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18 Feb 2020 | 05:25 PM (IST)
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Natclovir 250 Capsule

Prescription Required

Overview

Introduction

Natclovir 250 Capsule is an antiviral medicine used to treat viral infections caused by cytomegalovirus in immunocompromised people who have undergone an organ or bone marrow transplantation. It also reduces the risk of blindness in a serious eye infection caused by CMV, known as CMV retinitis.

Natclovir 250 Capsule should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food for better absorption. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

Some side effects of this medicine include headache, dizziness, vomiting, nausea, fatigue, and fever. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Natclovir Capsule

  • Cytomegalovirus Infection

Side effects of Natclovir Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Natclovir

  • Headache
  • Dizziness
  • Vomiting
  • Nausea
  • Fatigue
  • Fever
  • Stomach pain
  • Diarrhea
  • Skin rash

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Stomach pain
    Try to get plenty of rest and relax. Putting a heat pad or covered hot water bottle on your stomach may relieve the stomach pain. It may help if you eat and drink slowly and have smaller and more frequent meals. Reduce your intake of coffee, tea and alcohol as these can make the pain worse. If you are in a lot of pain, speak to your doctor about possible medication. Your doctor may be able to prescribe some over-the-counter medicines to help reduce the pain.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Skin rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.

How to use Natclovir Capsule

Take this medicine in the dose and duration as advised by your doctor. Do not chew, crush or break it. Natclovir 250 Capsule is to be taken with food.

How Natclovir Capsule works

Natclovir 250 Capsule is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Natclovir 250 Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Natclovir 250 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Natclovir 250 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Natclovir 250 Capsule may cause side effects which could affect your ability to drive.
You may feel sleepy, dizzy, confused or shaky, or you may lose your balance or have fits while using Natclovir 250 Capsule.
Kidney
CAUTION
Natclovir 250 Capsule should be used with caution in patients with kidney disease. Dose adjustment of Natclovir 250 Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Liver
CAUTION
Natclovir 250 Capsule should be used with caution in patients with liver disease. Dose adjustment of Natclovir 250 Capsule may be needed. Please consult your doctor.

What if you forget to take Natclovir Capsule?

If you miss a dose of Natclovir 250 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Natclovir 250 Capsule
₹121.5/Capsule
₹121.25/Capsule
same price
Vitravene 250mg Capsule
Taj Pharma India Ltd
₹147.5/Capsule
21% costlier

Interaction with Drugs

Taking Natclovir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
LIFE-THREATENING
Brand(s): Adesera, Adheb, Adfovir
LIFE-THREATENING
Brand(s): Dinex EC, Dinosin, Virosine DR
LIFE-THREATENING
Brand(s): Entehep
LIFE-THREATENING

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FAQs

Q. Is Natclovir a vesicant/ antibiotic?

No, Natclovir is not a vesicant/ an antibiotic

Q. Is Natclovir?

Yes, Natclovir is dialyzabl

Q. Is Natclovir a chemotherapy drug?

Yes, Natclovir is a chemotherapy used for the treatment of viral infections. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Is Natclovir nephrotoxic?

Yes, Natclovir is known to have nephrotoxicity (toxic to kidneys)

Q. Is ganciclovir a protease inhibitor?

No, ganciclovir is not a protease inhibitor; it belongs to synthetic nucleoside analogues class of antivirals

Q. Does Natclovir cover hsv (hepes simplex virus)?

Yes, Natclovir may be used to treat hsv (hepes simplex virus)

Q. How does Natclovir cause myelosuppression?

Natclovir is directly toxic to colony forming stem cells inside bone marrow which is responsible for RBCs, WBCs and platelets formation, thereby causing myelosuppression.

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 851-52.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 613-14.
  4. Ganciclovir sodium. Garden City, Hertfordshire: Roche Products Limited; 1988 [revised 16 May 2018]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Mayo Clinic. Ganciclovir. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
A licensed vendor partner from your nearest location will deliver Natclovir 250 Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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