Nig 5mg Injection

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 06 Apr 2026 | 03:49 PM (IST)

Nig 5mg Injection is used to treat and prevent heart-related chest pain (angina) and hypertension (high blood pressure) during surgery. This medicine works by relaxing and widening blood vessels so blood can flow more easily to the heart. It has a very short-lived effect.

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Nig 5mg Injection is given as an injection under the supervision of a doctor with careful blood pressure monitoring. This is given as a continuous infusion into a vein and should not be stopped abruptly. It should not be mixed with any other medication of any kind.

The most common side effect of Nig 5mg Injection is a headache which may be severe. This can sometimes be helped by drinking plenty of fluids and avoiding alcohol. You may also experience lightheadedness, which could increase your risk of having a fall. There are other, rarer side effects, some of them serious. Ask your doctor and read the leaflet which comes with the medicine to make sure you are keeping safe.

Do not use Nig 5mg Injection if you are taking medicines to treat high blood pressure in your lungs (pulmonary hypertension), or erectile dysfunction; or if you have anemia or glaucoma (increased pressure inside the eye). Always tell your doctor what other health conditions you have and what other medicines you are taking. It is best not to drink alcohol with this medicine as it increases some of the side effects. If you are affected by dizziness, avoid driving. If you are pregnant, thinking about becoming pregnant, or breastfeeding, ask your doctor before taking this medicine.

Uses of Nig Injection

Benefits of Nig Injection

Treatment of Hypertension (high blood pressure)
Nig 5mg Injection is used to treat hypertension in hypertensive emergencies. It rapidly dilates (widens) the blood vessels. This rapid vasodilation helps reduce blood pressure levels, relieving the strain on the heart and improving blood flow to vital organs. It is typically used in critical situations where immediate blood pressure reduction is necessary, such as severe high blood pressure that can lead to organ damage or other life-threatening complications.

Side effects of Nig Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nig

Blurred vision
Decreased blood pressure
Dizziness
Headache
Increased heart rate
Lightheadedness
Paresthesia (tingling or pricking sensation)

How to use Nig Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nig Injection works

Nig 5mg Injection is a nitrate. It works by improving blood supply to heart and relaxing the blood vessels which decreases the oxygen demand of the heart and reduces its workload, thereby preventing/treating attacks of angina (chest pain). Relaxation of blood vessels lowers blood pressure.

All substitutes for Nig 5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Myonit Injection

by Troikaa Pharmaceuticals Ltd.

₹31.26/injection

19% cheaper

Nitrosol 5mg Injection

by Shree Ganesh Pharmaceuticals

₹33.75/injection

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Quick tips

It is given via a drip into a vein under the supervision of a doctor.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
Nig 5mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nig 5mg Injection as it may cause increased dizziness.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nig 5mg Injection as it may cause low blood pressure.
You have been prescribed Nig 5mg Injection for the prevention and treatment of heart-related chest pain (angina).
Eat healthy (low-fat, high-fiber, low-sodium diet), quit smoking, increase your physical activity, watch your weight and reduce stress.
Nig 5mg Injection may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
Do not consume alcohol while taking Nig 5mg Injection as it may cause increased dizziness.
It may cause headaches which usually go away after a few days of continued treatment. Inform your doctor if it persists.
You may develop tolerance to Nig 5mg Injection with time, meaning that the same dose may be less effective next time. Follow the prescribed dosing schedule to avoid this.
Stop taking medications (prescribed for erectile dysfunction) like sildenafil or tadalafil while on treatment with Nig 5mg Injection as it may cause low blood pressure.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nig 5mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Nig 5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Nig 5mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Nig 5mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Nig 5mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Nig 5mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Nig with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Sildenafil (Oral Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Tadalafil (Oral Route)

Do not consume Tadalafil with Nitroglycerin. If Tadalafil is essential, ensure a gap of at least 48 hours between taking Tadalafil and Nitroglycerin.

Life-threatening

Sildenafil (Oral Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Sildenafil (Injection Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Life-threatening

Sildenafil (Injection Route)

Do not consume Sildenafil with Nitroglycerin. If Sildenafil is essential, ensure a gap of at least 24 hours after discontinuing Nitroglycerin. Please consult your doctor.

Frequently asked questions

Does the effect of Nig 5mg Injection wear off after sometime?

Yes, excessive use of Nig 5mg Injection may cause tolerance which means that Nig 5mg Injection may lose its effectiveness on you. Therefore, doctors usually prescribe the smallest dose required for effective relief of acute angina attacks. Also, it is usually prescribed in morning and afternoon doses to give nitrate-free interval. Take it strictly as per the dosing interval prescribed by your doctor to prevent tolerance and maintain the effectiveness of Nig 5mg Injection.

What does too much Nig 5mg Injection do?

Excess Nig 5mg Injection may result in low blood pressure, sweating, nausea, vomiting, headache, weak and fast pulse. It may also cause weakness, lightheadedness on standing and the patient might even faint. The patient will require emergency medical treatment in such a case.

Does Nig 5mg Injection stop heart attacks?

Nig 5mg Injection is prescribed to prevent attacks of heart-related chest pain (angina) in patients with coronary artery disease. In this disease, the blood vessels (coronary arteries) which supply blood to the heart become narrow because of which the heart has to work harder to get enough oxygen. Nig 5mg Injection prevents angina by relaxing the blood vessels so that the heart does not have to work very hard. Also, relaxation of coronary arteries increases the oxygen supply to the heart.

Fact Box

Chemical Class

Alkyl nitrates

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Nitric Oxide (NO) Donors

Related lab tests

High Sensitive CRP

Kidney Function Test

Lipid Profile

Platelet Count

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 747-55.
Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 191, 195-97.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 986-88.
Nitroglycerin [FDA Label]. Deerfield, IL: Baxter Healthcare Corporation; 2014. [Accessed 15 Nov. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nitroglycerin. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Nitroglycerin Injection [Product Information]. [Accessed 02 Aug. 2023] (online) Available from:
Nitroglycerin Injection [FDA Label]. Shirley, NY: American Regent Laboratories Inc.; 2022. [Accessed 02 Aug. 2023] (online) Available from:

User feedback

What are you using Nig Injection for?

Angina (heart-related chest pain)

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Excellent

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Nig 5mg Injection

Save more with additional offers

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Nig Injection

Benefits of Nig Injection

Side effects of Nig Injection

How to use Nig Injection

How Nig Injection works

All substitutes for Nig 5mg Injection

Myonit Injection

Nitrosol 5mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Sildenafil (Oral Route)

Tadalafil (Oral Route)

Sildenafil (Oral Route)

Sildenafil (Injection Route)

Sildenafil (Injection Route)

Frequently asked questions

Does the effect of Nig 5mg Injection wear off after sometime?

What does too much Nig 5mg Injection do?

Does Nig 5mg Injection stop heart attacks?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

High Sensitive CRP

Kidney Function Test

Lipid Profile

Platelet Count

References

User feedback

What are you using Nig Injection for?

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests