Natclovir 500mg Injection is an antiviral medicine used to treat viral infections caused by cytomegalovirus (CMV) in immunocompromised people who have undergone an organ or bone marrow transplantation. It also reduces the risk of blindness in a serious eye infection caused by CMV, known as CMV retinitis.

Natclovir 500mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. It is given by slow intravenous (IV) infusion over a 1-hour period to avoid damage to the kidneys. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

Some side effects include vomiting, nausea, and increased liver enzymes. You may also notice some injection site reactions like pain, swelling, or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Natclovir Injection

Cytomegalovirus Infection

Benefits of Natclovir Injection

In Cytomegalovirus Infection

Cytomegalovirus infection is a common virus infection that may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Natclovir 500mg Injection helps to prevent multiplication of the infection causing virus and treats the infection. It is given by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Natclovir Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Natclovir

Vomiting
Nausea
Injection site reaction
Increased liver enzymes

How to use Natclovir Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Natclovir Injection works

Natclovir 500mg Injection is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Natclovir 500mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Natclovir 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Natclovir 500mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Natclovir 500mg Injection may cause side effects which could affect your ability to drive.
You may feel sleepy, dizzy, confused or shaky, or you may lose your balance or have fits while using Natclovir 500mg Injection.

Kidney

CAUTION

Natclovir 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Natclovir 500mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.

Liver

CAUTION

Natclovir 500mg Injection should be used with caution in patients with liver disease. Dose adjustment of Natclovir 500mg Injection may be needed. Please consult your doctor.

What if you forget to take Natclovir Injection?

If you miss a dose of Natclovir 500mg Injection, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Fact Box

Chemical Class

Nucleoside analog

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral (Non-HIV) drugs

Interaction with drugs

Taking Natclovir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Abacavir

Brand(s): Abamune, A-Bec, Virol

Life-threatening

Adefovir

Brand(s): Adesera, Adheb, Adfovir

Life-threatening

Didanosine

Brand(s): Dinex EC, Dinosin, Virosine DR

Life-threatening

Entecavir

Brand(s): Entehep

Life-threatening

View all interactions

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

User feedback

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FAQs

Q. Is Natclovir 500mg Injection effective?

Natclovir 500mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Natclovir 500mg Injection too early, the symptoms may return or worsen.

Q. How is Natclovir 500mg Injection administered?

Natclovir 500mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Natclovir 500mg Injection.

Q. Is Natclovir 500mg Injection safe?

Natclovir 500mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Q. What should I tell my doctor before starting treatment with Natclovir 500mg Injection?

Before starting treatment with Natclovir 500mg Injection, tell your doctor if you have any other health problems, like kidney or liver-related issues. This is because certain medical conditions may affect your treatment and you may even need dose modifications. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Consult your doctor if you are planning a baby, if you are pregnant or breastfeeding, before starting treatment with Natclovir 500mg Injection to avoid any harmful effects on the baby.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 851-52.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 613-14.
Ganciclovir sodium. Garden City, Hertfordshire: Roche Products Limited; 1988 [revised 16 May 2018]. [Accessed 23 Jan. 2019] (online) Available from:
Medscape. Ganciclovir. [Accessed 01 Apr. 2019] (online) Available from:
Ganciclovir. Nutley, New Jersey: Roche Pharmaceuticals. [Accessed 01 Apr. 2019] (online) Available from:

Manufacturer/Marketer address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Country of origin: India
Expires on or after: December, 2023

A licensed vendor partner from your nearest location will deliver Natclovir 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India