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Esmolol

INFORMATION

Uses

Esmolol is used in the treatment of angina (chest pain), arrhythmias (abnormal heart beat), heart attack and increased blood pressure .

How it works

Esmolol belongs to the class of drugs called Beta-blockers. It binds to the ?-adrenergic receptors in the heart, blocks them, opposes the action of certain endogenous chemicals and slows the heart rate as well as relaxes the blood vessels, thereby controlling the arrhythmia and lowering the blood pressure.

Common side effects

Vomiting, Nausea, Agitation, Confusion, Fatigue, Headache, Decreased blood pressure, Injection site pain, Sleeping for unusually long periods

AVAILABLE MEDICINE

Expert advice

  • Esmolol may cause dizziness and lightheadedness. To avoid this, get up slowly after sitting or lying down.
  • The Esmolol may affect your blood sugar and cover up the symptoms of low blood sugar if you have diabetes.
  • Esmolol may reduce blood flow to your hands and feet, causing them to feel cold. Smoking may worsen this effect. Dress warmly and avoid the use of tobacco.
  • Consult your doctor whether to continue Esmolol before any scheduled surgery.
  • It is not the first-choice treatment for high blood pressure according to the latest guidelines, except if you have a heart failure or heart disease.
  • Adults over the age of 65 may be at greater risk for the side-effects.

Frequently asked questions

Esmolol

Q.Is esmolol a vasodilator?
Esmolol belongs to the class of drugs called beta-blocker, and can dilate blood vessels

Q.Is esmolol a vesicant?
Yes. Esmolol is a vesicant and can cause skin discoloration and necrosis if it leaks during infusion

Q.Is esmolol a vasopressor?
Esmolol is a vasodilator

Q.How is esmolol supplied?
Esmolol is supplied in the form of solution for injection or infusion

Q.What is esmolol drip?
Esmolol drip is the esmolol solution for injection or infusion

Q.Why is esmolol short acting?
Esmolol is short acting as it undergoes quick breakdown (hydrolysis) and has an elimination half-life of about 9 mins.


Content on this page was last updated on 05 December, 2016, by Dr. Varun Gupta (MD Pharmacology)