glimepiride. [Last reviewed: 14 Mar. 2022]. [Accessed 28 June 2023]. (online) Available from:
  7. Glimepiride. MIMS; 2025 [Accessed 12 Feb 2026]. (online). Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Nircure Lifesciences Pvt. Ltd
Address: Unit-Plot No-05, Industrial Area Phase 2, Panchkula, Haryana 134113

Vendor Details

Country of origin: India
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