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Miniblock 100mg Injection

Esmolol (100mg)
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Miniblock 100mg Injection belongs to a group of medicines called beta-blockers. It is used to treat emergency high blood pressure (hypertension), angina (heart-related chest pain), irregular heart rhythms (arrhythmia).

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)
₹41.2 MRP ₹458% off 
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General Information

The content is shown in English
Miniblock 100mg Injection image
Miniblock 100mg Injection image

Product introduction

Miniblock 100mg Injection is administered under the supervision of a doctor or nurse. You should not self-administer this medicine at home. The dose and frequency depend on what you are taking it for and the severity of your condition. It is generally given along with continuous monitoring of blood pressure and heart rate.

The main side effects of this medicine are fatigue, headache, slow heart rate, feeling dizzy, and nausea. These are usually mild and short-lived. It may also cause shortness of breath or low blood pressure in some people. To reduce the risk of side effects your doctor will probably start the medicine at a low dose and gradually increase it. Consult your doctor if the side effects bother you or do not go away.

Before taking it, let your doctor know if you have any liver problems. It may also not be suitable for people who have a slow heart rate, severe circulation problems, severe heart failure, or low blood pressure. Pregnant or breastfeeding mothers should also consult their doctor before taking it. You must talk to your doctor to find out whether this medicine is suitable for you to use. Avoid drinking alcohol as it may increase certain side effects.

Benefits of Miniblock Injection

Treatment of Angina (heart-related chest pain)
Miniblock 100mg Injection relaxes the blood vessels so that blood can flow more easily around your body and makes sure that your heart is getting a good supply of oxygen. This makes it less likely that you will suffer chest pain caused by angina. This medicine can help increase your ability to exercise and go about your daily life more easily. It is given as an injection under the supervision of your doctor.
Treatment of Arrhythmia
Miniblock 100mg Injection is used to stabilize heart rhythms (particularly atrial fibrillation). It helps in normalizing an abnormal heart rhythm, preventing it from occurring in the first place, or slowing down the heart rate during an episode.
Treatment of Hypertensive emergency
Miniblock 100mg Injection belongs to a group of medicine called long-acting beta-blocker. It works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart beat with less force. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. It is given as an injection under the supervision of your doctor.

Side effects of Miniblock Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Miniblock
  • Nausea
  • Headache
  • Fatigue
  • Constipation
  • Diarrhea
  • Dizziness
  • Cold extremities
  • Slow heart rate

How to use Miniblock Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Miniblock Injection works

Miniblock 100mg Injection is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.

Quick tips

  • It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.
  • It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
  • Do not stop taking Miniblock 100mg Injection suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Miniblock 100mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Miniblock 100mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Miniblock 100mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Miniblock 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Miniblock 100mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
However, talk to your doctor if you have any underlying kidney disease. Regular monitoring of blood pressure, kidney function test, and potassium levels may be advised.
Liver

Liver

SAFE IF PRESCRIBED
Miniblock 100mg Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Miniblock with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Aminophylline (Oral Route)

If used together, Esmolol may interrupt the efficacy of Aminophylline.
Life-threatening

Theophylline (Oral Route)

Do not consume Theophylline with Esmolol in case of asthma or COPD (chronic obstructive pulmonary disease). If concurrent use is essential, watch out for breathlessness and dizziness and consult your doctor if you experience them.
Life-threatening

Theophylline (Injection Route)

Do not consume Theophylline with Esmolol in case of asthma or COPD (chronic obstructive pulmonary disease). If concurrent use is essential, watch out for breathlessness and dizziness and consult your doctor if you experience them.
Life-threatening

Aminophylline (Injection Route)

Do not consume Aminophylline with Esmolol in case of asthma or COPD (chronic obstructive pulmonary disease). If concurrent use is essential, watch out for breathlessness and dizziness and consult your doctor if you experience them.
Severe

Lidocaine (Injection Route)

watch out for symptoms such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. Esmolol may raise blood levels of Lidocaine.

Frequently asked questions

Miniblock 100mg Injection can cause weight gain, although very rarely. Please consult your doctor if you experience weight gain with Miniblock 100mg Injection as it could be due to some underlying condition that needs attention.
You can eat and drink normally while taking Miniblock 100mg Injection. However, making lifestyle changes like stopping smoking, eating healthy food and exercising regularly can further give a boost to your health.
You can continue playing sports while taking Miniblock 100mg Injection. Exercising regularly can help you in controlling your blood pressure. However, do not over do it or push yourself too hard while exercising or playing sports.

Fact Box

Chemical Class

Phenol ethers

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Beta blocker- Cardioselective

References

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 327.
  2. Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 177.
  3. Opie LH. β-Blocking Agents. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 30.
  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 496-97.
  5. Esmolol hydrochloride. Deerfield, Illinois: Baxter Healthcare Corporation; 2007. [Accessed 18 Mar. 2019] (online) Available from:
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Esmolol. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). Esmolol. [Accessed 18 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: USV Private Limited
Address: Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.

Vendor Details

Country of origin: India
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