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Beemine 0.5mg Injection

Neostigmine (0.5mg)

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Beemine 0.5mg Injection is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:01 PM (IST)

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General Information

Contains

Neostigmine (0.5mg)

Marketer

Biomiicron Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Beemine 0.5mg Injection works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.

The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.

Uses of Beemine Injection

Treatment of Myasthenia gravis
Paralytic ileus
Treatment of Post-operative urinary retention
Reversal of effect of skeletal muscle relaxant after surgery

Benefits of Beemine Injection

Treatment of Myasthenia gravis
Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Beemine 0.5mg Injection makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

Treatment of Post-operative urinary retention
After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Beemine 0.5mg Injection helps to improve this problem and treats postoperative urinary retention effectively.

Reversal of effect of skeletal muscle relaxant after surgery
Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Beemine 0.5mg Injection is given to reverse this effect and cause muscle contraction again to restore normal function.

Side effects of Beemine Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Beemine

Nausea
Vomiting
Slow heart rate

How to use Beemine Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Beemine Injection works

Beemine 0.5mg Injection is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

All substitutes for Beemine 0.5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It is given into veins, muscles or under the skin by a healthcare professional.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.
You have been prescribed Beemine 0.5mg Injection for treatment of myasthenia gravis.
It may also be used to treat inactivity of the muscle in the intestines (paralytic ileus) and difficulty in passing urine (urinary retention) after an operation.
Take it with food to avoid an upset stomach.
Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Beemine 0.5mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Beemine 0.5mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Beemine 0.5mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

CONSULT YOUR DOCTOR

It is not known whether Beemine 0.5mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Beemine 0.5mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.

Liver

SAFE IF PRESCRIBED

Beemine 0.5mg Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Beemine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Norfloxacin (Oral Route)

Caution is advised when taking Norfloxacin with Neostigmine if you have myasthenia gravis (a chronic autoimmune disorder in which antibodies destroy the communication between nerves and muscle, resulting in weakness of the skeletal muscles). Norfloxacin may increase the side effects of Neostigmine.

Moderate

Rivastigmine (Transdermal Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Neostigmine may increase the effect of Rivastigmine.

Moderate

Thalidomide (Oral Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations.

Moderate

Amikacin (Injection Route)

Your doctor may monitor the effects of Neostigmine along with your overall treatment and adjust the doses as per the observations. Amikacin may reduce the efficacy of Neostigmine.

Moderate

Gentamicin (Injection Route)

Your doctor may monitor the effects of Neostigmine along with your overall treatment and adjust the doses as per the observations. Gentamicin may reduce the efficacy of Neostigmine.

Frequently asked questions

Does Beemine 0.5mg Injection treat myasthenia gravis? How long do I need to take it?

Beemine 0.5mg Injection relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Beemine 0.5mg Injection will depend on your condition. Do not stop taking Beemine 0.5mg Injection until and unless advised by your doctor, even if you start feeling better.

How long does Beemine 0.5mg Injection take to start working?

Beemine 0.5mg Injection takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Is Beemine 0.5mg Injection a steroid?

No, Beemine 0.5mg Injection is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Beemine 0.5mg Injection work by preventing the breakdown of a chemical called acetylcholine.

Does it cause weight gain?

No, Beemine 0.5mg Injection does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Beemine 0.5mg Injection safe to use?

Yes, Beemine 0.5mg Injection is safe if used in the dose and duration prescribed by the doctor.

I felt better when I started taking Beemine 0.5mg Injection but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Beemine 0.5mg Injection. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Can I take Beemine 0.5mg Injection for constipation?

No, Beemine 0.5mg Injection should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Beemine 0.5mg Injection.Excess of Beemine 0.5mg Injection may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Does Beemine 0.5mg Injection have any abuse potential?

No, there is no evidence of Beemine 0.5mg Injection having any abuse potential.

Who should not take Beemine 0.5mg Injection?

Beemine 0.5mg Injection should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Beemine 0.5mg Injection is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

Fact Box

Chemical Class

Phenoxy compounds

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Carbamate-Based Cholinesterase Inhibitors

Related lab tests

Acetyl Choline Receptor Antibody

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Neostigmine. Gloucester Business Park, Gloucester: Hameln Pharmaceuticals Ltd.; 2001 [revised 12 Jan. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013. [Accessed 24 Sept. 2020]. (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biomiicron Pharmaceuticals
Address: 18, Dr. Ambedkar Road, Kodambakkam, Chennai 600 024

Vendor Details

A licensed vendor partner from your nearest location will deliver Beemine 0.5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?

Beemine 0.5mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Beemine Injection

Benefits of Beemine Injection

Side effects of Beemine Injection

How to use Beemine Injection

How Beemine Injection works

All substitutes for Beemine 0.5mg Injection

Myostigmin 0.5mg Injection 1ml

Stimin 0.5mg Injection

Neotroy 0.5mg Injection

Myostigmin 0.5mg Injection 1ml

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Norfloxacin (Oral Route)

Rivastigmine (Transdermal Route)

Thalidomide (Oral Route)

Amikacin (Injection Route)

Gentamicin (Injection Route)

Frequently asked questions

Does Beemine 0.5mg Injection treat myasthenia gravis? How long do I need to take it?

How long does Beemine 0.5mg Injection take to start working?

Is Beemine 0.5mg Injection a steroid?

Does it cause weight gain?

Is Beemine 0.5mg Injection safe to use?

I felt better when I started taking Beemine 0.5mg Injection but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

Can I take Beemine 0.5mg Injection for constipation?

What should I do if I accidentally take more than the dose required?

Does Beemine 0.5mg Injection have any abuse potential?

Who should not take Beemine 0.5mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Acetyl Choline Receptor Antibody

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests