Neotid 400mg Tablet

Cimetidine (400mg)

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Neotid 400mg Tablet is a medicine used to treat benign stomach ulcers, duodenal ulcers, and gastroesophageal reflux disease (acid reflux). It helps reduce excess stomach acid, supporting ulcer healing and relieving symptoms such as heartburn, acidity, indigestion, and upper abdominal discomfort.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Apr 2026 | 03:49 PM (IST)

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General Information

Contains

Cimetidine (400mg)

Marketer

Neon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Consider taking Neotid 400mg Tablet before meals to prevent the symptoms of acidity. Take it in the dose and duration as advised by the doctor. If the symptoms persist or worsen even after 14 days of treatment, you should consult your doctor for further guidance. It is not recommended to take this medicine in severe stomach disease. You can help the medicine work better by eating smaller meals more often and avoiding spicy or oily foods.

Common side effects of Neotid 400mg Tablet include diarrhea, dizziness, tiredness, and rashes. These are usually mild and go away when you stop taking this medicine or as you adjust to it. Consult your doctor if any of these side effects bother you or do not go away.

Before taking Neotid 400mg Tablet, let your doctor know if you have any heart, kidney, or liver diseases so that your doctor can prescribe a suitable dose for you. Also, tell your doctor if you are taking other medications. Avoid drinking alcohol, as this can increase the amount of acid in your stomach and make your symptoms worse.

Uses of Neotid Tablet

Treatment of Benign Stomach ulcers
Treatment of Duodenal Ulcer
Treatment of Gastroesophageal reflux disease (Acid reflux)

Benefits of Neotid Tablet

Treatment of Benign Stomach ulcers
Neotid 400mg Tablet helps treat benign stomach ulcers by reducing the amount of acid produced in the stomach. Lowering acid levels allows the ulcer to heal more effectively and helps relieve symptoms such as stomach pain, burning, and discomfort after meals. Controlling acid secretion also reduces the risk of ulcer irritation and promotes faster recovery.

Treatment of Duodenal Ulcer
Neotid 400mg Tablet is beneficial in duodenal ulcers because it decreases excess stomach acid that can injure the lining of the duodenum. This reduction in acid supports faster healing of the ulcer and helps prevent further damage. It also relieves symptoms such as upper abdominal pain, acidity, and indigestion, improving overall digestive comfort.

Treatment of Gastroesophageal reflux disease (Acid reflux)
Neotid 400mg Tablet helps manage gastroesophageal reflux disease (GERD) by lowering the production of stomach acid that flows back into the esophagus (food pipe). This reduces irritation of the esophageal lining and helps relieve symptoms such as heartburn, sour taste, and regurgitation. Keeping acid levels under control also helps prevent complications related to long-term acid reflux.

Side effects of Neotid Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neotid

Skin rash
Tiredness
Diarrhea
Dizziness

How to use Neotid Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neotid 400mg Tablet may be taken with or without food.

How Neotid Tablet works

Neotid 400mg Tablet is a histamine H2 receptor antagonist. It works by reducing the amount of acid produced in the stomach, which helps relieve acid-related indigestion and heartburn.

Quick tips

Take Neotid 400mg Tablet before going to bed if you are taking this medicine once a day. It is very effective in controlling stomach acid that is released when you are asleep.
Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.
Inform your doctor if you do not feel better after taking Neotid 400mg Tablet for 2 weeks, as you may be suffering from some other problems.
Inform your doctor if you have ever been diagnosed with kidney disease, as the dose of your medicine may need to be adjusted.
Inform your doctor about any other medications or supplements that you are taking because Neotid 400mg Tablet can interfere with the working of other medications.
Do not stop taking the medication without talking to your doctor.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Neotid 400mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Neotid 400mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CAUTION

Neotid 400mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Neotid 400mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Neotid 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Neotid 400mg Tablet in patients with liver disease.

Interaction with drugs

Taking Neotid with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Phenytoin (Oral Route)

Do not consume Phenytoin with Cimetidine.

Severe

Carmustine (Injection Route)

If concurrent use is essential, your doctor may monitor blood cell counts and your overall treatment closely.

Severe

Fosphenytoin (Injection Route)

Do not consume Fosphenytoin with Cimetidine. If concurrent use is essential, please consult your doctor.

Severe

Phenytoin (Injection Route)

Do not consume Phenytoin with Cimetidine.

Severe

Dasatinib (Oral Route)

Cimetidine may reduce blood levels and efficacy of Dasatinib. Cimetidine may reduce blood levels and efficacy of Dasatinib.

Frequently asked questions

Why should Neotid 400mg Tablet be taken at bedtime?

Neotid 400mg Tablet may be prescribed as a single daily dose or in divided doses. When taken once daily, bedtime dosing is preferred because it helps suppress nighttime acid secretion more effectively. Taking it at the same time each night also makes it easier to remember your dose.

Can I take Neotid 400mg Tablet with antacids?

Yes, Neotid 400mg Tablet can be taken along with antacids, as they do not interfere with each other’s action. However, since both reduce acidity, using more than one acid-reducing medicine at the same time is generally unnecessary unless your doctor advises it.

Is there any vitamin or mineral loss when taking Neotid 400mg Tablet?

Neotid 400mg Tablet is not known to cause vitamin or mineral loss. However, medicines in the H2-blocker class may reduce the absorption of vitamin B12 when used for long periods (typically more than two years). If long-term therapy is needed, your doctor may monitor your vitamin B12 levels.

Are there any withdrawal symptoms after stopping Neotid 400mg Tablet?

No withdrawal symptoms have been reported after stopping Neotid 400mg Tablet. Available studies suggest that the medicine does not cause dependence or addiction.

Can I take Neotid 400mg Tablet with coffee?

There are no known harmful interactions between Neotid 400mg Tablet and coffee. However, Neotid 400mg Tablet may slow the breakdown of caffeine, which can increase its effects. Coffee itself can increase stomach acid and may worsen symptoms such as heartburn or acidity, so limiting coffee intake may help your condition.

Fact Box

Chemical Class

Imidazole derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Histamine Type-2 Receptor Antagonists (H2 Blockers)

Related lab tests

Helicobacter Pylori IgA

Helicobacter Pylori IgG

Helicobacter Pylori IgM

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Neotid 400mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Neotid Tablet

Benefits of Neotid Tablet

Side effects of Neotid Tablet

How to use Neotid Tablet

How Neotid Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Phenytoin (Oral Route)

Carmustine (Injection Route)

Fosphenytoin (Injection Route)

Phenytoin (Injection Route)

Dasatinib (Oral Route)

Frequently asked questions

Why should Neotid 400mg Tablet be taken at bedtime?

Can I take Neotid 400mg Tablet with antacids?

Is there any vitamin or mineral loss when taking Neotid 400mg Tablet?

Are there any withdrawal symptoms after stopping Neotid 400mg Tablet?

Can I take Neotid 400mg Tablet with coffee?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Helicobacter Pylori IgA

Helicobacter Pylori IgG

Helicobacter Pylori IgM

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests