Neotagmine 0.5mg Injection
Prescription Required
Product introduction
Neotagmine 0.5mg Injection is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.
Neotagmine 0.5mg Injection works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.
The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.
Neotagmine 0.5mg Injection works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.
The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.
Uses of Neotagmine Injection
- Treatment of Myasthenia gravis
- Treatment of Paralytic ileus
- Treatment of Post-operative urinary retention
- Reversal of effect of skeletal muscle relaxant after surgery
Benefits of Neotagmine Injection
In Treatment of Myasthenia gravis
Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Neotagmine 0.5mg Injection makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.
In Treatment of Paralytic ileus
Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Neotagmine 0.5mg Injection induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.
In Treatment of Post-operative urinary retention
After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Neotagmine 0.5mg Injection helps to improve this problem and treats postoperative urinary retention effectively.
In Reversal of effect of skeletal muscle relaxant after surgery
Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Neotagmine 0.5mg Injection is given to reverse this effect and cause muscle contraction again to restore normal function.
Side effects of Neotagmine Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Neotagmine
- Nausea
- Vomiting
- Slow heart rate
How to use Neotagmine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Neotagmine Injection works
Neotagmine 0.5mg Injection is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.
Safety advice
Alcohol
UNSAFE
Neotagmine 0.5mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Neotagmine 0.5mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Neotagmine 0.5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Neotagmine 0.5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Neotagmine 0.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Neotagmine 0.5mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Liver
SAFE IF PRESCRIBED
Neotagmine 0.5mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Neotagmine 0.5mg Injection may not be needed in these patients. Please consult your doctor.
What if you forget to take Neotagmine Injection?
If you miss a dose of Neotagmine 0.5mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Neotagmine 0.5mg Injection
₹5.4/Injection
Myostigmin 0.5mg Injection 1ml
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Neotroy 0.5mg Injection
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₹21.7/injection
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Stimin 0.5mg Injection
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₹4.9/injection
12% cheaper
Beemine 0.5mg Injection
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₹21.2/injection
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Nestig 0.5mg Injection
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₹17/injection
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Quick tips
- It is given into veins, muscles or under the skin by a healthcare professional.
- Do not drink alcohol while taking this medicine as it may worsen the side effects.
- Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.
Fact Box
Chemical Class
Phenoxy Compounds
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Cholinesterase inhibitors- carbamates
Interaction with drugs
Taking Neotagmine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause slow heartbeat.
watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you exper
Amikacin may reduce the efficacy of Neostigmine.
Your doctor may monitor the effects of Neostigmine along with your overall treatment and adjust the doses as per the observations.
Norfloxacin may increase the side effects of Neostigmine.
Caution is advised when taking Norfloxacin with Neostigmine if you have myasthenia gravis (a chronic autoimmune disorder
Neostigmine may increase the effect of Rivastigmine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Gentamicin may reduce the efficacy of Neostigmine.
Your doctor may monitor the effects of Neostigmine along with your overall treatment and adjust the doses as per the observation
Patient concerns
FAQs
Does Neotagmine 0.5mg Injection treat myasthenia gravis? How long do I need to take it?
Neotagmine 0.5mg Injection relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Neotagmine 0.5mg Injection will depend on your condition. Do not stop taking Neotagmine 0.5mg Injection until and unless advised by your doctor, even if you start feeling better.
How long does Neotagmine 0.5mg Injection take to start working?
Neotagmine 0.5mg Injection takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.
Is Neotagmine 0.5mg Injection a steroid?
No, Neotagmine 0.5mg Injection is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Neotagmine 0.5mg Injection work by preventing the breakdown of a chemical called acetylcholine.
Does it cause weight gain?
No, Neotagmine 0.5mg Injection does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.
Is Neotagmine 0.5mg Injection safe to use?
Yes, Neotagmine 0.5mg Injection is safe if used in the dose and duration prescribed by the doctor.
I felt better when I started taking Neotagmine 0.5mg Injection but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?
If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Neotagmine 0.5mg Injection. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.
Can I take Neotagmine 0.5mg Injection for constipation?
No, Neotagmine 0.5mg Injection should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.
What should I do if I accidentally take more than the dose required?
You should seek immediate medical help in case of overdose of Neotagmine 0.5mg Injection.Excess of Neotagmine 0.5mg Injection may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.
Does Neotagmine 0.5mg Injection have any abuse potential?
No, there is no evidence of Neotagmine 0.5mg Injection having any abuse potential.
Who should not take Neotagmine 0.5mg Injection?
Neotagmine 0.5mg Injection should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Neotagmine 0.5mg Injection is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
- Drugs.com. Neostigmine Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
- Neostigmine. Gloucester Business Park, Gloucester: Hameln Pharmaceuticals Ltd.; 2001 [revised 12 Jan. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
- Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013. [Accessed 24 Sept. 2020]. (online) Available from:
Marketer details
Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Country of origin: India
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