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Tadalafil

Information

Uses

Tadalafil is used in the treatment of erectile dysfunction and pulmonary hypertension.
It is also used in erectile dysfunction with benign prostatic hyperplasia (enlarged prostate).

How it works

Tadalafil increases blood flow to the penis by relaxing the muscles in penile blood vessels. It helps to get an erection only if the person is sexually stimulated.

Common side effects

Headache, Nausea, Nasopharyngitis, Flushing (sense of warmth in the face, ears, neck and trunk), Dyspepsia, Muscle pain, Back pain, Pain in extremity

Available Medicine

  • ₹142 to ₹269
    Macleods Pharmaceuticals Pvt Ltd
    2 variant(s)
  • ₹32 to ₹1339
    Dr Reddy's Laboratories Ltd
    5 variant(s)
  • ₹150
    Mankind Pharma Ltd
    1 variant(s)
  • ₹162
    Sun Pharmaceutical Industries Ltd
    1 variant(s)
  • ₹288
    Cipla Ltd
    1 variant(s)
  • ₹141
    Fourrts India Laboratories Pvt Ltd
    1 variant(s)
  • ₹39 to ₹390
    Fourrts India Laboratories Pvt Ltd
    3 variant(s)
  • ₹106 to ₹170
    Icon Life Sciences
    2 variant(s)
  • ₹83 to ₹187
    Zydus Cadila
    3 variant(s)
  • ₹96 to ₹165
    Ipca Laboratories Ltd
    2 variant(s)

Expert advice

  • Tadalafil helps to have and maintain an erection, but it will not produce the erection without sexual stimulation.
  • It should be taken one hour before sexual intercourse.
  • Inform your doctor if the erection does not subside within two hours after sexual intercourse.
  • Inform your doctor if you experience any eye sight change while taking Tadalafil.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Frequently asked questions

Tadalafil

Q. Is tadalafil addictive?
No, tadalafil is not an addictive drug. However, some people may develop an emotional or psychological dependence on the medicine. Always take the medicine for the duration as suggested by your doctor.
Q. Can I take tadalafil with prednisone?
Tadalafil, when taken with prednisone, may cause low blood pressure. Please consult your doctor for the change of dose regimen or an alternative drug of choice that may be required when the two medicines are to be used together.
Q. Is tadalafil safe?
Tadalafil is a relatively safe medication when used for conditions like erectile dysfunction and benign prostatic hyperplasia. Common side effects seen with tadalafil are a headache, flushing, nasal congestion, dyspepsia, back pain, muscle pain, and pain in extremity. It should only be used as advised by your doctor.
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Q. Is tadalafil better than sildenafil?
Studies have shown that both sildenafil and tadalafil have comparable action and safety profiles. Both medicines are well tolerated.
Q. How long can I take tadalafil for?
Tadalafil should only be taken for the recommended period as per the prescription by a doctor.
Q. Can I take tadalafil with alcohol?
Alcohol should be avoided or should be taken in moderation when you are taking tadalafil. Drinking alcohol may affect your ability to get an erection and may temporarily lower your blood pressure. Consumption of large amounts of alcohol while taking tadalafil may lower blood pressure and can cause dizziness.
Q. Can I take tadalafil with high blood pressure?
Patients with uncontrolled hypertension should avoid taking tadalafil. It should be taken cautiously by patients who are on medications for high blood pressure. Consult your doctor if you are a hypertensive and want to take tadalafil.
Q. Can I take tadalafil with antibiotics?
Tadalafil can be taken safely with antibiotics. However, it is can be easily metabolised by an enzyme known as CYP3A4 and therefore should be taken cautiously with drugs which can affect this enzyme. Consult your doctor before taking antibiotics together with tadalafil.
Q. Can I take tadalafil with sildenafil?
Both tadalafil and sildenafil belong to a group of drugs called phosphodiesterase inhibitors. They both act by dilating the blood vessels and if taken together can cause lower blood pressure and a prolonged painful erection. Therefore, these two drugs should not be taken together. Please consult your doctor.
Q. Does tadalafil affect sperm count?
No, tadalafil has no known effect on sperm count. It is a medication used for erectile dysfunction, not to increase sperm count.
Q. Does tadalafil delay ejaculation?
No, tadalafil is not known to affect ejaculation. Please consult your doctor if you experience delayed ejaculation while taking tadalafil.
Q. Does tadalafil expire?
Like any other drug, tadalafil does have an expiry date and should not be used beyond that. Please check the package insert
Q. Does tadalafil work?
Yes, tadalafil is an effective medicine for conditions for which is indicated like erectile dysfunction and benign prostatic hyperplasia.
Q. How long does tadalafil last?
Generally effects of tadalafil last up to 36 hours, however, the effect may vary depending on the individual taking the medicine.
Q. Can I take tadalafil with high blood pressure?
If you are taking any medicines to treat high blood pressure (antihypertensives), taking tadalafil with antihypertensives may cause low blood pressure. Please consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required.
Q. Is tadalafil a steroid?
No, tadalafil is not a steroid. It is a phosphodiesterase enzyme inhibitor.
Q. Is tadalafil same as sildenafil?
Both tadalafil and sildenafil belong to the same class of drugs called phosphodiesterase inhibitors but they are different. They have the same mechanism of action but a different way of behaving in the body.
Q. Can I take tadalafil forever?
No, tadalafil should only be taken as per the prescription and only for a period specified in the prescription by the doctor. Consult your doctor for the continuation of therapy.
Q. Can I take tadalafil just for fun?
Tadalafil is a prescription drug and should only be taken for the appropriate indication as prescribed by a doctor as it may be associated with its own side effects. Also, it is available only on prescription by a doctor.
Q. Can I take tadalafil with tamsulosin?
When taken together, these drugs may produce an additive blood-pressure-lowering effect. Dose needs to be titrated carefully. Please consult your doctor before taking these medications together.
Q. Can I take tadalafil with food?
Tadalafil can be taken with or without food. Its absorption is not known to be affected by food intake.
Q. Can I take tadalafil with lisinopril?
Tadalafil can be taken with lisinopril but when taken together they may cause increased lowering of blood pressure. They should, therefore, be taken together only after consulting with your doctor.
Q. Can I take tadalafil with metoprolol?
Tadalafil, when taken with metoprolol, may cause an additional blood-pressure-lowering effect. They can be taken together only with a physician's advice. Consult your doctor before taking them together.
Q. Does tadalafil cure erectile dysfunction?
Tadalafil acts by increasing blood flow to the penis. It is not a cure for erectile dysfunction, but it produces an erection by relaxing penile smooth muscles and increasing blood flow.
Q. Does tadalafil increase the size of the penis?
No, tadalafil is a phosphodiesterase inhibitor, It does not increase the size of the penis.
Q. Does tadalafil lower blood pressure?
Tadalafil itself does not have a significant effect on blood pressure. However, when used along with other medications which lower blood pressure, it can have a potentiating effect. Talk to your doctor in case you are taking blood pressure lowering medicines and you are also advised to take tadalafil.
Q. Does tadalafil increase testosterone?
Tadalafil is not known to have any effect on testosterone levels. Please consult your doctor if you are testosterone levels are lower and treatment is needed.

Content on this page was last updated on 18 May, 2017, by Dr. Varun Gupta (MD Pharmacology)